Publications

  • 60. Nganga J. B.; Jung, Y. J.; Si, Y.; Kim, M.; Ko, H.; Hwang, G. T., Lee, H. J.; Lee, H.-I.; Lee, J. K., “Photoinduced radical polymerization by methyl fluoresceins under visible light and the application to signal amplification of hydrogen peroxide”, Dyes Pigments 2022, 200, 110163.

  • 59. Hong, S. W.; Oh, G. J.; Hwang, G. T., “2-Dimethylaminofluorene-Labeled 2'-Deoxyuridine as a Turn-On Fluorescent Probe for i-Motif DNA”, ChemistrySelect 2021, 6, 8361–8364.

  • 58. Song, M.; Hwang, G. T., “Expanding the effectiveness of screening”, Nat. Chem. News & Views 2021, 13, 515–517.

  • 57. Park, J.; Choi, J.; Duong, M. T. H. Ahn, H.‐C. Hong, S. W.; Hwang, G. T.; An, J.; Chung, H. S.; Ahn, D.-R. “Chimeric crRNAs Retaining Activity of Cas12a with Potential to Improve Specificity”, Bull. Kor. Chem. Soc. 2021, 42, 87–90.

  • 56. Hong, S. W.; Lee, S. Y.; Hwang, G. T., “Fluorene-Labeled 2'-Deoxyuridine as an Environmentally Sensitive Probe for Detection of an Abasic Site”, ChemistrySelect 2020, 5, 14480–14483.

  • 55. Song, M.; Hwang, G. T., “DNA-encoded library screening as core platform technology in drug discovery: Its synthetic method development and applications in DEL synthesis”, J. Med. Chem. 2020, 63, 6578–6599.

  • 54. Lee, S. Y.; Hong, S. W.; Yeo, H.; Hwang, G. T., “The linkers in fluorene-labeled 2’-deoxyuridines affect fluorescence discriminating phenomena upon duplex formation”, RSC Adv. 2020, 10, 18853–18859.

  • 53. Shrestha, J.#; Hwang, G. T.#; Lee, T.; Kim, S. W.; Oh, Y. S.; Kwon, Y.; Hong, S. W.; Kim, S.; Moon, H. S.; Baek, D. J.; Park, E.-Y., "Synthesis and biological evaluation of BODIPY-PF-543", Molecules, 2019, 24, 4408 (#: equal contribution).

  • 52. Hwang, G. T.; Hwang, J. Y,; Lee, J.-Y., “플루오레세인 유도체, 이의 제조방법 이를 이용한 pH 센서”, Korea Patent, 10-1922351-00-00, 2018. 11. 20.

  • 51. Yoo, D. K.; An, H. J.; Khan, N. A.; Hwang, G. T.; Jhung, S. H., “Record-high adsorption capacities of polyaniline-derived porous carbons for the removal of personal care products from water”, Chem. Eng. J. 2018, 352, 71–78.

  • 50. Park, E.-Y.; Lee, T.; Oh, Y. S.; Lee, J.-Y.; Shrestha, J.; Hong, S. W.; Jin, Y. J.; Jo, G.; Kim, S.; Hwang, G. T.; Han, D.-S.; Baek, D. J., “Synthesis of dansyl labeled sphingosine kinase 1 inhibitor”, Chem. Phys. Lipids 2018, 215, 29–33.

  • 49. Lee, H.-J.; Eun, B.; Sung, E.; Hwang, G. T.; Ko, Y. K.; Cho, C.-W., “Catalytic enantioselective synthesis of carboxy-substituted 2-isoxazolines by cascade oxa-Michael-cyclization”, Org. Biomol. Chem. 2018, 16, 657–664.

  • 48. Hwang, J. Y.; Lee, J.-Y.; Cho, C.-W.; Choi, W.; Lee, Y.; Shim, S.; Hwang, G. T., “5-Bromo-4',5'-bis(dimethylamino)fluorescein: Synthesis and Photophysical Studies”, Molecules, 2018, 23, 219.

  • 47. Hong, S. W.; Hwang, G. T., “Photophysical Study of 2-Fluorenyl-1,2,3-Triazole-labeled 2’-Deoxyuridine and Its Oligonucleotide”, Bull. Kor. Chem. Soc. 2018, 39, 78–83.

  • 46. Hwang, J. Y.; Shim, S.; Hwang, G. T., “4’,5’-Bis(dimethylamino)fluorescein Exhibits pH-Dependent Emission Behavior Distinct From That of Fluorescein”, Asian J. Org. Chem. 2018, 7, 150–154.

  • 45. Hwang, G. T., “Single-Labeled Oligonucleotides Showing Fluorescence Changes upon Hybridization with Target Nucleic Acids”, Molecules, 2018, 23, 124.

  • 44. Lee, J. W.; Son, Y.-S.; Hwang, J. Y.; Park, Y.; Hwang, G. T., “pH-Responsive quencher-free molecular beacon systems containing 2’-deoxyuridine units labeled with fluorene derivatives”, Org. Biomol. Chem. 2017, 15, 7165–7172.

  • 43. Lee, J. W.; Son, Y.-s.; Lee, J.-Y.; Kim, M. H.; Woo, S.-K. Lee, K. C.; Lee. Y. J.; Hwang, G. T., “pH-Sensitive Fluorescent Deoxyuridines Labeled with 2-Aminofluorene Derivatives”, Tetrahedron 2016, 72, 5595-5601.

  • 42. Kim, M. J.; Hwang, G. T., “Fluorescent Oligonucleotides Containing a 2-Ethynylfluorene- or 2-Ethynylfluorenone-labeled 2´-Deoxyguanosine Unit: Fluorescence Changes upon Duplex Formation”, Bull. Kor. Chem. Soc. 2016, 37, 1290-1297.

  • 41. Kim, M. J.; Seo, Y.; Hwang, G. T., “Synthesis and photophysical properties of 2′-deoxyguanosine derivatives labeled with fluorene and fluorenone units: toward excimer probes”, RSC Adv. 2014, 4, 12012-12017.

  • 40. Lee, J.; Cho, H. Y.; Hwang, G. T., “Highly Efficient Quencher-Free Molecular Beacon Systems Containing 2-Ethynyldibenzofuran- and 2-Ethynyldibenzothiophene-Labeled 2′-Deoxyuridine Units”, ChemBioChem 2013, 14, 1353-1362.

  • 39. Cho, H. Y.; Woo, S. K.; Hwang, G. T., “Synthesis and photophysical study of 2′-deoxyuridines labeled with fluorene derivatives”, Molecules 2012, 17, 12061-12071.

  • 38. Ryu, J. H.; Heo, J. Y.; Bang, E.-K.; Hwang, G. T.; Kim, B. H., “Quencher-free linear beacon systems containing 2-ethynylfluorenone-labeled 2′-deoxyuridine units”, Tetrahedron 2012, 68, 72-78.

  • 37. Seo, Y.; Hwang, G. T., “Quencher-free Linear Beacon Systems with Dual Fluorene-labeled Deoxyuridines”, Bull. Kor. Chem. Soc. 2011, 32, 4129-4132.

  • 36. Heo, J. Y.; Hwang, G. T., “2-Aminobenzene Derivatives as Unnatural Nucleobases and Their DNA Duplex Stabilities”, Bull. Kor. Chem. Soc. 2010, 31, 3794-3796.

  • 35. Malyshev, D. A.; Pfaff,D. A.; Ippoliti, S. I.; Hwang, G. T.; Dywer, T. J.; Romesberg, F. E., “Solution structure, mechanism of replication, and optimization of an unnatural base pair”, Chem. Eur. J. 2010, 16, 12650-12659.

  • 34. Kim, K.-A.; Hwang, G. T., “DNA polymerase recognition of unnatural base pair: 1-Methoxy-3-methylbenzene and 6-methyl-1(2H)-isoquinolinone”, Bull. Kor. Chem. Soc. 2010, 31, 2724-2726.

  • 33. Lee, Y.-A.; Hwang, G. T., “A linear beacon system featuring an internal deoxyguanine quencher allows highly selective detection of single base mismatches”, Bull. Kor. Chem. Soc. 2010, 31, 2011-2014. (cover paper).

  • 32. Hwang, G. T.; Hari, Y.; Romesberg, F. E., “The effects of unnatural base pairs and mispairs on DNA duplex stability and solvation”, Nucleic Acids Res. 2009, 37, 4757-4763.

  • 31. Zimmermann, J.; Gundogdu, K.; Cremeens, M. E.; Bandaria, J. N.; Hwang, G. T.; Thielges, M. C.; Cheatum, C. M.; Romesberg, F. E., “Efforts toward developing probes of protein dynamics: vibrational dephasing and relaxation of carbon-deuterium stretching modes in deuterated leucine”, J. Phys. Chem. B, 2009, 113, 7991-7994.

  • 30. Seo, Y. J.; Hwang, G. T.; Ordoukhanian, P.; Romesberg, F. E., “Optimization of an unnatural base pair towards natural-like replication”, J. Am. Chem. Soc. 2009, 131, 3246-3252.

  • 29. Hari, Y. #; Hwang, G. T. #; Leconte, A. M.; Joubert N.; Hocek M.; Romesberg, F. E., "Optimization of the pyridyl nucleobase scaffold for polymerase recognition and unnatural base pair replication", ChemBioChem 2008, 9, 2796-2799 (# equal contribution ).

  • 28. Hwang, G. T.; Romesberg, F. E., “Unnatural substrate repertoire of A, B, and X family DNA polymerases”, J. Am. Chem. Soc. 2008, 130, 14872-14882.

  • 27. Jeong, H. S.; Seo, Y. J.; Bang, E. K.; Hwang, G. T.; Jung, J. H.; Jang, S. K.; Kim, B. H., “Cholesterol-linked pyrene excimer molecular beacon with enhanced cell permeability ", Nucleic Acids Symp. Ser. 2008, 52, 351-352.

  • 26. Leconte, A. M.; Hwang, G. T.; Matsuda, S.; Capek, P.; Hari, Y.; Romesberg, F. E., "Discovery, characterization, and optimization of an unnatural base pair for expansion of the genetic alphabet", J. Am. Chem. Soc. 2008, 130, 2336-2343.

  • 25. Hwang, G. T.; Leconte, A. M.; Romesberg, F. E., "Polymerase recognition and stability of fluoro-substituted pyridone nucleobase analogues", ChemBioChem 2007, 8, 1606-1611.

  • 24. Ryu, J. H.; Seo, Y. J.; Hwang, G. T.; Lee, J. Y.; Kim, B. H., "Triad base pairs containing fluorene unit for quencher-free SNP typing", Tetrahedron 2007, 63, 3538-3547.

  • 23. Seo, Y. J.; Jeong, H. S.; Bang, E.-K.; Hwang, G. T.; Jung, J. H.; Jang, S. K.; Kim, B. H., "Cholesterol-linked fluorescent molecular beacons with enhanced cell permeability", Bioconjugate Chem. 2006, 17, 1151-1155.

  • 22. Leconte, A. M.; Matsuda, S.; Hwang, G. T.; Romesberg, F. E., "Efforts towards expansion of the genetic alphabet: pyridone and methyl pyridone nucleobases", Angew. Chem., Int. Ed. 2006, 45, 4326-4329.

  • 21. Hwang, G. T.; Romesberg, F. E., "Substituent effects on the pairing and polymerase recognition of simple unnatural base pairs", Nucleic Acids Res. 2006, 34, 2037−2045.

  • 20. Seo, Y. J.; Hwang, G. T.; Kim, B. H., "Quencher free molecular beacon systems with two pyrene units in the stem region", Tetrahedron Lett. 2006, 47, 4037-4039.

  • 19. Seo, Y. J.; Hwang, G. T.; Kim, B. H., "Pyrene-labeled deoxyuridine and deoxyadenosine: fluorescent discriminating phenomena in their duplex and hairpin oligonucleotides", Nucleic Acids Symp. Ser. 2005, 49, 135-136.

  • 18. Hwang, G. T.; Seo, Y. J.; Kim, B. H., "Pyrene-labeled deoxyuridine and deoxyadenosine: fluorescent discriminating phenomena in their oligonucleotides", Tetrahedron Lett. 2005, 46, 1475-1477.

  • 17. Hwang, G. T.; Kim, B. H., "π-Conjugated dendrimers based on bis(enediynyl)benzene units", Org. Lett. 2004, 6, 2669-2672.

  • 16. Hwang, G. T.; Seo, Y. J.; Kim, B. H., "A highly discriminating quencher-free molecular beacon for probing DNA", J. Am. Chem. Soc. 2004, 126, 6528−6529.

  • 15. Hwang, G. T.; Seo, Y. J.; Kim, S. J.; Kim, B. H., "Fluorescent oligonucleotide incorporating 5-(1-ethynylpyrenyl)-2’-deoxyuridine: sequence-specific fluorescence changes upon duplex formation", Tetrahedron Lett. 2004, 45, 3543-3546.

  • 14. Hwang. G. T.; Son, H. S.; Ku, J. K.; Kim, B. H., "Synthesis and photophysical studies of bis-enediynes as tunable fluorophores", J. Am. Chem. Soc. 2003, 125, 11241-11248.

  • 13. Kim, B. H.; Hwang, G. T.; Kim, S. J., "Receptive and responsive molecules: design, synthesis, and evaluation", in Advanced macromolecular and supramolecular materials and processes; Kurt E. Geckeler Ed.; Plenum Publishers: New York, pp77-90, 2003 (invited book chapter).

  • 12. Hwang, G. T.; Kim, B. H., "Synthesis and binding studies of multiple calix[4]arenes", Tetrahedron 2002, 58, 9019-9028.

  • 11. Baek, N. S.; Kim, H. K.; Lee, Y.; Kang, J.-G.; Kim, T. J.; Hwang, G. T.; Kim, B. H., "Temperature effect on photoluminescent properties of red light-emitting materials based on Ru(II)-chelated complexes", Thin Solid Films 2002, 417, 111-115.

  • 10. Baek, N. S.; Kim, H. K.; Hwang, G. T.; Kim, B. H., "Synthesis and luminescent properties of novel silicon-based electroluminescent copolymers with ruthenium(II)-chelated complexes", Mol. Cryst. & Liq. Cryst. 2001, 370, 387-390.

  • 9. Kim, B. H.; Jeong, E. J.; Hwang, G. T.; Venkatesan, N., "Multiple cycloadditive macrocyclization: an efficient method for crown ether-type cyclophanes, bis-calix[4]arenes, and silamacrocycles", Synthesis (Feature Article) 2001, 2191-2202.

  • 8. Hwang. G. T.; Son, H. S.; Ku, J. K.; Kim, B. H., "Novel fluorophores: efficient synthesis and photophysical study", Org. Lett. 2001, 3, 2469-2471.

  • 7. Baek, N. S.; Jung, S.-H.; Oh, D. J.; Kim, H. K.; Hwang, G. T.; Kim, B. H., "Direct synthesis and luminescent properties of new silicon-based copolymers", Synth. Met. 2001, 121, 1743-1744.

  • 6. Hwang, G. T.; Kim, B. H., "Cyclophane-type bis-calix[4]arenes: efficient synthesis via quadruple cycloadditive macrocyclization and conformational study", Tetrahedron Lett. 2000, 41, 10055-10060.

  • 5. Hwang, G. T.; Kim, B. H., "Bis-calix[4]arenes with imine linkages: synthesis and binding study of thiopheno bis-calix[4]arene with viologens", Tetrahedron Lett. 2000, 41, 5917-5921.

  • 4. Lee, C. W.; Hwang, G. T.; Kim, B. H., "Novel silicon-bridged macrocycles: efficient synthesis by quadruple cycloadditive macrocyclization and intramolecular nitrile oxide dimerization", Tetrahedron Lett. 2000, 41, 4177-4180.

  • 3. Hwang, G. T.; Kim, B. H., "Ultramacrocycle with four calix[4]arenes: synthesis and x-ray crystal structure of a quadruple calix[4]arene", Synth. Commun. 2000, 30, 4205-4212.

  • 2. Kim, S. I.; Shin, T. J.; Ree, M.; Hwang, G. T.; Kim, B. H.; Han, H.; Seo, J., "Synthesis and characterization of new polyimides containing calix[4]arenes in the polymer backbone", J. Polym. Sci. Part A: Polym. Chem. 1999, 37, 2013-2026.

  • 1. Kim, B. H.; Ahn, M. K.; Hwang, G. T., "Hydrogen bonding patterns in sulfonylureas: pattern dependence on the nature of amine substituent", Bull. Korean Chem. Soc. 1999, 20, 273-275.