The Huoh Lab
at SUNY Downstate
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The Huoh Lab explores the convergence of immune mechanisms, nuclear condensate function and human disease.
The Huoh Laboratory studies how self-polymerizing nuclear proteins regulate gene expression programs in immunity. Our work focuses on transcriptional regulators such as Autoimmune regulator (Aire) and members of the Speckled-protein (SP) family, which form nuclear condensates that control diverse immune processes, including T cell tolerance, antiviral immunity, and immune homeostasis. By integrating biochemistry, cell biology, molecular immunology, and genomics, we aim to uncover how these assemblies control transcriptional programs in immune cells, and how disruption of these assemblies contributes to autoimmune and inflammatory diseases. Learn more >>
Research Assistant – motivated, curious, with a bachelor’s degree in molecular biology, biochemistry, or cell biology. Prior wet lab experience preferred; organizational skills and attention to detail essential.
Research Assistant – motivated, curious, with a bachelor’s degree in molecular biology, biochemistry, or cell biology. Prior wet lab experience preferred; organizational skills and attention to detail essential.
PhD Students – Rotations will be available for MCB Program students beginning Winter 2025 / Spring 2026. Come chat with us about your research interests!
PhD Students – Rotations will be available for MCB Program students beginning Winter 2025 / Spring 2026. Come chat with us about your research interests!
Postdoctoral Fellow – ambitious and innovative, ready to drive an independent research project in transcriptional regulation of immune tolerance and homeostasis.
Postdoctoral Fellow – ambitious and innovative, ready to drive an independent research project in transcriptional regulation of immune tolerance and homeostasis.
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