Welcome to the HP Lab at the UST, Korea Institute of Science and Technology Information (KISTI). Our research group focuses on leveraging data science, bioinformatics, and advanced computational methods to address complex challenges in biology and medicine.
At the intersection of big data and life sciences, we strive to develop innovative approaches for integrating and analyzing large-scale biological datasets. Our work spans several key areas:
Data mining and integration of genomic, and clinical data
Development of computational tools for drug repurposing and discovery
Application of network analysis to understand disease mechanisms
Single-cell biology including immune disorders
Application of LLM and DeepLearnings (AI)
We are committed to fostering a collaborative and interdisciplinary environment that encourages creative problem-solving and scientific excellence. Our team works closely with biologists, clinicians, and computer scientists to translate computational insights into meaningful biological and medical advances.
Whether you're a student, researcher, or potential collaborator, we welcome your interest in our work. Please explore our website to learn more about our ongoing projects, publications, and opportunities to join our team.
Thank you for visiting, and we look forward to pushing the boundaries of data-driven biomedical research together.
Hyojung Paik, Ph.D.
Principal Researcher and Associate Professor
Korea Institute of Science and Technology Information, University of Science and Technology
Comprehensive analysis of normal adjacent to tumor transcriptomes
D Aran, R Camarda, J Odegaard, H Paik, B Oskotsky, G Krings, A Goga, ...
Nature communications 8 (1), 1077
Repurpose terbutaline sulfate for amyotrophic lateral sclerosis using electronic medical records
H Paik, AY Chung, HC Park, RW Park, K Suk, J Kim, H Kim, KY Lee, ...
Scientific reports 5 (1), 8580
Secretory MPP3 reinforce myeloid differentiation trajectory and amplify myeloid cell production
YA Kang*, H Paik*, SY Zhang, JJ Chen, OC Olson, CA Mitchell, A Collins, ...
Journal of Experimental Medicine 220 (8), e20230088 (*equal contribution)
H Paik*, C Oh*, S Hussain, S Seo, SW Park, TL Ko, A Lee
Database 2024, baae111 (*equal contribution)
H Paik, J Lee, CS Jeong, JS Park, JH Lee, N Rappoport, Y Kim, HY Sohn, ...
Translational Psychiatry 12 (1), 389
Tracing diagnosis trajectories over millions of patients reveal an unexpected risk in schizophrenia
H Paik, MJ Kan, N Rappoport, D Hadley, M Sirota, B Chen, U Manber, ...
Scientific data 6 (1), 201