Pioneering label-free computational chemical imaging (CCI) by integrating advanced instrumentation and data science for biomedical research.
I am a Research Assistant Professor working with Prof. Ji-Xin Cheng at Boston University. My multifaceted research background encompasses coherent Raman scattering, photothermal imaging, computational optical imaging, image processing, and artificial intelligence.
My research is dedicated to pioneering Computational Chemical Imaging (CCI) — an interdisciplinary direction that develops computation-driven label-free chemical imaging technologies to study previously inaccessible biological processes across scales. I have originated numerous computation-driven instruments and algorithms that deliver next-generation stimulated Raman scattering (SRS) microscopes with unprecedented imaging speed (Light Sci. Appl. 2018; Nat. Commun 2021), molecular specificity (Sci. Adv. 2023; Adv. Sci. 2023; Theranostics 2024), and spatial resolution (Nat. Methods, 2025). Beyond SRS, I've also worked on novel label-free chemical imaging modalities via stimulated Raman and overtone photothermal absorption (Sci. Adv. 2023; Nat. Commun 2024), redefining sensitivity and penetration. These technological breakthroughs have enabled collaborative biomedical applications across scales, including synthetic biology, molecular virology, histopathology, cell metabolism, neurodegeneration, and aging.