Unlike traditional medical textbooks, the origins of the now legendary Handbook of Neurosurgery by Mark Greenberg took root in the late 1980's in the notes the author kept while taking care of his patients, from his weekly grand rounds presentations, and in the literature he read. Now in its 10th edition, the book that is often referred to as the "bible for neurosurgeons" has grown organically over the years to include more topics of importance to those who provide healthcare to patients with neurologic ailments, and to reflect advances in the understanding and management of the underlying conditions and diseases.

Now in an updated ninth edition, Handbook of Neurosurgery by Mark Greenberg is synonymous with the most classic neurosurgical handbook published to-date. It has enjoyed legendary status as the go-to manual for legions of neurosurgeons for more than a quarter century. The comprehensive and conveniently compact book brings together a wide range of clinical practice guidelines from disparate sources into an amazing one-stop resource.


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Renowned for its depth and breadth, the updated text with nearly 1,800 pages encompasses the entire spectrum of neurosurgery including anatomy, physiology, differential diagnosis, and current principles of nonsurgical and surgical management. The text covers a huge scope of inherited, developmental, and acquired neurological disorders impacting pediatric to geriatric patients. The easy-to-navigate print and electronic formats provide an intuitive foundation for studying the field of neurosurgery.

What follows are chapters covering neuroanatomy and physiology, neuroradiology, operations and procedures, developmental anomalies, toxicology, coma, brain death, cerebrospinal fluid, hydrocephalus, infections, seizures, spine/spinal cord, functional neurosurgery, pain, tumour, radiation therapy, peripheral nerves, neuro-ophthalmology, neuro-otology, head trauma, spine injuries, stroke, subarachnoid haemorrhage (SAH)/aneurysms, vascular malformations, intracerebral haemorrhage, and occlusive cerebrovascular disease. The concluding chapters deal with outcomes assessment and differential diagnosis before ending with an 88-page index listing over 3,500 items, followed by quick reference tables and a Rosenbaum eye chart with pupil gauge.

Recommended Audience: The book is a must for neurosurgery residents and useful quick reference for neuro-ophthalmologists, neurologists, and other practising physicians with patients who are about to be under the care of, under care of, or post care from neurosurgeons.

Modifications occur in both format and content with each new edition. This article offers a chapter-by-chapter description of what is covered in the 10th edition of ATLS, which was published in January.

The new Glasgow Coma Scale (GCS) is introduced in the 10th edition. This version of the GCS stresses reporting the numerical components of the score and adds a new designation, NT (not testable), to be used when a component of the score cannot be assessed.

All ATLS faculty (coordinators, educators, instructors, and course directors) must be aware of these content updates to be eligible to teach and facilitate 10th edition courses. In addition to the content changes summarized in this article, a number of other changes in the conduct and organization of the course have been implemented. To learn about these changes, an in-person or online update must be completed. In-person updates are encouraged and may be offered by faculty who have been trained in the updates at the regional, state, or site level. In the summer of 2018, an online update course through the ACS learning management system will be available for those individuals who are unable to attend an in-person update. Continuing Medical Education (CME) credits will be offered for the online update and may be offered for the in-person update if the CME award schedule and documentation compliances are followed by the site hosting the update course. Once the faculty member has completed training, a link to a multiple-choice examination will be sent via e-mail for completion.

This handbook was prepared to provide guidelines to assist you during your residency. This book prepares you for future practices in neurosurgery with capabilities that will allow you to interface with computer technology, molecular biologic sciences as well as the ewer discoveries in the neurosciences.

Haly Abbas was one of the pioneering physicians and surgeons of the Eastern world in the 10th century who influenced the Western world by his monumental work, The Royal Book. The book was first partly translated into Latin by Constantinus Africanus in the 11th century without citing the author's name. Haly Abbas was recognized in Europe after full translation of The Royal Book by Stephen of Antioch in 1127. The Royal Book has been accepted as an early source of jerrah-names (surgical books) in the Eastern world. The chapters regarding cranial fractures in Haly Abbas' work include unique management strategies for his period with essential quotations from Paul of Aegina's work Epitome. Both authors preferred free bone flap craniotomy in cranial fractures. Although Paul of Aegina, a Byzantine physician and surgeon, was a connection between ancient traditions and Islamic interpretation, Haly Abbas seemed to play a bridging role between the Roman-Byzantine and the School of Salerno in Europe.

1. Principles of Neural Science by Eric R. Kandel, James H. Schwartz, and Thomas M. Jessell. Publisher: McGraw-Hill, 5th edition, 2012. | 2. Clinical Neuroanatomy by Richard S. Snell. Publisher: Lippincott Williams & Wilkins, 7th edition, 2010. | 3. The Brain That Changes Itself: Stories of Personal Triumph from the Frontiers of Brain Science by Norman Doidge. Publisher: Penguin Books, 1st edition, 2007. | 4. Neurology Secrets by Joseph S. Kass and Eli M. Mizrahi. Publisher: Elsevier, 6th edition, 2020. | 5. Neurological Differential Diagnosis: A Case-Based Approach by Roongroj Bhidayasiri, Michael F. Waters, and Andrew J. Lees. Publisher: Wiley-Blackwell, 2nd edition, 2019. | 6. Handbook of Clinical Neurology edited by Michael J. Aminoff and Franois Boller. Publisher: Elsevier, 3rd edition, 2013. | 7. Brain Injury Medicine: Principles and Practice by Nathan D. Zasler, Douglas I. Katz, and Ross D. Zafonte. Publisher: Demos Medical Publishing, 2nd edition, 2013. | 8. Neurology Board Review: An Illustrated Study Guide by Michael S. Okun and Sean I. Savitz. Publisher: Demos Medical Publishing, 2nd edition, 2017. | 9. The Cognitive Neurosciences edited by Michael Gazzaniga. Publisher: MIT Press, 5th edition, 2014. | 10. The Human Brain Book by Rita Carter. Publisher: DK, 1st edition, 2019. | 11. Neuroanatomy: An Illustrated Colour Text by Alan R. Crossman and David Neary. Publisher: Elsevier, 6th edition, 2014. | 12. Neuroanatomy through Clinical Cases by Hal Blumenfeld. Publisher: Sinauer Associates, 2nd edition, 2010. | 13. Neurology: Clinical Practice by Walter G. Bradley, Robert B. Daroff, Gerald M. Fenichel, and Joseph Jankovic. Publisher: Elsevier, 7th edition, 2015. | 14. Clinical Neurophysiology by Jasper R. Daube and Devon I. Rubin. Publisher: Oxford University Press, 4th edition, 2016. | 15. Atlas of Clinical Neurology by Roger N. Rosenberg and David P. Moore. Publisher: Saunders, 3rd edition, 2013. | 16. Neurology and Neurosurgery Illustrated by Kenneth W. Lindsay and Ian Bone. Publisher: Churchill Livingstone, 5th edition, 2010. | 17. Clinical Neuropsychology: A Practical Guide to Assessment and Management for Clinicians by Laura H. Goldstein and Jane E. McNeil. Publisher: Wiley-Blackwell, 2nd edition, 2018. | 18. Clinical Neurology and Neurosurgery: Self-Assessment Colour Review by Neil D. Kitchen and David W. Bates. Publisher: CRC Press, 3rd edition, 2016. | 19. Neurological Rehabilitation by Darcy Ann Umphred. Publisher: Mosby, 6th edition, 2021. | 20. Neuro-Ophthalmology: Diagnosis and Management by Grant T. Liu and Nicholas J. Volpe. Publisher: Elsevier, 3rd edition, 2019. | 21. The Neurobiology of Learning and Memory by Jerry Rudy. Publisher: Sinauer Associates, 3rd edition, 2013. | 22. The Neuroscience of Intelligence by Richard J. Haier. Publisher: Cambridge University Press, 1st edition, 2017. | 23. Brain Rules: 12 Principles for Surviving and Thriving at Work, Home, and School by John Medina. Publisher: Pear Press, 2nd edition, 2014. | 24. Handbook of Neurosurgery by Mark S. Greenberg. Publisher: Thieme, 8th edition, 2016. | 25. Pediatric Neurology: Principles & Practice by Kenneth F. Swaiman, Stephen Ashwal, Donna M. Ferriero, and Nina F. Schor. Publisher: Elsevier, 6th edition, 2017. | 26. The Human Nervous System by Juergen K. Mai, George Paxinos, and Thomas Voss. Publisher: Academic Press, 4th edition, 2012. | 27. Handbook of Neurochemistry and Molecular Neurobiology edited by Abel Lajtha. Publisher: Springer, 3rd edition, 2007. | 28. The Synaptic Organization of the Brain by Gordon M. Shepherd. Publisher: Oxford University Press, 5th edition, 2004. | 29. The Tell-Tale Brain: A Neuroscientist\\\'s Quest for What Makes Us Human by V.S. Ramachandran. Publisher: W.W. Norton & Company, 1st edition, 2011. | 30. Neuroimmunology by Roland Martin and Hans Lassmann. Publisher: Springer, 2nd edition, 2011. | 31. The Neurosciences: Paths of Discovery edited by David W. Tank and John T. Guthrie. Publisher: MIT Press, 1st edition, 2010. | 32. Clinical Neurology: From the Classroom to the Exam Room by Aaron Berkowitz. Publisher: Wolters Kluwer, 2 Clinical Neurology: From the Classroom to the Exam Room by Aaron Berkowitz. Publisher: Wolters Kluwer, 2nd edition, 2019. | 33. Neurology Examination and Board Review by Nizar Souayah and Rup Tandan. Publisher: McGraw-Hill Education, 2nd edition, 2020. | 34. Neuroanatomy in Clinical Context: An Atlas of Structures, Sections, Systems, and Syndromes by Duane E. Haines. Publisher: Lippincott Williams & Wilkins, 10th edition, 2018. | 35. Stroke: Pathophysiology, Diagnosis, and Management edited by James C. Grotta, Gregory W. Albers, Joseph P. Broderick, Michael A. Levine, and Scott E. Kasner. Publisher: Elsevier, 7th edition, 2021. | 36. Headache and Facial Pain: What Do I Do Now? by Lawrence C. Newman and Morris Levin. Publisher: Oxford University Press, 1st edition, 2013. | 37. Principles of Neural Science by Eric Kandel, James Schwartz, and Thomas Jessell. Publisher: McGraw-Hill Education, 5th edition, 2012. | 38. The Neurology of Eye Movements by R. John Leigh and David S. Zee. Publisher: Oxford University Press, 5th edition, 2015. | 39. Neurological Differential Diagnosis: A Case-Based Approach by Alan B. Ettinger and Deborah M. Weisbrot. Publisher: Demos Medical Publishing, 2nd edition, 2018. | 40. Clinical Neuroanatomy Made Ridiculously Simple by Stephen Goldberg. Publisher: MedMaster, 5th edition, 2014. | 41. Oxford Handbook of Neurology edited by Hadi Manji, Sean Connolly, and Neil Kitchen. Publisher: Oxford University Press, 2nd edition, 2014. | 42. Atlas of Human Brain Connections by Marco Catani and Michel Thiebaut de Schotten. Publisher: Oxford University Press, 2nd edition, 2020. | 43. Basic Clinical Neuroscience by Paul A. Young and Paul H. Young. Publisher: Lippincott Williams & Wilkins, 4th edition, 2015. | 44. Neurology and Clinical Neuroscience by Roger A. Brumback. Publisher: Springer, 1st edition, 2016. | 45. Clinical Neuroanatomy by Richard S. Snell. Publisher: Lippincott Williams & Wilkins, 7th edition, 2010. | 46. Neurology: An Illustrated Colour Text by Geraint Fuller and Mark Manford. Publisher: Churchill Livingstone, 3rd edition, 2017. | 47. Neurology Secrets by Joseph S. Kass and Eli M. Mizrahi. Publisher: Elsevier, 6th edition, 2016. | 48. Neuropsychology Handbook of Perception and Cognition edited by Alexander R. Bowers and John W. Schlag. Publisher: Elsevier, 2nd edition, 2010. | 49. Movement Disorders: A Video Atlas by Joel S. Perlmutter and Mark J. Ledoux. Publisher: Wolters Kluwer, 2nd edition, 2019. | 50. Atlas of EEG, Seizure Semiology, and Management by Karl E. Misulis and Gregory L. Holmes. Publisher: Demos Medical Publishing, 2nd edition, 2020. | 51. Handbook of Clinical Neurology edited by Michael J. Aminoff, Francois Boller, and Dick F. Swaab. Publisher: Elsevier, 3rd edition, 2013. | The Neurobiology of Addiction by George F. Koob and Michael A. Arends. Publisher: Academic Press, 2nd edition, 2019 | 53. Clinical Neurophysiology of Sleep Disorders edited by Christopher J. Earley and Richard P. Allen. Publisher: Oxford University Press, 2nd edition, 2019. | 54. Neurology Self-Assessment: A Companion to Bradley\\\'s Neurology in Clinical Practice edited by Justin T. Jordan and Gerald M. Fenichel. Publisher: Elsevier, 7th edition, 2016. | 55. Head Injury: A Multidisciplinary Approach edited by Peter Reilly, Ross Bullock, and Claudia Robertson. Publisher: Cambridge University Press, 2nd edition, 2012. | 56. Behavioral Neurology and Neuropsychology edited by Todd E. Feinberg and Martha J. Farah. Publisher: McGraw-Hill Education, 2nd edition, 2012. | 57. The Brain and Behavior: An Introduction to Behavioral Neuroanatomy by David L. Clark and Nashaat N. Boutros. Publisher: Cambridge University Press, 3rd edition, 2018. | 58. Oxford Textbook of Cognitive Neurology and Dementia edited by Masud Husain, Jonathan M. Schott, and Richard J. Perry. Publisher: Oxford University Press, 1st edition, 2016. | 59. Neuro-Ophthalmology Illustrated by Valerie Biousse and Nancy J. Newman. Publisher: Thieme Medical Publishers, 2nd edition, 2016. | 60. The Neurology of Consciousness: Cognitive Neuroscience and Neuropathology by Steven Laureys and Giulio Tononi. Publisher: Academic Press, 2nd edition, 2016. | 61. Comprehensive Clinical Neurophysiology edited by Rolandicci P. Martin, Dong M. Ma, and Hiroshi Shibasaki. Publisher: Elsevier, 1st edition, 2015. | 62. Current Therapy in Neurologic Disease edited by Robert J. Kim-Farley and M. Flint Beal. Publisher: Mosby, 8th edition, 2015. | 63. Clinical Neuroanatomy for Medical Students by Richard S. Snell. Publisher: Lippincott Williams & Wilkins, 7th edition, 2010. | 64. Neuropsychological Assessment by Muriel D. Lezak, Diane B. Howieson, and Erin D. Bigler. Publisher: Oxford University Press, 5th edition, 2012. | 65. Clinical Neurophysiology of Disorders of the Spinal Cord and Spine edited by Erik Stalberg and Mamede de Carvalho. Publisher: Elsevier, 1st edition, 2017. | 66. Handbook of Neurological Sports Medicine: Concussion and Other Nervous System Injuries in the Athlete edited by Anthony Alessi and David Geier. Publisher: Demos Medical Publishing, 1st edition, 2015. | 67. Neuro-Ophthalmology: Diagnosis and Management edited by Grant T. Liu, Nicholas J. Volpe, and Steven L. Galetta. Publisher: Saunders, 2nd edition, 2016. | 68. The Brain Atlas: A Visual Guide to the Human Central Nervous System by Thomas A. Woolsey, Joseph Hanaway, and Mokhtar H. Gado. Publisher: Wiley-Liss, 3rd edition, 2007. | 69. Neurology at the Bedside by Daniel B. Hoch and Joshua Klein. Publisher: Springer, 1st edition, 2017. | 70. Handbook of Dystonia edited by Mark Hallett, Mahlon R. DeLong, and Alberto Albanese. Publisher: Informa Healthcare, 2nd | 71. Neurology Secrets by Joseph S. Kass and Eli M. Mizrahi. Publisher: Elsevier, 6th edition, 2016. | 72. Principles of Neural Science by Eric Kandel, James Schwartz, Thomas Jessell, Steven Siegelbaum, and A. J. Hudspeth. Publisher: McGraw-Hill Education, 5th edition, 2012. | 73. The Human Brain Book by Rita Carter. Publisher: DK, 3rd edition, 2019. | 74. Handbook of Neurosurgery by Mark S. Greenberg. Publisher: Thieme Medical Publishers, 9th edition, 2019. | 75. Handbook of Clinical Neurology: Neurodegenerative Disorders Part I edited by Michael J. Aminoff, Franois Boller, and Dick F. Swaab. Publisher: Elsevier, 1st edition, 2017. | 76. Neuroscience: Exploring the Brain by Mark F. Bear, Barry W. Connors, and Michael A. Paradiso. Publisher: Wolters Kluwer, 4th edition, 2015. | 77. Pediatric Neurology: A Case-Based Review edited by Tena Rosser and Richard Frye. Publisher: Demos Medical Publishing, 1st edition, 2018. | 78. Atlas of Neurosurgical Techniques: Brain edited by Laligam N. Sekhar and Richard Glenn Fessler. Publisher: Thieme Medical Publishers, 2nd edition, 2016. | 79. Neuroanatomy and Neurophysiology for Speech and Hearing Sciences by J. Anthony Seikel, David G. Drumright, and Douglas W. King. Publisher: Plural Publishing, 2nd edition, 2016. | 80. Handbook of Neurologic Music Therapy edited by Michael H. Thaut and Volker Hoemberg. Publisher: Oxford University Press, 1st edition, 2014. | 81. The Neuropsychology of Anxiety: An Enquiry into the Functions of the Septo-Hippocampal System by Jeffrey A. Gray and Neil McNaughton. Publisher: Oxford University Press, 2nd edition, 2003. | 82. Brain Injury Medicine: Principles and Practice edited by Nathan D. Zasler, Douglas I. Katz, and Ross D. Zafonte. Publisher: Demos Medical Publishing, 2nd edition, 2013. | 83. Motor Control and Learning: A Behavioral Emphasis by Richard A. Schmidt and Timothy D. Lee. Publisher: Human Kinetics, 6th edition, 2018. | 84. Clinical Neurology by Roger P. Simon and David Greenberg. Publisher: McGraw-Hill Education, 10th edition, 2018. | 85. Neuroimaging: The Essentials by Pina Sanelli and Laurie A. Loevner. Publisher: Thieme Medical Publishers, 2nd edition, 2018. | 86. Stroke: Pathophysiology, Diagnosis, and Management edited by James C. Grotta, Gregory W. Albers, Joseph P. Broderick, and Scott E. Kasner. Publisher: Elsevier, 6th edition, 2015. | 87. Pediatric Neurology: Principles & Practice edited by Kenneth F. Swaiman, Stephen Ashwal, Donna M. Ferriero, and Nina F. Schor. Publisher: Elsevier, 5th edition, 2012. | 88. Essentials of Clinical Neuroanatomy and Neurophysiology by Roger A. Barker and Francesca Cicchetti. Publisher: Churchill Livingstone, 2nd edition, 2014. | 89. Neurology and Neurosurgery Illustrated by Kenneth W. Lindsay and Ian Bone. Publisher: Churchill Livingstone, 5 | 90. Atlas of Neurology by G. David Perkin and Marc C. Weksler. Publisher: Elsevier, 2nd edition, 2011. | 91. Neurology and Neurosurgery Illustrated by Kenneth W. Lindsay and Ian Bone. Publisher: Churchill Livingstone, 5th edition, 2011. | 92. Handbook of Neurosurgery by Mark S. Greenberg. Publisher: Thieme Medical Publishers, 8th edition, 2016. | 93. Clinical Neuroanatomy by Stephen Waxman. Publisher: McGraw-Hill Education, 28th edition, 2018. | 94. Handbook of Clinical Neurology: Neurodegenerative Disorders Part II edited by Michael J. Aminoff, Franois Boller, and Dick F. Swaab. Publisher: Elsevier, 1st edition, 2017. | 95. The Human Brain Coloring Book by Marian C. Diamond and Arnold B. Scheibel. Publisher: Collins Reference, 1st edition, 1999. | 96. Neuroanatomy: An Atlas of Structures, Sections, and Systems by Duane E. Haines. Publisher: Lippincott Williams & Wilkins, 8th edition, 2016. | 97. The Neuroscience of Human Relationships: Attachment and the Developing Social Brain by Louis Cozolino. Publisher: W. W. Norton & Company, 2nd edition, 2014. | 98. Handbook of Neurosurgery by Mark S. Greenberg. Publisher: Thieme Medical Publishers, 7th edition, 2010. | 99. Essential Neuroscience by Allan Siegel and Hreday N. Sapru. Publisher: Lippincott Williams & Wilkins, 2nd edition, 2015. | 100. Neuro-Ophthalmology Illustrated edited by Valerie Biousse and Nancy J. Newman. Publisher: Thieme Medical Publishers, 2nd edition, 2012.

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