Background:  Estimates of the prevalence of mental disorders are vital for policy and practice. The aim of the current study was to compare estimates of point (30-day) prevalence of major depressive episode (MDE) derived from a lifetime diagnostic interview with estimates derived from an interview exclusively focussing on the 30 days prior to interview.

Results:  The risk of being diagnosed with current MDE having been interviewed with a lifetime interview was higher, but not significantly higher, than the risk of being diagnosed with current MDE having been interviewed with a current interview (RR=1.29, 95% CI: 0.82-2.03). Derived and comprehensive point prevalent cases were similar with regard to a range of depression-related clinical characteristics.


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Regional haze pollution can normally be divided into four stages comprising pre-accumulation, explosion, duration and dissipation, under which the physiochemical characteristics of aerosols were clearly distinct. In this study, the chemical compositions and mixing state of aerosols and their source apportionments during a regional haze pollution process in the North China Plain (NCP) were comparably discussed for the different haze evolution stages. Six main particle groups were identified, including carbon-rich particles (53.17%), K-rich particles (27.41%), heavy-metal particles (10.9%), sodium particles (5.61%), dust particles (1.62%) and ammonium particles (1.29%). Subsequently, the chemical components and size distributions of aerosols were found to vary during the different haze stages. Contrary to the OCEC, K-CN, Cu and Pb particles, the EC-nitrate, EC-secondary and Fe particle groups had increasing proportions with the development of the haze events. The fraction of K particles was higher during the pre-accumulation stage and descended rapidly during the subsequent haze stages. In contrast to the OCEC particles, the EC-nitrate and EC-secondary particles from 0.6 to 1.2 m increased significantly with haze deterioration, implying the enhancement (decline) of aged (primary) carbonaceous particles during the haze episode. The source contributions of PM2.5 changed with the evolution of the haze events, with the largest percentage up to 52.23% from residual and industry emissions during the explosion stage. In contrast to industry and direct combustion emissions, the aging process and traffic emission contributed increasingly with the aggravation of the haze episodes, with higher fractions of 33.17% and 15.57%, respectively, throughout the duration stage.

N2 - Background: Admissions of infants in England have increased substantially but there is little evidence whether this is across the first year or predominately in neonates; and for all or for specific causes. We aimed to characterise this increase, especially those admissions that may be avoidable in the context of postnatal care provision.Methods: A cross sectional analysis of 1,387,677 infants up to age one admitted to English hospitals between April 2008 and April 2014 using Hospital Episode Statistics and live birth denominators for England from Office for National Statistics. Potentially avoidable conditions were defined through a staged process with a panel.Results: The rate of hospital admission in the first year of life for physiological jaundice, feeding difficulties and gastroenteritis, the three conditions identified as potentially preventable in the context of postnatal care provision, increased by 39% (39.55 to 55.33 per 1000 livebirths) relative to an overall increase of 6% (334.97 to 354.55 per 1000 livebirths). Over the first year the biggest increase in admissions occurred in the first 0-6 days (RR 1.26, 95% CI 1.24 to 1.29) and 85% of the increase (12.36 to 18.23 per 1000 livebirths) in this period was for the three potentially preventable conditions. Conclusions: Most of the increase in infant hospital admissions was in the early neonatal period, the great majority being accounted for by three potentially avoidable conditions especially jaundice and feeding difficulties. This is may indicate missed opportunities within the postnatal care pathway and given the enormous NHS cost and parental distress from hospital admission of infants, requires urgent attention.

AB - Background: Admissions of infants in England have increased substantially but there is little evidence whether this is across the first year or predominately in neonates; and for all or for specific causes. We aimed to characterise this increase, especially those admissions that may be avoidable in the context of postnatal care provision.Methods: A cross sectional analysis of 1,387,677 infants up to age one admitted to English hospitals between April 2008 and April 2014 using Hospital Episode Statistics and live birth denominators for England from Office for National Statistics. Potentially avoidable conditions were defined through a staged process with a panel.Results: The rate of hospital admission in the first year of life for physiological jaundice, feeding difficulties and gastroenteritis, the three conditions identified as potentially preventable in the context of postnatal care provision, increased by 39% (39.55 to 55.33 per 1000 livebirths) relative to an overall increase of 6% (334.97 to 354.55 per 1000 livebirths). Over the first year the biggest increase in admissions occurred in the first 0-6 days (RR 1.26, 95% CI 1.24 to 1.29) and 85% of the increase (12.36 to 18.23 per 1000 livebirths) in this period was for the three potentially preventable conditions. Conclusions: Most of the increase in infant hospital admissions was in the early neonatal period, the great majority being accounted for by three potentially avoidable conditions especially jaundice and feeding difficulties. This is may indicate missed opportunities within the postnatal care pathway and given the enormous NHS cost and parental distress from hospital admission of infants, requires urgent attention.

These episodes were published between October 2000 and April 2021 and are a collection of the experiences, reflections and insights of our graduates. There is much wisdom in here and lots of really good advice.

In this special episode we decided to reflect and look back. What have we learnt from 2020 that will help us better prepare for whatever 2021 has in store? Welcome to our season one mix, the bits that made us think. be457b7860

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