Fujioka, Y.#, Kawai, K.#, Endo, K., Ishibashi, M., Iwade, N., Tuerde, D., Kaibuchi, K., Yamashita, T., Yamanaka A., Katsuno, M., Watanabe, H., Sobue, G. and Ishigaki, S*. (2024) Stress-impaired reward pathway promotes distinct feeding behavior patterns. Front. Neurosci. 18:1349366. doi: 10.3389/fnins.2024.1349366
Stresses cause deviated feeding patterns, fixated feeding.
The aberrant feedings are induced by impairments in the mesolimbic dopamine system.
Specific deactivation of the DA neurons at VTA reproduced those feeding patterns.