When 13-year-old Rachel Gardner goes to a hospital after apparently witnessing a murder, she wakes up with virtually no memories to find herself on floor B7 of a strange, underground facility, in which each unique floor houses one murderous resident in an environment elaborately tailored to their psychopathies. Rachel survives the resident of floor B7, who was her doctor at the hospital, by escaping to floor B6, where Isaac Foster resides.