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Objective: To identify characteristics differentiating the node-first presentation of Kawasaki disease (NFKD) from bacterial cervical lymphadenitis (BCL) and typical Kawasaki disease (KD).

Aims/hypothesis: Type 1 diabetes is the most frequent endocrine disease in children, with 65,000 children diagnosed worldwide every year. Up to 80% of these children present with diabetic ketoacidosis (DKA), which is associated with both short-term risks and long-term consequences. This study aimed to characterise the worldwide variation in presentation of type 1 diabetes to inform future interventions to reduce this excess morbidity and mortality.

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Conclusions/interpretation: This is the first description of the variation in frequency of DKA at presentation of type 1 diabetes in children across countries. It demonstrates large variations that may, at least in part, be explained by different levels of disease awareness and healthcare provision and suggests ways to decrease the excess morbidity and mortality associated with DKA at diagnosis.

The reported frequency of DKA as the first presentation of childhood T1DM ranges from 15% to 67% in various studies.5 More meaningfully, more than half of children younger than 3 years of age present with DKA as their first presentation of T1DM.5 Presenting symptoms of DKA include polyuria and polydipsia, weight loss, fatigue, altered mental status, and respiratory distress (ie, Kussmaul breathing).6 While polyuria and polydipsia frequently occur, Kussmaul breathing occurs in only 28% of DKA presentations.7 In addition to physiologic stressors, other risk factors for developing DKA include female sex, no family predisposition, African American race, a younger age (< 5 years old), and other social factors including low socioeconomic status, limited access to medical services, and unstable family circumstances.5,8,9

You may have been given a topic to talk about in your presentation, or you may get to choose your own topic. Either way, be sure of the angle you want to take in talking about it. What is the aim of the presentation? Do you need to have a narrow focus on one area of the topic or a wider, more general focus? Understanding what is expected of you in the presentation in essential as getting it right will have an impact on the marks you receive. Knowing what you are working towards and will ensure that your presentation is clear and to the point.

Remember, simply putting information on a slide and reading it aloud is not enough for a successful presentation. You need to make sure you fully understand and have properly researched the topic you are presenting. Read a range of book chapters, journal articles, and other sources to make sure you fully understand the subject.

Your presentation may require that you create slides in PowerPoint of another program. Creating your slides should come after you have done all your research and written work. Look at the information you have gathered and develop your slides point by point. Include a small number of bullet points per slide, 4 or 5 is about right. The slides should serve as a guide for you, with each bullet point working as a prompt which you then expand upon. Make sure that you use a large enough font size so that your presentation will be clear from all parts of the room.

Always have a back up option just in case things go wrong. For example, if your presentation is saved on the university network, bring a copy on a USB memory stick, just in case you have problems accessing the network. Make sure you know in advance what equipment will be provided to you. Will you have to bring your own laptop or will you have access to a computer and projector?

When you're logged into your Mentimeter account, you can create a new presentation, which will fall under My Presentations, in just a few simple steps (Note: If you are a part of a Team, and would like to create a Presentation for the team, under Shared Presentations, follow the same steps below):

To interact with your audience using Mentimeter, you can fill your presentation with questions and content slides. You can also add a fun Quiz competition to your presentation and our Q&A feature to enable the audience to ask questions directly to the presenter. If you have any of our paid subscriptions, you will also be able to import an existing presentation to Mentimeter.

This will make the presentation full screen and take you to the Presentation view. You can now control the presentation and go through the slides using the arrow keys and keyboard shortcuts, or by using the presentation menu. To open the presentation menu, hover your mouse cursor over the bottom-left corner of the slide.

If you prefer to start building your presentation from a template, click "Templates" instead of "New presentation". Use them as they are, or edit them so that they suit the content you want to share with your audience.

Numerous tips are spread around that you can succeed with your first presentation. I would particularly recommend four of them: Gain clarity about your personal attitude towards presentations. Focus on a few major topics and find the storyline of your presentation. Be interested in your audience and network actively. I promise you: Implement these tips, and you are already covering half the distance for your successful first presentation.

Do you also visualize yourself as a doctoral candidate on stage? Can you see and feel how you talk vividly and enthusiastically about your research project and how you successfully flirt with your audience? You can combine those images with positive emotions, creating a valuable cornerstone for your successful presentations.

One possibility would be to rehearse in front of your fellow students, in your science network, in front of friends or in a small group and get constructive yet critical feedback. You may find out strengths you already have. Maybe there is also a Toastmasters Club in your city where you can find motivated and open-minded people who can also provide valuable feedback for your presentations. Through regular training you will gain additional experience and sovereignty in your presentations. Last but not least, this kind of training helped me to deliver a convincing presentation while defending my dissertation. As a result, I was able to reply questions from the plenum and the examiners with confidence.

In a further step, you may solve the question of where you will deliver presentations in the future. Since I started studying, I myself have regularly attended scientific and working group conferences, given presentations and poster presentations. With increasing experience, those presentations made me a well-known researcher in the scientific community at the time.

Do you know PechaKucha? In this format, each of the 20 PowerPoint slides is automatically visible for 20 seconds only. The success of this kind of presentation depends especially on whether the speakers are able to keep it short and communicate to the point. This requires a clear focus on the essentials.

You will gain further reputation if you pack your presentation into exciting stories: Relate the contents of your presentation to each other. Uncover content-related connections instead of stringing together numerous results. During my time as a doctoral student, this was an uncomfortable and yet important learning process: in one of my first science presentations, for example, I worked through a wealth of series of numbers piece by piece. Contrary to my expectations, my audience was not enthusiastic about this. Rather, they quite rightly asked several times in the discussion about the context of the results: At the time, I had not yet communicated the meaning and objectives of my project in a recognizable way.

Will you deliver your first presentation in your working group, in a workshop or at a conference? Then you can enhance your presentation by linking your topic with the topics of your previous or subsequent speakers. Include comments and interesting findings from other presentations. Exchange ideas with your colleagues in advance or invite them to a personal discussion after your presentation. Consider beforehand which questions you would like to discuss.

If, in addition, you are able to pitch your presentation or topic in one sentence in an understandable way, it will also be easier for you to talk to your colleagues. As for the presentation, a positive attitude is the basis for this, so that you remain in memory with a successful presentation and gradually expand your network.

Dr. Stephen Wagner is a trainer and coach for presentations. As a geographer and natural scientist he has worldwide experience with research projects and presentations. He conveys complex content in a practical, entertaining and understandable way. He works at the interface of science, business and international communication and blogs on his website.

When you first create a presentation, you can choose a theme for your slides. A theme is a preset group of colors, fonts, background, and layouts. Your presentation's layout is the way your text and images are arranged on a slide.

Trousseau was the first to report venous thrombosis, which occurred during his own pancreatic cancer treatment. His name was used to define any thromboembolic episode as the first sign of hidden malignancy [7]. Cancer-related consequences such as coagulation abnormalities and infections, as well as therapeutic and diagnostic procedures can all produce strokes [8].

Multiple cerebral infarctions may be the earliest signs of an occult malignancy. Our case demonstrates how recurrent stroke can be the first clinical manifestation of a metastatic tumor, especially in the absence of conventional vascular risk factors, as well as the importance and implications of diagnosing malignancy-related strokes, and the practical difficulties clinicians face in managing an increasingly common condition with no clear guidelines. ff782bc1db