Selection ExploreASL-related Studies

Image processing in multi-center trials

Mutsaerts HJMM, Petr J, Thomas DL, Vita E de, Cash DM, Osch MJP va. et al. Comparison of arterial spin labeling registration strategies in the multi-center GENetic frontotemporal dementia initiative (GENFI). J Magn Reson Imaging 2017. doi:10.1002/jmri.25751.

Mutsaerts HJMM, Steketee RME, Heijtel DFR, Kuijer JPA, Van Osch MJPMJP, Majoie CBLM et al. Inter-vendor reproducibility of pseudo-continuous arterial spin labeling at 3 Tesla. PLoS One 2014; 9. doi:10.1371/journal.pone.0104108.

Mutsaerts HJ, Steketee RM, Heijtel DF, Kuijer JP, van Osch MJ, Majoie CB et al. Reproducibility of pharmacological ASL using sequences from different vendors: implications for multicenter drug studies. MAGMA 2015; 28. doi:10.1007/s10334-014-0480-1.

Mutsaerts HJMM, van Osch MJP, Zelaya FO, Wang DJJ, Nordhøy W, Wang Y et al. Multi-vendor reliability of arterial spin labeling perfusion MRI using a near-identical sequence: Implications for multi-center studies. Neuroimage 2015; 113. doi:10.1016/j.neuroimage.2015.03.043.

Steketee RME, Mutsaerts HJMM, Bron EE, Van Osch MJP, Majoie CBLM, Van Der Lugt A et al. Quantitative functional Arterial Spin Labeling (fASL) MRI - Sensitivity and reproducibility of regional CBF changes using pseudo-continuous ASL product sequences. PLoS One 2015; 10. doi:10.1371/journal.pone.0132929

Mutsaerts HJMM, Steketee RME, Heijtel DFR, Kuijer JPA, Van Osch MJP, Majoie CBLM et al. Inter-vendor reproducibility of pseudo-continuous arterial spin labeling at 3 Tesla. PLoS One 2014; 9: e104108.

Heijtel DFR, Mutsaerts HJMM, Bakker E, Schober P, Stevens MF, Petersen ET et al. Accuracy and precision of pseudo-continuous arterial spin labeling perfusion during baseline and hypercapnia: a head-to-head comparison with 15O H₂O positron emission tomography. Neuroimage 2014; 92: 182–192.

Mutsaerts HJMM, Van Osch MJP, Zelaya FO, Wang DJJ, Nordhøy W, Wang Y et al. Multi-vendor reliability of arterial spin labeling perfusion MRI using a near-identical sequence: Implications for multi-center studies. Neuroimage 2015; 113: 143–152.

Development free-lunch approach to acquire extra vascular information from ASL scans: (this is implemented in ExploreASL, see above)

Mutsaerts HJMM, Petr J, Vaclavu L, van Dalen JW, Robertson AD, Caan MWA et al. The spatial coefficient of variation in arterial spin labeling cerebral blood flow images. JCerebBlood Flow Metab 2017; 37: 271678X16683690-.

Mutsaerts HJMM, Van Dalen J, Heijtel DFR, Groot PFC, Majoie CBLM, Petersen ET et al. Cerebral perfusion measurements in elderly with hypertension using arterial spin labeling. PLoS One 2015; 10. doi:10.1371/journal.pone.0133717.

van Dalen JW, Mutsaerts HJMM, Nederveen AJ, Vrenken H, Steenwijk MD, Caan MWA et al. White matter hyperintensity volume and cerebral perfusion in older individuals with hypertension using arterial spin-labeling. Am J Neuroradiol 2016; In press. doi:10.3174/ajnr.A4828.

Work in longitudinal multi-center studies

Cole J, MWA C, Underwood J, De Francesco D, Van Zoest R, Mutsaerts H et al. No evidence for accelerated ageing-related brain pathology in treated HIV: longitudinal neuroimaging results from the Comorbidity in Relation to AIDS (COBRA) project. Clin Infect Dis 2018; In press.

Mutsaerts H, Mirza S, Rohrer J, Shirzadi S, Robertson A, Thomas D et al. Presymptomatic cerebral perfusion biomarker changes in genetic frontotemporal dementia. In: International Society for Magnetic Resonance in Medicine. 2016, p 2016.

Pharmaceutically related work

Mutsaerts HJ, Steketee RM, Heijtel DF, Kuijer JP, van Osch MJ, Majoie CB et al. Reproducibility of pharmacological ASL using sequences from different vendors: implications for multicenter drug studies. MAGMA 2015; 28. doi:10.1007/s10334-014-0480-1.

Schrantee A, Tamminga HGH, Bouziane C, Bottelier MA, Bron EE, Mutsaerts HJMM et al. Age-dependent effects of methylphenidate on the human dopaminergic system in young vs adult patients with attention-deficit/hyperactivity disorder: A randomized clinical trial. JAMA Psychiatry 2016; 73: 955–962.

Strang AC, Van Wijk DF, Mutsaerts HJMM, Stroes ESG, Nederveen AJ, Rotmans JI et al. Guideline treatment results in regression of atherosclerosis in type 2 diabetes mellitus. Diabetes Vasc Dis Res 2015; 12: 126–132.

Schrantee A, Mutsaerts HJMM, Bouziane C, Tamminga HGH, Bottelier MA, Reneman L. The age-dependent effects of a single-dose methylphenidate challenge on cerebral perfusion in patients with attention-deficit/hyperactivity disorder. NeuroImage Clin 2017;

On perfusion physiology

Clement P, Mutsaerts H, Vaclavu L, Ghariq E, Pizzini FB, Smits M et al. Variability of physiological brain perfusion in healthy subjects - A systematic review of modifiers. Considerations for multi-center ASL studies. J Cereb Blood Flow Metab 2017; In press. doi:10.1177/0271678X17702156.