Epigenetic mechanisms underlying inheritance of metabolic imprinting
Effects of macronutrients on Circadian clock regulation
Omics analysis on diabetes and cancer to identify biomarkers
NutriEpigenomics Lab conducts research on the mechanisms of metabolic changes through the regulation of genes related to nutrients or metabolites using multi-omics analyses such as genomics, transcriptomics, epigenomics, and metabolomics. By utilizing cellular differentiation models and genetically modified mouse models, the lab aims to elucidate the molecular regulatory mechanisms of nutrients or metabolites and identify molecular patterns associated with chronic diseases such as diabetes and cancer. Furthermore, our lab explores reversible regulatory strategies using nutritional substances.
Current projects are the followings: 1) Epigenetic mechanisms underlying inheritance of metabolic imprinting, 2) Effects of macronutrients on Circadian clock regulation, and 3) Omics analysis on diabetes and cancer to identify biomarkers.