We developed a function to allow users to perform robust joint testing of SNP and SNP-environment interaction within the PLINK software toolset for whole genome association analysis. The function was written using the R programming language. The software implements statistical methodology published in Almli et al. (2014).

Participants:

• Dr. Michael Epstein

Publications:

• Correcting Systematic Inflation in Genetic Association Tests That Consider Interaction Effects. JAMA Psychiatry, Dec. 1, 2014, 71(12), p. 1392-1399

Software:

• https://github.com/epstein-software/robust-joint-interaction