This R package is a modified version of the 'BiasedUrn' package developed by Agner Fog; the original package can be found on the CRAN site. We created this modified package to facilitate permutation-based testing of disease-exposure association in case-control studies that accounts for potential confounders. In particular, such permutation-based procedures can be used to adjust for confounders in case-control studies of rare genetic variation.

Participants:

• Dr. Michael Epstein

Publications:

• A Permutation Procedure to Correct for Confounders in Case-Control Studies, Including Tests of Rare Variation. AJHG, Aug. 10, 2012, 91(2), p. 215-223

Software:

• https://github.com/epstein-software/BiasedUrn