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Launched in 2008, the Recovery After an Initial Schizophrenia Episode (RAISE) was a large-scale research initiative testing coordinated specialty care treatments. RAISE aimed to determine the best ways to help people recover from a psychotic episode and to reduce the likelihood of future episodes and long-term disability.

Early diagnosis and appropriate treatment make it possible to recover from psychosis. Some people who receive early treatment never have another psychotic episode. For other people, recovery means the ability to live a fulfilling and productive life, even if psychotic symptoms sometimes return.

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Sometimes people have both manic and depressive symptoms in the same episode, and this is called an episode with mixed features. During an episode with mixed features, people may feel very sad, empty, or hopeless while at the same time feeling extremely energized.

A person may have bipolar disorder even if their symptoms are less extreme. For example, some people with bipolar II disorder experience hypomania, a less severe form of mania. During a hypomanic episode, a person may feel very good, be able to get things done, and keep up with day-to-day life. The person may not feel that anything is wrong, but family and friends may recognize changes in mood or activity levels as possible symptoms of bipolar disorder. Without proper treatment, people with hypomania can develop severe mania or depression.

Bipolar disorder is a lifelong illness. Episodes of mania and depression typically come back over time. Between episodes, many people with bipolar disorder are free of mood changes, but some people may have lingering symptoms. Long-term, continuous treatment can help people manage these symptoms.

The most common types of medications that health care providers prescribe include mood stabilizers and atypical antipsychotics. Mood stabilizers such as lithium or valproate can help prevent mood episodes or reduce their severity. Lithium also can decrease the risk of suicide. Health care providers may include medications that target sleep or anxiety as part of the treatment plan.

An episode is also a narrative unit within a continuous larger dramatic work. It is frequently used to describe units of television or radio series that are broadcast separately in order to form one longer series.[2] An episode is to a sequence as a chapter is to a book. Modern series episodes typically last 20 to 50 minutes in length.[3]

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Objective: The authors investigated associations between polygenic liabilities for bipolar disorder, major depression, and schizophrenia and episode polarity among individuals with bipolar disorder.

Methods: The sample consisted of 2,705 individuals diagnosed with bipolar disorder at Danish psychiatric hospitals between January 1995 and March 2017. DNA was obtained from dried blood spots collected at birth as part of routine screening. Polygenic risk scores (PRSs) for bipolar disorder, major depression, and schizophrenia were generated using a meta-PRS method combining internally and externally trained components. Associations between PRS and polarity at first episode, polarity at any episode, and number of episodes with a given polarity were evaluated for each disorder-specific PRS using logistic and negative binominal regressions adjusted for the other two PRSs, age, sex, genotype platform, and five ancestral principal components.

Conclusions: PRSs for bipolar disorder, major depression, and schizophrenia are associated with episode polarity and psychotic symptoms in a congruent manner among individuals with bipolar disorder.

In this episode, we're offering helpful insights for home-schooled students who are navigating the college process. What are the curriculum requirements to qualify for college? What do schools look for in home-schooled applicants? How you can prove that you're prepared for the next step in your educational journey? We answer all of these questions and more.

[00:00:23] BHA: That's right, Brooke. Instead, many students and their families opt for high school learning that happens at home. I'm Becca Haupt Aldredge from Bucknell University. In this episode of College Admissions Insider, we're offering helpful insights for home-schooled students who are navigating the college process.

[00:26:34] BT: Yeah. It's the next big transition stage for everybody. Well, I think this has been a really awesome full episode of College Admissions Insider. Thanks to Ben for lending his insight into this really important topic.

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Identifying the onset of a depressive episode can be unnerving. Feeling panicked or anxious is an understandable reaction to the initial symptoms of depression. However, these reactions may contribute to low mood and worsen other symptoms, such as loss of appetite and disrupted sleep.

Anyone who has experienced depressive episodes before may wish to remind themselves that they can overcome these feelings again. They should focus on their strengths and on what they have learned from previous depressive episodes.

Accepting that a depressive episode may occur from time to time may help people deal with it when it does. It is important to remember that it is possible to manage symptoms with treatments, such as lifestyle changes, medication, and therapy.

Depressive episodes can often leave people focusing on the negatives and discounting the positives. To counteract this, people with depression can keep a positivity journal or gratitude journal. This type of journal helps to build self-esteem.

A person who is experiencing a depressive episode may have symptoms that include feelings of sadness, worthlessness, or hopelessness. They may also have low energy or fatigue, a loss of interest in activities once enjoyed, and more.

In this episode, we'll talk to librarians Jennifer Mincey and Todd Nuckolls, who are in charge of the college's archives, which are housed at the Scott Northern Wake Campus Library. Then, we'll delve into a discussion about one of our newest young adult books, "A Large Expanse of Sea" by Tahereh Mafi, with Library Technical Assistant and avid young adult literature reader Jasmine Smith. ff782bc1db