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Years of gender-based research have shown that in matters of the heart, sex differences abound. One striking example is the temporary heart condition known as takotsubo cardiomyopathy, also known as broken-heart syndrome.

The condition is usually the result of severe emotional or physical stress, such as a sudden illness, the loss of a loved one, a serious accident, or a natural disaster such as an earthquake. That's why the condition is also called stress-induced cardiomyopathy, or broken-heart syndrome.

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More than 90% of reported cases are in women ages 58 to 75. Research suggests that up to 5% of women suspected of having a heart attack actually have this disorder. Most people recover with no long-term heart damage.

The precise cause of broken heart syndrome isn't known, but experts think that surging stress hormones (for example, adrenaline) essentially "stun" the heart, triggering changes in heart muscle cells or coronary blood vessels (or both) that prevent the left ventricle from contracting effectively.

Most of the abnormalities in systolic function and ventricle wall movement seen in broken-heart syndrome clear up in one to four weeks. Most individuals who experience it recover fully within two months and are at low risk for it happening again.

There is no specific treatment for broken-heart syndrome. It depends on the severity of symptoms, and whether the person has low blood pressure or evidence of fluid backing up into the lungs. Clinicians often recommend standard heart failure medications such as beta blockers, ACE inhibitors, and diuretics (water pills). They may give aspirin to patients who also have atherosclerosis (plaque buildup in the arterial walls).

Takotsubo cardiomyopathy, also known as stress cardiomyopathy, apical ballooning syndrome, or broken heart syndrome, is a condition characterized by transient regional abnormal cardiac wall motion, not confined to a single coronary arterial territory.

After typing Edit Close Path. Do I hold the Shift key to select the right side of heart and then what? The other side of heart? Or the lightening bolt? Right now the image is all one piece. Do I need to hold the Shift key when selecting? What am I missing: DARN DARN DARN!

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To diagnose broken heart syndrome, a healthcare professional examines you and asks questions about your symptoms and medical history. You may be asked if you've had any major stresses recently, such as the death of a loved one.

Electrocardiogram (ECG or EKG). This quick test measures the electrical activity of the heart. Sticky patches called electrodes are placed on the chest and sometimes the arms and legs. Wires connect the electrodes to a computer, which shows the test results.

Coronary angiogram. This test checks for blockages in the heart arteries. It's done to rule out a heart attack. People with broken heart syndrome often don't have any blockages. A doctor inserts a long, thin flexible tube called a catheter into a blood vessel, usually in the groin or wrist. It's guided to the heart. Dye flows through the catheter to arteries in the heart. The dye helps the arteries show up more clearly on X-ray images and video.

Many people with broken heart syndrome are fully recovered within a month or so. An echocardiogram is done about 4 to 6 weeks after the first symptoms to make sure the heart is working better. Sometimes, broken heart syndrome happens again after treatment.

Once it's clear that broken heart syndrome is the cause of the symptoms, medicines may be given to reduce the strain on the heart. Medicines also can help prevent further episodes of broken heart syndrome.

Surgeries and procedures that are often used to treat a heart attack aren't helpful in treating broken heart syndrome. Such treatments open blocked arteries. Blocked arteries do not cause broken heart syndrome.

During its lifetime, Polar has had many accomplishments. Observations of energetic neutral atoms have provided the first-ever global images of substorm injections that are the sequence of events that lead to energetic auroral displays. These neutral atom images clearly show the broad extent in space of these energetic atoms and their instantaneous nature in time.

Feeling heartbroken from a recent breakup? Just believing you're doing something to help yourself get over your ex can influence brain regions associated with emotional regulation and lessen the perception of pain.

Inside a functional magnetic resonance imaging (fMRI) machine, the participants were shown images of their former partner and asked to recall the breakup. Then they were shown images of their friend. They were also subjected to physical pain (a hot stimulus on their left forearm).

This finding alone sends an important message to the heartbroken, said senior author Tor Wager, a professor of psychology and neuroscience at CU Boulder: "Know that your pain is real - neuro-chemically real."

Back inside the machine, the subjects were again shown images of their ex and subjected to pain. The placebo group not only felt less physical pain and felt better emotionally, but their brain responded differently when shown the ex.

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When you think of a broken heart, you may picture a cartoon drawing with a jagged line through it. But a real-life broken heart can lead to cardiac issues. Depression, mental health and heart disease have established ties. Read on for more information about how an extremely stressful event can have an impact on your heart.

Some signs and symptoms of broken heart syndrome differ from those of heart attack. In broken heart syndrome, symptoms occur suddenly after extreme emotional or physical stress. Here are some other differences:

If your health care professional thinks you have broken heart syndrome, you may need coronary angiography, a test that uses dye and special X-rays to show the inside of your coronary arteries. Other diagnostic tests are blood tests, EKG, echocardiography (a painless test that uses sound waves to create moving pictures of your heart) and cardiac MRI.

Our Advanced Heart Check begins with a 128-slice CT scan that provides enhanced 3-D views of the inner workings of your heart. This provides our expert cardiologists and radiologists the best means to diagnose any areas of concern.

Never has it been easier to rule out normal aches and pains and to fully understand if your heart is healthy. If you or someone you love have known risk factors for heart disease such as family history, obesity, stressed lifestyle, history of smoking or diabetes, the Advanced Heart Check is for you.

It sounds like science fiction, or science romantic-fiction. The 2004 movie Eternal Sunshine of the Spotless Mind often gets brought up, says Michelle Lonergan, now a postdoctoral fellow at the University of Ottawa who led the trial as part of her Ph.D. In the film, a couple, post-breakup, use a service to erase their memories of one another in response to the suffering of heartbreak.

In the Hopkins study, to be published in The New England Journal of Medicine online Feb. 10, the research team found that some people may respond to sudden, overwhelming emotional stress by releasing large amounts of catecholamines (notably adrenalin and noradrenalin, also called epinephrine and norepinephrine) into the blood stream, along with their breakdown products and small proteins produced by an excited nervous system. These chemicals can be temporarily toxic to the heart, effectively stunning the muscle and producing symptoms similar to a typical heart attack, including chest pain, fluid in the lungs, shortness of breath and heart failure.

The researchers collected detailed histories and conducted several tests, including blood work, echocardiograms, electrocardiograms, coronary angiograms, MRI scans and heart biopsies, on a total of 19 patients who came to Hopkins between November 1999 and September 2003. All had signs of an apparent heart attack immediately after some kind of sudden emotional stress, including news of a death, shock from a surprise party, fear of public speaking, armed robbery, a court appearance and a car accident. Eighteen of the stressed patients were female, between the age of 27 and 87, with a median age of 63. The results were then compared to seven other patients, all of whom had suffered classic, severe cases of heart attack, called a Killip class III myocardial infarction.

When results from both groups were compared, the researchers found that initial levels of catecholamines in the stress cardiomyopathy patients were two to three times the levels among patients with classic heart attack, and seven to 34 times normal levels.

Catecholamine metabolites, such as metanephrine and normetanephrine, were also massively elevated, as were other stress-related proteins, such as neuropeptide Y, brain natriuretic peptide and serotonin. These results provided added confirmation that the syndrome was stress induced. Heart biopsies also showed an injury pattern consistent with a high catecholamine state and not heart attack.

We overshare our heartbreak with friends, incessantly rehashing the details of the breakup until no one wants to hear about it anymore. We may be unable to stop crying about the breakup at work, even though we know how unprofessional it makes us look.

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