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This framework builds on the assessment of federal scientific integrity policies and practices described in the January 2022 report, Protecting the Integrity of Government Science, and draws from extensive input from federal agencies, as well as from across sectors, including academia, the scientific community, public interest groups, and industry. It has several key components that federal departments and agencies will use to improve scientific integrity policies and practices, including:

The framework requires all agencies to designate a scientific integrity official, and agencies that fund, conduct, or oversee research to designate a chief science officer, and it establishes the National Science and Technology Council (NSTC) Subcommittee on Scientific Integrity to oversee implementation of the framework, and evaluate agency progress.

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The framework was developed following a robust effort to study and improve scientific integrity policies and outcomes, and extensive engagement with stakeholders inside and outside of the federal government starting in May 2021. This process included engaging 30 federal agencies, and processing feedback from over 1,000 individuals and organizations through three listening sessions, three roundtables, and two requests for information.

Strong policies and effective practices protecting scientific integrity are essential for the development of evidence-based policies. By bolstering these policies and practices across the federal government, this first-of-its-kind framework will strengthen the ability of agencies and federal scientists to produce critical scientific information for evidence-based policymaking that can help make our nation healthier, safer, more prosperous, and more secure.

The .NET Framework (pronounced as "dot net") is a proprietary software framework developed by Microsoft that runs primarily on Microsoft Windows. It was the predominant implementation of the Common Language Infrastructure (CLI) until being superseded by the cross-platform .NET project. It includes a large class library called Framework Class Library (FCL) and provides language interoperability (each language can use code written in other languages) across several programming languages. Programs written for .NET Framework execute in a software environment (in contrast to a hardware environment) named the Common Language Runtime (CLR). The CLR is an application virtual machine that provides services such as security, memory management, and exception handling. As such, computer code written using .NET Framework is called "managed code". FCL and CLR together constitute the .NET Framework.

FCL provides the user interface, data access, database connectivity, cryptography, web application development, numeric algorithms, and network communications. Programmers produce software by combining their source code with .NET Framework and other libraries. The framework is intended to be used by most new applications created for the Windows platform. Microsoft also produces an integrated development environment for .NET software called Visual Studio.

In April 2019, Microsoft released .NET Framework 4.8, the last major version of the framework as a proprietary offering, followed by .NET Framework 4.8.1 in August 2022. Only monthly security and reliability bug fixes to that version have been released since then. No further changes to that version are planned. The .NET Framework will continue to be included with future releases of Windows and continue to receive security updates, with no plans to remove it as of November 2023.[3]

While Microsoft and their partners hold patents for CLI and C#, ECMA and ISO require that all patents essential to implementation be made available under "reasonable and non-discriminatory terms". The firms agreed to meet these terms, and to make the patents available royalty-free. However, this did not apply to the part of the .NET Framework not covered by ECMA-ISO standards, which included Windows Forms, ADO.NET, and ASP.NET. Patents that Microsoft holds in these areas may have deterred non-Microsoft implementations of the full framework.[8]

Common Language Infrastructure (CLI) provides a language-neutral platform for application development and execution. By implementing the core aspects of .NET Framework within the scope of CLI, these functions will not be tied to one language but will be available across the many languages supported by the framework.

Because computer systems commonly require interaction between newer and older applications, .NET Framework provides means to access functions implemented in newer and older programs that execute outside .NET environment. Access to Component Object Model (COM) components is provided in System.Runtime.InteropServices and System.EnterpriseServices namespaces of the framework. Access to other functions is via Platform Invocation Services (P/Invoke). Access to .NET functions from native applications is via the reverse P/Invoke function.

While Microsoft has never implemented the full framework on any system except Microsoft Windows, it has engineered the framework to be cross-platform,[23] and implementations are available for other operating systems (see Silverlight and Alternative implementations). Microsoft submitted the specifications for CLI (which includes the Base Class Libraries, CTS, and CIL),[24][25][26] C#,[5] and C++/CLI[27] to both Ecma International (ECMA) and International Organization for Standardization (ISO), making them available as official standards. This makes it possible for third parties to create compatible implementations of the framework and its languages on other platforms.

.NET Framework includes a garbage collector (GC) which runs periodically, on a separate thread from the application's thread, that enumerates all the unusable objects and reclaims the memory allocated to them. It is a non-deterministic, compacting, mark-and-sweep garbage collector. GC runs only when a set amount of memory has been used or there is enough pressure for memory on the system. Since it is not guaranteed when the conditions to reclaim memory are reached, GC runs are non-deterministic. Each .NET application has a set of roots, which are pointers to objects on the managed heap (managed objects). These include references to static objects, objects defined as local variables or method parameters currently in scope, and objects referred to by CPU registers.[30] When GC runs, it pauses the application and then, for each object referred to in the root, it recursively enumerates all the objects reachable from the root objects and marks them as reachable. It uses CLI metadata and reflection to discover the objects encapsulated by an object, and then recursively walk them. It then enumerates all the objects on the heap (which were initially allocated contiguously) using reflection. All objects not marked as reachable are garbage.[30] This is the mark phase.[31] Since the memory held by garbage is of no consequence, it is considered free space. However, this leaves chunks of free space between objects which were initially contiguous. The objects are then compacted together to make free space on the managed heap contiguous again.[30][31] Any reference to an object invalidated by moving the object is updated by GC to reflect the new location.[31] The application is resumed after garbage collection ends. The latest version of .NET framework uses concurrent garbage collection along with user code, making pauses unnoticeable, because it is done in the background.[32]

The garbage collector used by .NET Framework is also generational.[33] Objects are assigned a generation. Newly created objects are tagged Generation 0. Objects that survive one garbage collection are tagged Generation 1. Generation 1 objects that survive another collection are Generation 2. The framework uses up to Generation 2 objects.[33] Higher generation objects are garbage collected less often than lower generation objects. This raises the efficiency of garbage collection, as older objects tend to have longer lifetimes than newer objects.[33] By ignoring older objects in most collection runs, fewer checks and compaction operations are needed in total.[33]

.NET Framework was the predominant implementation of CLI, until the release of .NET. Other implementations for parts of the framework exist. Although the runtime engine is described by an ECMA-ISO specification, other implementations of it may be encumbered by patent issues; ISO standards may include the disclaimer, "Attention is drawn to the possibility that some of the elements of this document may be the subject of patent rights. ISO shall not be held responsible for identifying any or all such patent rights."[41] It is harder to develop alternatives to FCL, which is not described by an open standard and may be subject to copyright restrictions. Also, parts of FCL have Windows-specific functions and behavior, so implementation on non-Windows platforms can be problematic.

The MIT Framework creates a mechanism for ensuring scholarly research outputs are openly and equitably available to the broadest and most inclusive audience possible, while also providing valued services to our community. The vision we seek to advance through the application of this framework is one in which enduring, abundant, equitable, and meaningful access to scholarship serves to empower and inspire humanity.

In this guidance, we provide a framework for analyzing whether a digital asset is an investment contract and whether offers and sales of a digital asset are securities transactions. As noted above, under the Howey test, an "investment contract" exists when there is the investment of money in a common enterprise with a reasonable expectation of profits to be derived from the efforts of others. Whether a particular digital asset at the time of its offer or sale satisfies the Howey test depends on the specific facts and circumstances. We address each of the elements of the Howey test below. ff782bc1db