The purpose of this randomized, placebo-controlled, blind study was to investigate the effects of the drinkable nutraceutical ELASTEN (QUIRIS Healthcare, Gtersloh, Germany) on skin aging and skin health. Drinking ampoules provides a blend of 2.5 g of collagen peptides, acerola fruit extract, vitamin C, zinc, biotin, and a native vitamin E complex. This controlled interventional trial was performed on 72 healthy women aged 35 years or older. They received either the food supplement (n = 36) or a placebo (n = 36) for twelve weeks. A skin assessment was carried out and based on objective validated methods, including corneometry (skin hydration), cutometry (elasticity), the use of silicon skin replicas with optical 3D phase-shift rapid in-vivo measurements (PRIMOS) (roughness), and skin sonography (density). The verum group was followed for an additional four weeks (without intake of the test product) to evaluate the sustainability of the changes induced by the intake of the test product. The test product significantly improved skin hydration, elasticity, roughness, and density. The differences between the verum group and the placebo group were statistically significant for all test parameters. These positive effects were substantially retained during the follow-up. The measured effects were fully consistent with the subjective assessments of the study participants. The nutraceutical was well tolerated.

Hydration refers to the amount of water in the body, and maintaining normal hydration for our feline friends (and for ourselves!) is essential for a variety of vital bodily functions, including temperature regulation, maintenance of normal electrolyte concentrations, digestion of food, lubrication of joints, and delivery of oxygen and other nutrients to the organs of the body.


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From a basic perspective, the amount of water in the body is a function of how much is taken in in and how much is excreted. Water is taken into the body by drinking and via the water content in food and is lost in the form of urine, feces, bile, sweat, and humidity in exhaled breath. Any condition in which water intake is decreased and/or water loss is increased (or some combination of these two) can predispose to dehydration, with which total body water is decreased.

Dehydration can cause a number of health problems, including decreased circulation leading to multi-organ dysfunction, an inability to control body temperature, cardiac arrhythmias, and neurologic dysfunction, to name a few. Clearly, helping cats avoid becoming dehydrated is a very important aspect of their health maintenance, and being aware of how we can do this is a vital component of our being good stewards of their well-being.

The most common causes of dehydration in cats are diseases that cause increased water loss. Chronic kidney disease, diabetes, vomiting, diarrhea, and hyperthyroidism all fall into this category. Increased water loss can also be caused by some medications, including diuretics that are commonly used to treat heart disease. Cats can experience decreased water intake due to weakness/lethargy, decreased appetite, hesitation to drink as a result of dental problems, and lack of access to water bowls due to either owner failure to provide water (or outdoor lifestyle with no access to water) or territorial conflicts among cats in a household.

If you are concerned that your cat is dehydrated, you should contact a veterinarian promptly. Dehydration can be addressed in the veterinary clinical setting by either intravenous or subcutaneous fluid therapy, and restoring normal hydration is often a major treatment goal in cats that are diagnosed with a variety of diseases. Of course, determining why a cat is dehydrated is another very important aspect of providing optimal veterinary care.

What we do know, says Hew-Butler, is that water is essential for our bodies. It makes up a majority of our cells and blood, flushes out waste through our urine and helps cool our bodies through sweat. Too little water, and our cells shrivel up from dehydration. Too much water, and our cells swell up from hyponatremia.

Hew-Butler says hydration is also about the balance of water to salt. Sodium is necessary for our nerves and muscles to function. And it's what our body uses to regulate the amount of fluid it needs to stay hydrated.

Another persistent myth about hydration states that caffeine is a diuretic that makes you pee, and therefore caffeinated drinks like coffee and tea don't hydrate your body. The idea is based on the findings of a study from 1928 that looked at three people. Not only is that sample incredibly small by today's standards, but the finding has not held up to more recent experiments. So consider this myth busted.

According to multiple studies, ranging from a 2003 review of research dating back to 1966 to a 2014 clinical trial that compared coffee to water ingestion in 50 men, caffeine can be a mild diuretic in large amounts for people who aren't accustomed to it. But caffeinated drinks consumed in moderation provide the same hydration as non-caffeinated drinks.

Essentially, with the exception of higher alcohol-content beverages like hard liquor, all liquids count towards hydration. As does food. The experts we spoke to say about 20% of your fluid intake comes from the food you eat, from fruits and vegetables to pasta.

Scientists commonly measure dehydration by looking at the concentration of sodium and other solids in urine, which is what makes pee darker in color. But that isn't the most precise way to tell whether someone needs more water, says Hew-Butler.

Objective:  This study investigated the effects of 13 different commonly consumed drinks on urine output and fluid balance when ingested in a euhydrated state, with a view to establishing a beverage hydration index (BHI), i.e., the volume of urine produced after drinking expressed relative to a standard treatment (still water) for each beverage.

Results:  Total urine masses (mean  SD) over 4 h were smaller than the still-water control (1337  330 g) after an oral rehydration solution (ORS) (1038  333 g, P < 0.001), full-fat milk (1052  267 g, P < 0.001), and skimmed milk (1049  334 g, P < 0.001). Cumulative urine output at 4 h after ingestion of cola, diet cola, hot tea, iced tea, coffee, lager, orange juice, sparkling water, and a sports drink were not different from the response to water ingestion. The mean BHI at 2 h was 1.54  0.74 for the ORS, 1.50  0.58 for full-fat milk, and 1.58  0.60 for skimmed milk.

Conclusions:  BHI may be a useful measure to identify the short-term hydration potential of different beverages when ingested in a euhydrated state. This trial was registered at www.isrctn.com as ISRCTN13014105.

Monitoring hydration status before, during and after exercise is essential for both performance and safety during physical activity. Maintaining an appropriate level of hydration (a euhydrated state) has been shown to increase performance (aerobic exercise, anaerobic exercise, strength, power), allows athletes to exercise at lower body temperatures and heart rates, improves cognitive function, and has been shown to enhance immunological function.

Dehydration is influenced by exercise intensity, environmental conditions (temperature and humidity), and availability of fluids during exercise. Once an individual loses 2% of their body mass from fluid losses impairments in performance are noticeable and these impairments become more extreme with greater levels of dehydration. Also, it has been shown that with increasing levels of dehydration body temperature and heart rate increases over and above the levels of someone who is hydrated, which can increase the risk of heat illness in dehydrated exercising individuals.

An appropriate hydration strategy involves athletes to begin exercise hydrated, minimize fluid losses during exercise, and then replace fluid losses after exercise. Hydration needs are individualistic, so athletes should be aware of their own hydration needs to maximize performance and safety.

As seen in the Venn diagram above not one biomarker of hydration (weight, urine, and thirst), provides enough evidence of dehydration; however, the combination of any two simple self-assessment markers means dehydration is likely, and the presence of all three makes dehydration very likely.

Rehydration should occur within 2 hours post exercise to assure optimal rehydration. Post exercise rehydration should be 150% of body mass loss during exercise. Use this calculation to adequately replace fluid post exercise, following the guidelines stated previously

The first step to ensure athletes do not become dehydrated is to have the proper supplies in place. The following are KSI-suggested items to have on hand to promote hydration during sports activities. Names of common brands and retailers are provided as examples, however this is not an exhaustive list by any means. Prices are approximate and many providers offer discounted rates for large orders.

Our hydration system features 4 delicious flavors - in a convenient 8-serving pouch. Our two pre-exercise and two performance blends are designed to help athletes maintain energy & electrolyte balance during exercise.

Vomiting, diarrhea, and fever cause the body to lose water quickly and are common causes of dehydration. Luckily, most healthy adults can easily rehydrate by consistently drinking lots of water and fluids high in electrolytes.

People may not know if they need more hydration or moisture in their skin care routine, but this is not always necessary when choosing products. The American Academy of Dermatology Association (AADA) recommends that people pick products formulated for their skin type, such as dry or oily.

Among the three types of ingredients, there is some overlap in the type of skin they benefit. A dermatologist can sort this out and tell people if their skin requires more moisture, hydration, or both. These professionals can also provide suggestions for specific products that address these needs. e24fc04721

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