Mission of the DeciphGYG
Mission of the DeciphGYG
The DeciphGYG project is focused on elucidating the machinery of human glycogenin 1 (hGYG1) in glycogenesis using MD and QM/MM approaches
Elucidate the molecular details of the recognition of the glucose donor and acceptors by hGYG1
Decipher the catalytic mechanisms of glucosyl transfer catalyzed by hGYG1 and proposed mutants.
Investigate the influence of the T83M mutation on the catalysis and dynamics of the lid of hGYG1.