Co-crystallisation

I first learnt about crystallisation as a method of purification. It is now a common crystal engineering strategy to try to make multi-component crystals, where molecules don't separate upon crystallisation, but form ordered structures containing two or more distinct molecules. We work in this area of co-crystallisation, seeing how computational methods can be used to understand when molecules want to crystallise together, and how this influences the materials propoerties.

Undestanding the formation of apremilast cocrystals

Marta K. Dudek, Ewelina Wielgus, Piotr Paluch, Justyna Sniechowska, Maciej Kostrzewa, Graeme M. Day, Grzegorz D. Bujacz and Marek J. Potrzebowski

Acta Crystallographica B, accepted for publication (2019)

Luc M. LeBlanc, Stephen G. Dale, Christopher R. Taylor, Axel D. Becke, Graeme M. Day and Erin R. Johnson

Angewandte Chemie International Edition, 57, p.14906-14910 (2018)

Emily N. Pinter, Lee S. Cantrell, Graeme M. Day, Kraig A. Wheeler

CrystEngComm, 20, p.4213-4220 (2018)

Christopher R. Taylor and Graeme M. Day

Crystal Growth & Design, 18, 892-904 (2018)

A. G. Slater, M. A. Little, A. Pulido, S. Y. Chong, D. Holden, L. Chen, C. Morgan, X. Wu, G. Cheng, R. Clowes, M. E. Briggs, T. Hasell, K. E. Jelfs, G. M. Day and A. I. Cooper

Nature Chemistry, 9, 17-25 (2017)

Kreshnik Hoxha, David H. Case, G. M. Day and Timothy J. Prior

CrystEngComm, 17, 7130-7141 (2015)

D.-K. Bucar, G. M. Day, I. Halasz, G. G. Z. Zhang, J. R. G. Sander, D. G. Reid, L. R. G. MacGillivray, M. J. Duer and W. Jones

Chemical Science, 4, 4417-4425 (2013)

Selected as a HOT article and highlighted in Chemistry World.

M. D. Eddleston, B. Patel, G. M. Day and W. Jones

Crystal Growth & Design, 13, 4599-4606 (2013)

J. Garcera, T. Friscic, K. E. Hejczyk, L. Fabian, S. M. Clarke, G. M. Day, E. Molins, W. Jones

CrystEngComm, 14, 7898-7906 (2012)

D. Yan, A. Delori, G. Lloyd, B. Patel, T. Friscic, G. M. Day, D.-K. Bucar, W. Jones, J. Lu, M. Wei, D. G. Evans, X. Duan

CrystEngComm, 14, 5121-5123 (2012)

D. Yan, A. Delori, G. O. Lloyd, T. Friscic, G. M. Day, W. Jones, J. Lu, M. Wei, D. G. Evans and X. Duan

Angewandte Chemie international edition, 50, 12483-12486 (2011)

J. T. A. Jones, T. Hasell, X. Wu, J. Bacsa, K. E. Jelfs, M. Schmidtmann, S. Y. Chong, D. J. Adams, A. Trewin, F. Schiffman, F. Cora, B. Slater, A. Steiner, G. M. Day and A. I. Cooper

Nature, 474, 367-371 (2011)

A. J. Cruz-Cabeza, G. M. Day and W. Jones

Physical Chemistry Chemical Physics, 13, 12808-12816 (2011)

A. J. Cruz-Cabeza, S. Karki, L. Fabian, T. Friscic, G. M. Day and W. Jones

Chemical Communications, 46, 2224-2226 (2010)

S. Karki, T. Friscic, L. Fabian, P. R. Laity, G. M. Day and W. Jones

Advanced Materials, 21, 3905-3909 (2009)

A. J. Cruz-Cabeza, G. M. Day and W. Jones

Chemistry - A European Journa, 14, 8830-8836 (2008)

K. L. Nguyen, T. Friscic, G. M. Day, L. F. Gladden and W. Jones

Nature Materials, 6, p.206-209 (2007)

A. J. Cruz Cabeza, G. M. Day, W. D. S. Motherwell and W. Jones

Journal of the American Chemical Society, 128 (45), p.14466-14467 (2006)