Cyber-Physical Systems (CPSs) refer to systems comprising of software components, physical components and social entities which monitor, control, and coordinate processes within a physical environment. CPSs apply to a wide range of mission-critical applications that span from the intelligent management of logistics in complex supply chains,  advanced manufacturing  systems and smart contracts, all the way to autonomous systems, and systems that support the smart interactions between humans and machines (M2H), or between machines (M2M). The workshop aims to bring together leading researchers, experts from software and hardware companies, as well as a network of technology leaders to discuss and debate  various topics of Software Development of Cyber-Physical Systems related to Requirements Elicitation, Modeling and Analysis of CPSs, DevOps and Continuous Development and Evolution for CPSs, Scalable Architectures for Efficient Deployment and Complexity Management, Adaptation, Performance and Control, Security Frameworks for CPSs, and Run-time Operation Frameworks and Data Management for CPSs