COVID-19 in Pregnancy:
Summary of Clinical Guidelines and Relevant Research Studies
This website is designed to provide perinatal clinicians and scientists with a succinct and up-to-date collation of relevant peer-reviewed literature and clinical guidance regarding COVID-19 and pregnancy.
AJOG. Clinical characteristics of 46 Pregnant Women with a SARS-CoV-2 Infection in Washington State. [5/18/20]
15% of patients developed severe illness, largely in overweight or obese women with underlying chronic medical conditions. There was one term IUFD of unknown etiology, autopsy and placental pathology negative for SARS-CoV-2 infection.
AJOG MFM. Vertical transmission of COVID-19: SARS-CoV-2 RNA on the fetal side of the placenta in pregnancies with COVID-19 positive mothers and neonates at birth. [5/14/20]
Detection of SARS-CoV-2 RNA in placental samples of COVID-19 positive patients whose neonates also tested positive at birth, raising the possibility of vertical transmission.
Obstet & Gynecol. A Postpartum Death Due to COVID-19 in the United States. [5/11/20]
Case of a pregnant patient who presented with 7 days of vague complaints, delivered, and experienced rapid deterioration within 36 hours.
AJOG MFM. Clinical course of severe and critical COVID-19 in hospitalized pregnancies: a US cohort study. [5/10/20]
Cohort of 64 pregnant patients from 12 institutions with severe or critical COVID-19 describes median duration of hospitalization of 6 days, characteristics of respiratory illness, and 75% rate of preterm birth in those with critical illness (largely iatrogenic).
IDSA: Infectious Diseases Society of America Guidelines on the Diagnosis of COVID-19 [5/6/20]
Recommendations for use of nucleic acid testing for SARS-CoV-2, who to test, and prioritization of testing.
SMFM: Management Considerations for Pregnant Patients With COVID-19 [updated 4/30/20]
Recommendations for inpatient and outpatient management of COVID-19 in pregnancy.