Complement MASP-2

MASP-2 is an enzyme encoded by the MASP2 gene in humans and it participates in the complement system. Uncontrolled or inappropriate activation of the complement system can lead to diseases with severe tissue damage. Inhibition of MASP-2 does not interfere with the classical antibody-dependent complement activation pathway and thus may serve as a key component of therapeutic development.  Learn more: Complement MASP-2