Research

The role of chaotic vasomotion

Vasomotion refers to the spontaneous rhythmic contraction and dilation of blood vessels observed in many vascular bed. We hypothesize that:

• • • • Vasomotors form a chemical network

      • Elements of this network interact to produce desynchronized activity

      • Chaotic, desynchronized vasomotion enhances oxygenation in skeletal muscle

• R.K Pradhan, V.S.Chakravarthy, A. Prabhakar, Effect of Chaotic Vasomotion in Skeletal Muscle on Tissue oxygenation , Microvascular Research,Vol 74/1,pp 51-64, July 2007.

• R.K. Pradhan, V. S. Chakravarthy. A computational Model that Links Nonperiodic Vaosomotion to Enhanced Oxygenation in Skeletal Muscle. Mathematical Biosciences, 209 (2), p.486-499, Oct 2007.

• R.K. Pradhan, V. S. Chakravarthy, Desynchronized Vasomotion and Desynchronized Fiber Activation Pattern Enhance Oxygenation in a Model of Skeletal Muscle, Jnl of Theoretical Biology, Vol.  259, No. 2., 21 July 2009, pp. 242-252. 

• Ranjan K. Pradhan and V. S. Chakravarthy, Informational dynamics of Vasomotion in Microvascular Networks: A Review, Acta Physiologica (Oxf). 201(2):193-218, Feb, 2011.