List of Publication (Google Scholar Citation)

1. Tsai MC, Chen ML and Lai C-C. Does the non-uniform degree of blockade of alpha-bungarotoxin interfere with its effect on post-tetanic potentiation of twitch tension. Asia Pac J Pharmacol. 1988;3:29-32.

2. Tsai MC, Lai C-C and Chen ML. Mode of action of tobramycin on the neuromuscular transmission in the mouse diaphragm preparation. Asia Pac J Pharmacol. 1988;3:167-175.

3. Lai C-C, Chiu TH, Rosenberg HC and Huang WH. Improved proteinase K digestion for the rapid isolation of mRNA from mammalian tissues. BioTechniques. 1993;15:620-626.

4. Lai C-C, Andrus PK and Chiu TH. Hydroxyl radical generation and nitric oxide synthase activity activity in Fisher 344x Brown-Norway F1 rat brain. Neurosci Lett. 1994;179:37-40.

5. Lai C-C, Huang WH, Askari A, Wang Y, Sarvazyan N, Klevay LM and Chiu TH. Differential regulation of superoxide dismutase in copper-deficient rat organs. Free Radic Biol Med. 1994;16:613-620.

6. Huang W-H, Lai C-C, Wang Y, Askari A, Klevay LM, Askari A and Chiu TH. Altered expression of cardiac Na+,K+-ATPase isoforms in copper-deficient rats. Cardiovasc Res. 1995;29:563-568.

7. Lai C-C, Huang W, Askari A, Klevay LM and Chiu TH. Expression of glutathione peroxidase and catalase in copper-deficient rat liver and heart. J Nutr Biochem. 1995;6:256-262.

8. Dun NJ, Dun SL, Huang RL, Dun EC, Lai C-C, Wong PYD and Forstermann U. Distribution and origin of nitric oxide synthase-immunoreactive nerve fibers in the rat epididymis. Brain Res. 1996;738:292-300.

9. Lai C-C, Huang WH, Klevay LM, Gunning III WT and Chiu TH. Antioxidant enzyme gene transcription in copper-deficient rat liver. Free Radic Biol Med. 1996;212:233-240.

10. Lai C-C, Peng M, Huang WH and Chiu TH. Chronic exposure of cardiac myocytes to hydrogen peroxide selectively enhances the expression of catalase. J Mol Cell Cardiol. 1996;28:1157-1163.

11. Lai C-C, Wu SY, Dun SL and Dun NJ. Nociceptin-like immunoreactivity in the rat dorsal horn and inhibition of substantia gelatinosa neurons. Neuroscience. 1997;814:887-891.

12. Lai C-C, Wu SY, Lin HH and Dun NJ. Excitatory action of pituitary adenylate cyclase activating polypeptide on rat sympathetic preganglionic neurons in vivo and in vitro. Brain Res. 1997;748:189-194.

13. Lin HH, Wu SY, Lai C-C and Dun NJ. GABA- and Glycine-mediated inhibitory postsynaptic potentials in neonatal rat rostral ventrolateral medulla neurons in vitro. Neuroscience. 1998;822:429-442.

14. Lai C-C, Wu SY, Chen C-T and Dun NJ. Nociceptin inhibits rat sympathetic preganglionic neurons in situ and in vitro. Am J Physiol Regulatory Integrative Comp Physiol. 2000;278:R592-R597.

15. Brailoiu GC, Lai C-C, Chen CT, L. HL, Lin HH and Dun NJ. Sympathoinhibitory action of nociceptin in the rat spinal cord. Clin Exp Pharmacol Physiol. 2002;293:233-237.

16. Lai C-C, Lin HH, Chen C-W, Chen S-H and Chiu TH. Excitatory action of lead on rat sympathetic preganglionic neurons in vitro and in vivo. Life Sci. 2002;71:1035-1045.

17. Huang S-Y, Fu S-H, Lai C-C and Chen H-H. Effects of fermented soyben extract on antioxidant enzymes in rat liver, kidney and brain. Tzu-Chi Med J. 2003;15:105-112.

18. Lin HH, Chen C-H, Hsieh W-K, Chiu TH and Lai C-C*. Hydrogen peroxide increases the activity of rat sympathetic preganglionic neurons in vivo and in vitro. Neuroscience. 2003;1213:641-647.

19. Lin HH, Hsieh W-K, Shiu J-Y, Chiu TH and Lai C-C*. Inhibition by ethanol of NMDA-induced responses and acute tolerance to the inhibition in rat sympathetic preganglionic neurons in vitro and in vivo. Br J Pharmacol. 2003;1405:955-963.

20. Hu CC, Hsiao CH, Huang SY, Fu SH, Lai C-C, Hong TM, Chen HH and Lu FJ. Antioxidant activity of fermented soybean extract. J Agric Food Chem. 2004;5218:5735-5739.

21. Lai C-C, Chang M-C and Lin HH. Acute tolerance to ethanol Inhibition of NMDA-induced responses in rat rostral ventrolateral medulla neurons. J Biomed Sci. 2004;11:482-492.

22. Lin HH, Chiu H-Y and Lai C-C*. Potentiation of spinal N-methyl-D-aspartate-mediated nociceptive transmission by cocaine-regulated and amphetamine-regulated transcript peptide in rats. NeuroReport. 2005;16:253-257.

23. Scruggs P, Lai C-C, Scruggs JE and Dun NJ. Cocaine- and amphetamine-regulated transcript peptide potentiates spinal glutamatergic sympathoexcitation in anesthetized rats. Regul Pept. 2005;127:79-85.

24. Lin HH, Chang S-J, Shie H-J and Lai C-C*. Ethanol inhibition of NMDA-induced responses and acute tolerance to the inhibition in rat rostral ventrolateral medulla in vivo: involvement of cAMP-dependent protein kinases. Neuropharmacology. 2006;514:747-755.

25. Dun SL, Brailoiu E, Hsieh W-K, Lai C-C, Yang J, Chang JK and Dun NJ. Expression and activity of cocaine-and amphetamine-regulated transcript peptide1-39 in the rat. Regul Pept. 2007;140:47-54.

26. Lai C-C, Kuo T-I and Lin HH. The Role of protein kinase A in acute ethanol-induced neurobehavioral actions in rats. Anesth Analg. 2007;1051:89-96.

27. Chiu H-Y, Lin H-H and Lai C-C*. Potentiation of spinal NMDA-mediated nociception by cocaine- and amphetamine-regulated transcript peptide via PKA and PKC signaling pathways in rats. Regul Pept. 2009;1581-3:77-85.

28. Hsieh W-K, Lin H-H and Lai C-C*. Involvement of protein kinase C and Src tyrosine kinase in acute tolerance to ethanol inhibition of spinal NMDA-induced pressor responses in rats. Br J Pharmacol. 2009;1583:806-818.

29. Chiu H-Y, Lin H-H and Lai C-C*. Cocaine- and amphetamine-regulated transcript (CART) peptide activates ERK pathways via NMDA receptors in rat spinal cord dorsal horn in an age-dependent manner. Regul Pept. 2010;164:90-96.

30. Keng N-T, Lin H-H, Hsieh W-K, Lin H-R and Lai C-C*. Dual regulation by ethanol of the inhibitory effects of ketamine on spinal NMDA-induced pressor responses in rats. J Biomed Sci. 2012;19:11.

31. Situmorang JH, Lin HH, Lo H and Lai CC*. Role of neuronal nitric oxide synthase (nNOS) at medulla in tachycardia induced by repeated administration of ethanol in conscious rats. J Biomed Sci. 2018;25:8.

32. Lo H, Lin HH, Chen JK, Stiumorang JH and Lai CC*. Involvement of NMDA receptors, nitric oxide and GABA in rostral ventrolateral medulla in acute ethanol-induced cardiovascular responses in rats. Alcohol Clin Exp Res. 2018;42(8):1418-1430

33. Lin HH, Cheng TT, Lo H, Lin YC and Lai CC*. Spontaneously hypertensive rats exhibit higher sensitivity to ethanol-induced hypotensive effects: role of NMDA receptors and nitric oxide in rostral ventrolateral medulla. Alcohol. 2018;73:25-35.

34. Lai CC, Yuan, ZF, Chu, LY, Chuang, KT and Lin, HH. Roles of cocaine- and amphetamine-regulated transcript peptide in the rostral ventrolateral medulla in cardiovascular regulation in rats. Brain Res. 2019;1710:117-124.

35. Lai CC, Lo H, Lin HG and Lin HH. Potentiation of NMDA-mediated responses by amyloid beta-peptide 1-40 in rat sympathetic preganglionic neurons. J Alzheimers Dis. 2019;67:1291-1303.

36. Lai CC, Hsu JW, Cheng YS and Lin HH*. Involvement of metabotropic glutamate receptor 5 in ethanol regulation of NMDA receptor activity in rat substantia gelatinosa neurons.Life Sci. 2019;233:116729

37. Lai CC, Fang C, Kuo CY, Wu YW and Lin HH*. Activation of mGluR5 and NMDA Receptor Pathways in the Rostral Ventrolateral Medulla as a Central Mechanism for Methamphetamine-Induced Pressor Effect in Rats.Biomolecules 2020;10:149; doi:10.3390/biom100101499.

38. Situmorang JH, Lin HH, Islam MS and Lai CC*. Ovariectomy Exacerbates Acute Ethanol-Induced Tachycardia:  Role of Nitric Oxide and NMDA Receptors in the rostral ventrolateral medulla. Int. J. Mol. Sci. 2023; 24, 5087. 

39. Islam, M.S., Lai, C.C., Wang, L.H. & Lin, H.H. Inhibition of NMDA Receptor Activation in the Rostral Ventrolateral Medulla by Amyloid-β Peptide in Rats. Biomolecules 2023: 13, 1736; doi:10.3390/biom13121736. 

List of Poster

1. Lai C-C, Wang Y, Sarvazyan N, et al. Cu/Zn superoxide dismutase (Cu/Zn-SOD) in copper deficient rats. FASEB Journal 1993; 7:A658.

2. Lai C-C, Huang WH, Askari A, Klevay LM, Chiu TH. Regulation of catalase (CAT) and glutathione peroxidase (GPX) in copper-deficient rat liver and heart. FASEB Journal 1994; 8:A677.

3. Lai C-C, Huang WH, Klevay LM, Chiu TH. Increased nuclear iron content and changes in transcriptional rates for Mn-SOD and catalase in copper deficient rat liver. FASEB Journal 1995; 9:A1349-A.

4. Dun SL, Lai C-C, Wu S, Dun NJ, Saria A, Fischer-Colbrie R. Distribution of secretoneurin-like immunoreactivity in the rat autonomic ganglia. Abstr. Soc. Neurosci. 1996; 22:2002.

5. Lin HH, Lai C-C, Dun SL, Dun NJ. Detection and possible function of pituitary adenylate cyclase activating polypeptide in the rat spinal sympathetic nuclei. Abstr. Soc. Neurosci. 1996; 22:392.

6. Lai C-C, Wu S, Dun SL, Dun NJ. Detection of nociceptin-immunoreactivity in rat sympathetic nuclei and inhibition of sympathetic preganglionic neurons in vivo and in vitro. Abstr. Soc. Neurosci. 1997; 23:1519.

7. Lai C-C, Lin HH. Effects of hydrogen peroxide on rat sympathetic neurons in vivo. The Fourteenth Joint Annual Conference of Biomedical Science 1999 :P87.

8. Chen CW, Lai C-C, Chen HH, Chiu TH. Excitatory action of lead on rat sympathetic preganglionic neurons (SPNs) in vivo. The Fifteenth Joint Annual Conference of Biomedical Science 2000 :P207.

9. Lai C-C, Lin HH, Chen SH, Chiu TH. Inhibitory action of oxygen radicals on rat substantia gelatinosa neurons. The Fifteenth Joint Annual Conference of Biomedical Science 2000 :P330.

10. Chen C-H, Lin HH, Lai C-C. Effect of CART peptide on rat sympathetic preganglionic neurons in vivo. The Sixteenth Joint Annual Conference of Biomedical Science 2001 :P219.

11. Chen H-H, Fu S-H, Lai C-C. Trichloroethylene and perchloroethylene alter antioxidant enzymes in mice. The 9th SCBA International Symposium 2001 :POS9-A-12.

12. Chen K-H, Chen SH, Lai C-C. Effects of peroxides on rat substantia gelatinosa neurons. The Sixteenth Joint Annual Conference of Biomedical Science 2001 :P207.

13. Fu SH, Lai C-C, Chen HH. Effects of trichloroethylene and perchloroethylene on antioxidant enzymes in mice. The Sixteenth Joint Annual Conference of Biomedical Science 2001 :P346.

14. Lin H-H, Lai C-C. Effects of acute alcohol exposure on neurotransmission in rat rostral ventrolateral medulla neurons in vitro. The 9th SCBA International Symposium 2001 :POS18-B-8.

15. Shiu J-Y, Lin HH, Lai C-C. Acute tolerance to ethanol inhibition of NMDA-induced depolarization in rat sympathetic preganglionic neurons in vitro. The Seventeenth Joint Annual Conference of Biomedical Science 2002 :P245.

16. Hsieh W-K, Chiu TH, Lai C-C. Inhibition by ethanol of NMDA-induced responses and development of tolerance to the inhibition in sympathetic preganglionic neurons of rats in vivo. The Eighteenth Joint Annual Conference of Biomedical Science 2003 :P257.

17. Jang M-C, Lin HH, Lai C-C. Effects of ethanol on glutamate receptors in rat rostral ventrolateral medulla neurons in vivo. The Eighteenth Joint Annual Conference of Biomedical Science 2003 :P255.

18. Chiu HY, Lai C-C. Enhancement of NMDA-mediated nociceptive transmission by CART peptide in rat spinal cord. The Nineteenth Joint Annual Conference of Biomedical Science 2004 :P378.

19. Shie H-J, Lin HH, Lai C-C. Protein kinase A inhibitors decreased ethanol inhibition of NMDA-induced pressor effects in rat rostral ventrolateral medulla. The Nineteenth Joint Annual Conference of Biomedical Science 2004 :P373.

20. Chuang H-T, Hsieh W-K, Cheng Y-S, Lai C-C. Regulation by protein phosphorylation of ethanol inhibition of NMDA-induced responses in rat sympathetic preganglionic neurons. The Twentieth Joint Annual Conference of Biomedical Science 2005 :P435.

21. Kao T-I, Chang S-J, Lin HH, Lai C-C. Intracerebroventricular (ICV) injection of protein kinase A inhibitor blocked ethanol- induced behavioral changes in rats. The Twentieth Joint Annual Conference of Biomedical Science 2005 :P436.

22. Keng N-T, Lin HH, Lai C-C. Synergistic effects of ethanol and ketamine on NMDA-induced responses in rat spinal cord. The Twentieth Joint Annual Conference of Biomedical Science 2005 :P455.

23. Lai C-C, Hsieh W-K, Chuang H-T. Ethanol inhibition of NMDA - induced responses in rat sympathetic preganglionic neurons: regulation by protein phosphorylation. Washington, DC: Society for Neuroscience 2005 :Program No. 797.10.

24. Lai C-C, Shie H-J, Lin HH. Protein kinase A regulates ethanol inhibition of N - methyl - d - aspartate - induced responses in rat rostral ventrolateral medulla. Washington, DC: Society for Neuroscience 2005 :Program No. 797.5.

25. Chang C-Y, Chiu H-Y, Lai C-C, Lin H-H. CART peptide potentiation of NMDA-mediated depolarization is reduced by a protein kinase A inhibitor in rat dorsal horn neurons. The 21th Joint Annual Conference of Biomedical Science 2006 :P392.

26. Chang S-L, Lin HH, Lai C-C. The involvement of protein kinase A in acute tolerance to ethanol inhibition of NMDA-induced pressor effects in rostral ventrolateral medulla of rats. The 21th Joint Annual Conference of Biomedical Science 2006 :P365.

27. Cheng Y-S, Lai C-C. Ethanol inhibition of substantia gelatinosa neurons in rat spinal cord. The 21th Joint Annual Conference of Biomedical Science 2006 :P558.

28. Keng NT, Lin HH, Lai C-C. Interaction of ethanol with NMDA receptor antagonists on spinal NMDA-induced pressor responses in rats. The 22nd Joint Annual Conference of Biomedical Science 2007 :P208.

29. Lai C-C. Potentiation of NMDA-induced responses by CART peptides in rat dorsal horn neurons: Involvement of protein kinase A. San Diego, CA: Society for Neuroscience 2007; Program No. 576.11.

30. Lai Y-C, Lai C-C. Ethanol and butanol inhibition of NMDA-induced responses in rat sympathetic preganglionic neurons: Role of magnesium ion. The 22nd Joint Annual Conference of Biomedical Science 2007 :P413.

31. Leu S-Y, Huang Y-S, Lai C-C, Lin H-H. Cardiovascular responses to microinjection of CART peptide into the RVLM of anesthetized rats. The 22nd Joint Annual Conference of Biomedical Science 2007 :P442.

32. Wu Y-W, Lai C-C. Ethanol regulation of the phosphorylation of NMDA receptor NR1 subunit in rat rostral ventrolateral medulla. 7th IBRO World Congress of Neuroscience 2007 :POS-FRI-178.

33. Lai C-C, Wu Y-W. Ethanol-induced phosphorylation of NMDA receptor NR1 subunit in rat rostral ventrolateral medulla: role in ethanol-induced changes in blood pressure. FENS Abstr. 2008; 4:194.7.

34. Lin H-G, Lin H-H, Lai C-C. Effects of amyloid beta-peptides on neurotransmitter receptor activations in rat sympathetic preganglionic neurons. The 23rd Joint Annual Conference of Biomedical Science 2008 :P309.

35. Chen Y-C, Lai C-C. Radiotelemetric evaluation of the cardiovascular effects of subacute ethanol administration in rats. The 24th Joint Annual Conference of Biomedical Science 2009 :P236.

36. Huang Y-S, Lai C-C. Potentiation of NMDA-mediated responses by amyloid beta-peptide 1-40 in rat rostral ventrolateral medulla in vivo. The 24th Joint Annual Conference of Biomedical Science 2009 :P239.

37. Lai C-C, Lin H-G, Lo H, Lin H-H. Potentiation of NMDA Receptor Function by Amyloid Beta-Peptide in Rat Sympathetic Preganglionic Neurons. 36th International Congress of Physiological Sciences 2009 :P5AM-1-3

38. Hsieh M-C, Lai C-C. Differential effect of ethanol on pressor responses induced by NMDA microinjected into rostral ventrolateral medulla in normotensive and spontaneously hypertension rats. The 25th Joint Annual Conference of Biomedical Science 2010 :P359.

39. Hsieh W-K, Lin H-H, Lai C-C. Involvement of metabotropic glutamate 5 receptors in the acute tolerance to ethanol inhibition of spinal NMDA-induced pressor effects in rats. The 25th Joint Annual Conference of Biomedical Science 2010 :P102.

40. Lai C-C, Hsieh W-K. Role of metabotropic glutamate receptor 5 in ethanol regulation of NMDA receptor function and in ethanol-induced change in blood pressure in rats. Basic & Clinical Pharmacology & Toxicology 2010 ; 107 (Suppl. 1):399.

41. Wu T-Y, Lai C-C. Role of metabotropic glutamate receptor 5 in ethanol-induced changes in blood pressure in rats. The 25th Joint Annual Conference of Biomedical Science 2010 :P604.

42. Hsieh W-K, Lin H-H, Lai C-C. Changes in phosphorylation of NMDA receptor NR1 and NR2B subunits after acute ethanol treatment in rat sympathetic preganglionic neurons in vivo. The 26th Joint Annual Conference of Biomedical Science 2011 :P97.

43. Lai C-C, Keng N-T, Hsieh W-K. Ethanol regulation of the inhibitory effects of ketamine on spinal NMDA-induced pressor responses in rats. 8th IBRO World Congress of Neuroscience 2011 :A099.

44. Lin H-H, Wu Y-W, Kuo C-Y, Lo H, Lai C-C. Metabotropic glutamate receptor 5-mediated NMDA receptor activity in the RVLM contributes to methamphetamine-induced hypertension. The 7th Congress of the Federation of Asian and Oceanian Physiological Societies 2011 :S07-4.

45. Lo H, Sie M-J, Lai C-C. Inhibitory action of free fatty acid receptor 1 agonists on NMDA receptor function in rat sympathetic preganglionic neurons in vivo and in vitro. The 7th Congress of the Federation of Asian and Oceanian Physiological Societies 2011 :P-D08.

46. Lai C-C. Involvement of metabotropic glutamate receptor 5 in the regulation of ethanol-induced changes in blood pressure in rats. The Journal of Physiological Sciences 2012; 62 supplement 1:1PJ-187.

47. Lin Y-Z, Lai C-C. Ethanol regulation of the level of glutamate release in the rostral ventrolateral medulla in spontaneously hypertensive and normotensive rat. The 27th Joint Annual Conference of Biomedical Science 2012 :P849.

48. Wang H-Y, Lai C-C. Detection of spinal cord-derived vasorelaxing factor. The 27th Joint Annual Conference of Biomedical Science 2012 :P848.

49. Chen C-K, Lai C-C. The role of NMDA and GABA receptors in acute alcohol intoxication-related cardiovascular effects in conscious SD rats. The 28th Joint Annual Conference of Biomedical Science 2013 :P512.

50. Lin H-H, Chen J, Lai C-C. Chronic intermittent hypoxia induced changes in NMDA receptor subunits in central autonomic regions. Acta Pharmacologica Sinica 2013; 34 Supplement:S6.61.

51. Lo H, Zheng Z-T, Lin H-H, Lai C-C. Involvement of NMDA receptors in the rostral ventrolateral medulla in acute ethanol-induced depressor responses in spontaneously hypertensive rats. Acta Pharmacologica Sinica 2013; 34 Supplement:S6.64.

52. Cheng T-T, Lai C-C. Role of nitric oxide in alcohol-induced depressor effects in spontaneously hypertensive and normotensive rats. The 29th Joint Annual Conference of Biomedical Science 2014 :P554.

53. Lai C-C. Critical role of nitric oxide in central sympathetic nuclei in mediating acute alcohol-induced depressor responses. World Congress of Basic & Clinical Pharmacology 2014:Poster No. 49.

54. Lo H, Lin H-H, Lai C-C. Changes in Nitric-Oxide Signaling and GABA Neurotransmission in the Rostral Ventrolateral Medulla Contribute to Acute Ethanol-Induced Blood Pressure Response. The 31st Joint Annual Conference of Biomedical Science 2016 :P525.

55. Situmorang J, Lin H-H, Lai C-C. Increase in Heart Rate and Decrease in Nitric Oxide Synthase Expression in the Medulla after Subacute Administration of Ethanol. The 31st Joint Annual Conference of Biomedical Science 2016 :P548.

56. Situmorang JH, Lin H-H, Lai C-C. Protective effect of neuronal nitric oxide synthase (nNOS) in medulla oblongata on ethanol- induced tachycardia in female rats. The 32nd Joint Annual Conference of Biomedical Science 2017 :PH086.

57. Situmorang JH, Lin H-H, Lai C-C. Enhancement of ethanol-induced tachycardia following blockade of central estrogen α and β receptors in female rats The 34th Joint Annual Conference of Biomedical Science 2019 :PH102.

58. Lai C-C, Situmorang JH, Lin HH. Regulaiton by central estrogen receptors of ethanol-induced tachycardia in female rats. Chicago, IL: Society for Neuroscience 2019 :Program No. 769.01.

59. Lin H-H, Lai C-C, Fang C, Kuo C-Y, Wu Y-W. Activation of metabotropic glutamate receptor subtype 5 and protein kinase C pathways in the rostral ventrolateral medulla as a central mechanism for methamphetamine-induced pressor effect in rats. Chicago, IL: Society for Neuroscience 2019 :Program No. 770.12.

60. Lin, H.-H.; Lai, C.-C.; Islam, M. S., Attenuation of NMDA-induced pressor effects by intracerebroventricular amyloid-beta peptide 1-40 in the rostral ventrolateral medulla of rats. World Congress of Basic & Clinical Pharmacology 2023, Poster No. 158.

61. Lai, C.-C.; Lin, H.-H.; Situmorang, J. H.; Islam, M. S., Ovariectomy Exacerbates Acute Ethanol-Induced Tachycardia in female rats: Role of Nitric Oxide in the Rostral Ventrolateral Medulla. World Congress of Basic & Clinical Pharmacology 2023, Poster No. 156.