Those who use the TLVs MUST consult the latest Documentation to ensure that they understand the basis for the TLV and the information used in its development. The amount and quality of the information that is available for each chemical substance varies over time.

Chemical substances with equivalent TLVs (i.e., same numerical values) cannot be assumed to have similar toxicologic effects or similar biologic potency. In this book, there are columns listing the TLVs for each chemical substance (that is, airborne concentrations in parts per million [ppm] or milligrams per cubic meter [mg/m3]) and critical effects produced by the chemical substance. These critical effects form the basis of the TLV.


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Additional copies of the TLVs and BEIs book and the multi-volume Documentation of the Threshold Limit Values and Biological Exposure Indices, upon which this book is based, are available from ACGIH. Documentation of individual TLVs is also available. Consult the ACGIH website (acgih.org/store) for additional information and availability concerning these publications.

The Most Cited Journal in Analytical Chemistry*Analytical Chemistry is a peer-reviewed research journal that is devoted to the dissemination of new and original knowledge in all branches of analytical chemistry. Fundamental articles may address the general principles of chemical measurement science without directly studying existing analytical methodology as long as what is discussed relates to an important chemical parameter. Articles may be theoretical or they may report experimental results. They may contribute to any phase of analytical operations including sampling, measurements, and data analysis; the articles should target fields including, but not limited to, bioanalytical chemistry, bioengineering, chemical analysis, environmental sciences, forensics and medical sciences. Topics commonly include chemical reactions and selectivity, chemometrics and data processing, electrochemistry, elemental and molecular characterization, imaging, instrumentation, mass spectrometry, microscale and nanoscale systems, -omics, sensing, separations, spectroscopy, and surface analysis. Papers dealing with established analytical methods need to offer a significantly improved, original application of the method.

If a submission exceeds the length guidelines, it will be returned to the authors to be shortened or modified to fit another manuscript category. Although it may be appropriate that some experimental detail be included in the Supporting Information, it is not acceptable to place important details of the experiments there in order to circumvent the length guidelines.

While this document will provide basic information on how to prepare and submit the manuscript as well as other critical information about publishing, we also encourage authors to visit the ACS Publishing Center for additional information on everything that is needed to prepare (and review) manuscripts for ACS journals and partner journals, such as

All ACS journals and partner journals have simplified their formatting requirements in favor of a streamlined and standardized format for an initial manuscript submission. Read more about the requirements and the benefits these serves authors and reviewers here.

See the list of Acceptable Software and appropriate File Designations to be sure your file types are compatible with ACS Paragon Plus. Information for manuscripts generated from TeX/LaTeX is also available.

Title. Use specific and informative titles with a high keyword content. Avoid acronyms and subtitles. Either the title or the abstract must contain the name(s) of the central measurement methodology (or methodologies) used in the paper.

Text. Consult the publication for the general writing style. Write for the specialist (except for Tutorials, which should be written for the scientific generalist). It is not necessary to include information and details or techniques that should be common knowledge to those in the field.

Experimental Section. Use complete sentences (i.e., do not use outline form). Be consistent in voice and tense. For apparatus, list only devices of a specialized nature. List and describe preparation of special reagents only. Do not list those normally found in the laboratory and preparations described in standard handbooks and texts. Because procedures are intended as instructions to permit work to be repeated by others, give adequate details of critical steps. While it is acceptable to report some of the detailed procedures as supporting information, important and unique experimental procedures must remain in the main manuscript.

Published procedures should be cited but not described, except where the presentation involves substantial modifications. While an experimental section is required to be in the main article and should provide sufficient detail to understand the experiments, detailed procedures may be presented in the Supporting Information.

Acknowledgments. Authors may acknowledge technical assistance, gifts, the source of special materials, financial support, meeting presentation information, and the auspices under which work was done, including permission to publish. During manuscript submission, the submitting author is asked to select funding sources from the list of agencies included in the FundRef Registry.

This information is provided to the reviewers during the peer-review process (for Review Only) and is available to readers of the published work (for Publication). Supporting Information must be submitted at the same time as the manuscript. See the list of Acceptable Software by File Designation and confirm that your Supporting Information is viewable.

If the manuscript is accompanied by any supporting information files for publication, these files will be made available free of charge to readers. A brief, nonsentence description of the actual contents of each file, including the file type extension, is required. This description should be labeled Supporting Information and should appear before the Acknowledgement and Reference sections. Examples of sufficient and insufficient descriptions are as follows:

Research data is defined as materials and information used in the experiments that enable the validation of the conclusions drawn in the article, including primary data produced by the authors for the study being reported, secondary data reused or analyzed by the authors for the study, and any other materials necessary to reproduce or replicate the results.

The quality of illustrations in ACS journals and partner journals depends on the quality of the original files provided by the authors. Figures are not modified or enhanced by journal production staff. All graphics must be prepared and submitted in digital format.

Manuscripts, graphics, supporting information, and required forms, as well as manuscript revisions, must all be submitted in digital format through ACS Paragon Plus, which requires an ACS ID to log in. Registering for an ACS ID is fast, free, and does not require an ACS membership. Please refer to Appendix 1 for additional information on preparing your submission

Analytical Chemistry considers for publication original work that has not been previously published and is not under consideration for publication elsewhere. Related work under consideration for publication in any medium must be cited in the manuscript and the Editor informed at the time of submission. In addition, an author must inform the Editor of prior dissemination of the content in print or electronic formats in the cover letter. Analytical Chemistry authors are allowed to deposit an initial draft of their manuscript on a recognized preprint server such as ChemRxiv, bioRxiv, arXiv, or the applicable repository for their discipline prior to submission. Please note any use of a preprint server in the cover letter and include a link to the preprint, and as appropriate, state how the manuscript has been adjusted/updated between deposition and submission. Upon publication in Analytical Chemistry, authors are advised to add a link from the preprint to the published paper via the Digital Object Identifier (DOI). ChemRxiv and bioRxiv add this link for authors automatically after publication.

A Manuscript PDF File is optional. If uploaded, this file will be used as the PDF proof during the peer review process. Authors must view and approve the PDF version of their manuscript prior to formal submission to the Editor.

In cases when reviewers make different or conflicting recommendations, the Editors may request additional information from the reviewers, consult other experts, and/or ask the authors to clarify sections in question. Some manuscripts that are declined may be considered upon resubmission if significant additional work is completed, but authors are required to let the Editor know that the work is being resubmitted for reconsideration.

The Editors strongly disapprove of any attempts by authors to determine the identity of reviewers or to confront potential reviewers. The editorial policy of this journal is neither to confirm nor to deny any speculation about the identities of our reviewers. Authors whose manuscripts are published in Analytical Chemistry are expected to review manuscripts submitted by other researchers from time to time. Information for Reviewers is published separately.

Publication of manuscripts on the Web may occur weeks in advance of the cover date of the issue of publication. Authors should take this into account when planning their patent and intellectual property activities related to a document and should ensure that all patent information is available at the time of first publication, whether ASAP or issue publication.

All articles published ahead of print receive a unique Digital Object Identifier (DOI) number, which is used to cite the manuscript before and after the paper appears in an issue. Additionally, any supplemental information submitted along with the manuscript will automatically be assigned a DOI and hosted on Figshare to promote open data discoverability and use of your research outputs. ff782bc1db

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