In-scope: scale ups of existing projects where the prize represents most of the overall needed budget; innovative green & sustainable chemistry solutions implemented in the Global South. For example, projects looking at Sustainable Chemistry Solutions: Waste Utilization; Alternative Energy Sources; Biodiversity and Ecosystem Health; Climate Change Mitigation; Community Empowerment; Sustainable Agriculture; Water Resource Management; Health and Well-being:

Out-of-scope: projects to be implemented outside of low-and-middle income countries; projects with no gender component, educational projects without a strong scientific green & sustainable chemistry component; prize money mainly used on expensive equipment; prize money mainly used on personnel; projects in the Global South without a local implementation partner.


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The Medicinal and Bioorganic Chemistry Foundation was incorporated in 1994 as a 501(c )(3) federally tax-exempt non-profit organization and was established for the arrangement and sponsorship of international conferences, symposia, and educational programs which are dedicated to the advancement of bioorganic, synthetic organic and medicinal chemistry.

The signature You Be The Chemist programs uniquely connect business and education in local communities, to reach students early in life and ignite a passion for chemistry and science-related careers.

The Herman Frasch Fund for Chemical Research is a trust created under the will of Elizabeth Blee Frasch, administered by Bank of America, N.A. as Trustee. The American Chemical Society advises the Trustee on the Frasch program. The purpose of the Foundation is to award grants to nonprofit incorporated institutions to support research in the field of agricultural chemistry which will be of practical benefit to the agricultural development of the United States.

ACS GCI Pharmaceutical Roundtable Research Grant Addressing key synthetic chemistry and process research challenges whose solutions result in more efficient pharmaceutical process development and production.

Early Career Postdoctoral-Faculty Bridge Grant The ACS Campaign for a Sustainable Future aims to advance chemistry innovations to address the challenges articulated in the U.N. Sustainable Development Goals.

During disease epidemics, flooding, or other natural disasters, supplying chlorine based materials enhances access to safe drinking water and enables people to disinfect surfaces to reduce the spread of infectious diseases. The CCF continues a long standing partnership between the chlorine chemistry industry and disaster relief organizations, such as World Vision, to help impacted communities recover from natural disasters and epidemics.

Enabling the exchange of knowledge is a powerful tool to enhance responses to epidemics, improve the safety of workers, and discover innovative applications of chlorine chemistry that benefit society. The CCF promotes the exchange of knowledge by supporting organizations that disseminate information that enhances public health and safety.

All it takes is a spark. The mission of the Kaufman Foundation is to support fundamental research in biology, chemistry, and physics at Pennsylvania institutions of higher education. The Foundation distributes grants in two areas: New Investigator Research and New Initiative Research.

To keep the scope of this treatment manageable but while meeting the book's prime purpose to provide a foundation to the topic of chemistry for sustainable development, there will be some matters that are not explored in the detail to satisfy every reader. In these instances, I point to accessible and peer-reviewed sources of additional information which readers could profitably explore further.

The selection of topics addressed and the examples used to illustrate them are governed, to a large extent, by the fact that this book is aimed primarily at chemists and chemical technologists. The selection I have made is different from that which those with other specialisms and interests might have made. That this is so is a reflection of the complexity and inter-relatedness of sustainable development and sustainability (Glaze called this 'hyperdisciplinarity'), something that it is important, at the outset, to recognise. The role of chemistry, and of science itself, is shown to be critically important. While absolutely necessary, however, neither is sufficient.

The theme running through the book is chemistry's central importance both to our attempts to understand the environment and the lifeforms that populate it, as well as to our efforts to develop ways to make the demands of the human population on the planet's resources (and its associated impact) more sustainable. The technological application of chemistry requires some basic understanding of process engineering and process economics and these are introduced as part of the foundation that represents the purpose of this book. Furthermore, this foundation also encompasses the economic and social context (and associated political ramifications) of technological development, particularly relating to the challenge of climate change.

Whatever position one takes on the role of technology, it is inescapable that the physical and chemical processes taking place in the environment are governed by the same laws that control all of chemistry. Understanding the environmental chemistry perspective, therefore, is important in addressing questions of sustainable development. I introduce environmental chemistry and the associated topic of climate change in Chapter 5.

This unit has been designed to combine scientific content, theoretical principles and associated laboratory skills. The unit develops the concepts in physical, inorganic and organic chemistry that are required for studying chemistry at higher levels and interdisciplinary science. The unit begins with the consideration of atomic structure and chemical bonding and enables the student to carry out chemical calculations involving the mole and progresses to more complex scientific principles such as thermodynamics, kinetics and equilibrium.

BIOVECTRA traces its origins back to 1970 when Regis Duffy, the Dean of Science at the University of Prince Edward Island, founded Diagnostic Chemicals Ltd. (DCL) in a makeshift lab to create summer job opportunities for students. DCL initially produced small molecules for diagnostic reagents and later expanded to offer contract development and manufacturing services for diagnostics and pharmaceuticals in 2000. In 2001, the bioscience division BioVectra DCL was established, focusing on microbial fermentation to produce small molecule active pharmaceutical ingredients (APIs). PEGylation chemistry expertise was developed, and fermentation capabilities expanded to include biologics production. The diagnostics division was sold to Genzyme in 2007, and the company renamed itself BioVectra Inc. In 2019, H.I.G. Capital acquired BioVectra, continuing investments and expansions.

In essence, chemistry has always been the central anchor for BIOVECTRA and has enabled the company to expand into multiple spheres of activity, allowing it to continually build and grow throughout its history. As a result, BIOVECTRA has offered a unique combination of synthetic organic chemistry, fermentation of chemical and biologic molecules (including highly potent compounds), downstream processing, methoxy polyethylene glycol derivatives (mPEG) production, and conjugation chemistry services for more than four decades to small and large pharmaceutical, biotechnology, generic, and early-stage drug development companies.

In total, BIOVECTRA has submitted over 15 product filings, including Abbreviated New Drug Applications (ANDAs), Drug Master Files (DMFs), Veterinary Master Files (VMFs), and chemistry, manufacturing, and controls (CMC) section preparations for both the U.S. Food and Drug Administration and Health Canada. We support customers with challenging molecules, including cytotoxic active ingredients and APIs that must be semisynthesized from metabolites via highly challenging fermentations. Through strategic partnerships, the company has developed several generic products, including highly potent particulate injectable formulations and controlled-release drugs. BIOVECTRA also offers current Good Manufacturing Practice (cGMP) bioprocessing reagents, such as dithiothreitol (DTT) and tris-(2-carboxyethyl)phosphine hydrochloride (TCEP-HCI), and develops custom solutions for mPEG functionalization using proprietary, scalable chemistries.

The ability to synthesize complex small molecule APIs using synthetic organic chemistry and/or fermentation processes provides tremendous advantages for BIOVECTRA's clients. Many small and emerging biopharma companies at early stages of development have not yet established optimized manufacturing processes. The ability to explore both traditional chemistry and fermentation routes provides them the opportunity to truly identify the most cost-effective approach for obtaining the highest-quality material.

This combined expertise in fermentation and synthetic chemistry is unique in the contract manufacturing sector. Moreover, its benefits are not limited to clients requiring production of complex cytotoxic compounds. Customers also come to BIOVECTRA for manufacturing of bioconjugates, as we can provide end-to-end support, including fermentation of proteins, synthesis of mPEGs, and the chemistry enabling bioconjugation. As an example, one customer that used to rely on four separate service providers (one for each protein, one for mPEG synthesis, and one for bioconjugation) had its entire bioconjugate molecule manufactured at BIOVECTRA, dramatically simplifying the supply chain and thus reducing the time and cost required to produce the product.

The overall goal for any CDMO should be to develop the most efficient, optimized route for each client molecule. With its ability to offer synthetic chemistry methods that include both chemo- and biocatalytic reactions, as well as fermentation, BIOVECTRA offers more opportunities for achieving that goal. The company has also developed expertise in flow chemistry, a manufacturing approach that reduces resource consumption and by-product, waste, and emissions production, leading to more cost-effective production of higher-quality products. e24fc04721

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