基本資料
姓名:
黃盈誠
電子信箱:
連絡電話/傳真:
0975365509 / 03-3285818
服務機構 / 服務單位 / 現任職稱 (可多項填寫):
Associate Professor, Division of Neurosurgery, Chang Gung Memorial Hospital
機構地址:
333 桃園市龜山區復興街5號
個人網站:
研究領域:
Stem cell and gene therapy, Neuro-oncology, immuno-oncology
個人簡歷
After graduation from Kaohsiung Medical University, I have completed my neurosurgical resident training in Chang Gung Memorial Hospital, Linkou. Then I obtained my Ph.D. degree from Institute of Clinical Biomedical science, Chang Gung University. The main research field is neuroscience, especially neuro-biology and neuro-oncology.
發表論文或著作等
1. Lee CC, You JF, Wang YC, Lan SW, Wei KC, Chen KT, Huang YC, Wu TE, Huang AP (2022, Aug). Gross Total Resection Promotes Subsequent Recovery and Further Enhancement of Impaired Natural Killer Cell Activity in Glioblastoma Patients. Brain sciences, 12(9):1144. (SCIE).
2. Zheng YC, Liu YT, Wei KC, Huang YC, Chen PY, Hsu YH, Lin CL (2022, Jul). Outcome predictors and clinical presentation of syringomyelia. Asian Journal of Surgery, S1015-9584(22)00891-0. (SCIE).
3. Yeap MC, Chen CC, Chen CT, Liu ZH, Wu CT, Hsieh PC, Lai HY, Wang YC, Chang TW, Lee CC, Liu YT, Huang YC, Wei KC, Tu PH (2022, Jun). Predictive Value of Swab Cultures for Cryopreserved Flaps During Delayed Cranioplasties. World Neurosurgery, 157:e173-e178. (SCIE).
4. Huang YC, Liu ZH, Kuo CY, Chen JP (2022, May). Photo-Crosslinked Hyaluronic Acid/Carboxymethyl Cellulose Composite Hydrogel as a Dural Substitute to Prevent Post-Surgical Adhesion. International Journal of Molecular Sciences, 23(11):6177.. (SCI).
5. Lin SY, Chuang CC, Tsan DL, Hung YS, Fu CJ, Shen YL, Chiang YY, Huang YC, Lu YJ, Yang CC (2022, May). Maintenance of multi-domain neurocognitive functions in patients with newly-diagnosed primary CNS lymphoma after primary cranial radiotherapy combined with methotrexate-based chemotherapy: A preliminary case-series study. Applied neuropsychology. Adult, 29(3):432-441.
6. Tu PH, Liu ZH, Yeap MC, Liu YT, Li YC, Huang YC, Lin TM, Chen CC (2022, May). Spinal cord injury and spinal fracture in patients with ankylosing spondylitis. BMC emergency medicine, 22(1):73. (SCIE).
7. Lin YJ, Huang CY, Shen YC, Wei KC, Chuang CC, Hsu PW, Huang YC, Hwang TL, Chen PY (2022, Apr). A manzamine-derived compound as a potential therapeutic agent for glioma by inducing apoptosis and cell cycle arrest. American journal of cancer research, 12(4):1740-1751. (SCIE).
8. Lin SY, Chuang CC, Huang YC, Pai PC, Lee CC, Wei KC, Tseng CK, Yang CC. (2022, Mar). Neuropsychological performances in patients with infiltrative non-GBM gliomas after postoperative adjuvant photon or proton radiotherapy: A prospective and preliminary investigation. Applied neuropsychology. Adult, 27:1-10.
9. Liu ZH, Huang YC, Kuo CY, Chuang CC, Chen CC, Chen NY, Yip PK, Chen JP. (2022, Jan). Co-Delivery of Docosahexaenoic Acid and Brain-Derived Neurotropic Factor from Electrospun Aligned Core-Shell Fibrous Membranes in Treatment of Spinal Cord Injury. Pharmaceutics, 14(2):321.
10. Li YC, Chiu HY, Wei KC, Lin YJ, Chen KT, Hsu PW, Huang YC, Chen PY (2021, Dec). Using cortical function mapping by awake craniotomy dealing with the patient with recurrent glioma in the eloquent cortex. Biomedical journal, 44(6 Suppl 1):S48-S53. (SCIE).
11. Lin SJ, Huang YC, Chen HY, Fang JY, Hsu SY, Shih HY, Liu YC, Cheng YC. (2021, Dec). RGS2 Suppresses Melanoma Growth via Inhibiting MAPK and AKT Signaling Pathways. ANTICANCER RESEARCH, 41(12):6135-6145. (SCIE).
12. Yeh, TH, Liu HF, Chiu CC, Cheng ML, Huang GJ, Huang YC, Liu YC, Huang YZ, Lu CS, Chen YC, Cheng HY, Cheng YC (2021, Dec). PLA2G6 mutations cause motor dysfunction phenotypes of young-onset dystonia-parkinsonism type 14 and can be relieved by DHA treatment in animal models. EXPERIMENTAL NEUROLOGY.
13. HUANG YC, LAI JCY, PENG PH, WEI KC, WU KJ (2021, Nov). Chromatin accessibility analysis identifies GSTM1 as a prognostic marker in human glioblastoma patients. CLINICAL EPIGENETICS, (2021) 13:201.
14. Su ML, Liu ZH, Tu PH and Huang YC (2021, Nov). Dynamic cervical flexion/extension atlantodental interval and functional outcome of the Harms technique for posterior C1/2 fixation: A retrospective analysis of 16 atlantoaxial subluxation cases in a tertiary medical center. Neurochirurgie .
15. Lee CC, Wang YC, Liu YT, Huang YC, Hsu PW, Wei KC, Chen KT, Lin YJ, Chuang CC (2021, Apr). Incidence and Factors Associated with Postoperative Delayed Hyponatremia after Transsphenoidal Pituitary Surgery: A Meta-Analysis and Systematic Review. International Journal of Endocrinology, 10;2021:6659152. (SCIE).
16. Chen VC, Chou YS, Tsai YH, Huang YC, McIntyre RS, Weng JC (2021, Mar). Resting-State Functional Connectivity and Brain Network Abnormalities in Depressive Patients with Suicidal Ideation. BRAIN TOPOGRAPHY, 34(2):234-244. (SCIE).
17. Li YC, Chiu HY, Lin YJ, Chen KT, Hsu PW, Huang YC, Chen PY, Wei KC (2021, Jan). The Merits of Awake Craniotomy for Glioblastoma in the Left Hemispheric Eloquent Area: One Institution Experience. CLINICAL NEUROLOGY AND NEUROSURGERY, 200:106343. (SCIE).
18. Liu YT, Chen GT, Huang YC, Ho JT, Lee CC, Tsai CC, Chang CN (2020, Dec). Effectiveness of dose-escalated topiramate monotherapy and add-on therapy in neurosurgery-related epilepsy: A prospective study. Medicine (Baltimore), 99(52):e23771. (SCIE).
19. Liu ZH, Huang YC, Kuo CY, Kuo CY, Chin CY, Yip PK, Chen JP (2020, Sep). Docosahexaenoic Acid-Loaded Polylactic Acid Core-Shell Nanofiber Membranes for Regenerative Medicine after Spinal Cord Injury: In Vitro and In Vivo Study. Int J Mol Sci , 020 Sep 24;21(19):7031.
20. Chio CM, Huang YC, Chou YC, Hsu FC, Lai YB, Yu CS. (2020, Mar). Boron accumulation in brain tumor cells through Boc-protected tryptophan as a carrier for boron neutron capture therapy. Medicinal Chemistry Letter, 11, 4, 589–596.
21. Yeap MC, Tu PH, Liu ZH, Hsieh PC, Liu YT, Lee CY, Lai HY, Chen CT, Huang YC, Wei KC, Wu CT, Chen CC (2019, Aug). Long-Term Complications of Cranioplasty Using Stored Autologous Bone Graft, Three-Dimensional Polymethyl Methacrylate, or Titanium Mesh After Decompressive Craniectomy: A Single-Center Experience After 596 Procedures. World Neurosurgery, 128:e841-e850.
22. Chen CH, Chen PY, Lin YY, Feng LY, Chen SH, Chen CY, Huang YC, Huang CY, Jung SM, Chen LY, Wei DK (2019, Jan). Suppression of tumor growth via IGFBP3 depletion as a potential treatment in glioma. Neurosurgery, 11;132(1):168-179.
23. Hsieh YC, Chiang MC, Huang YC, Yeh TH, Shih HY, Liu HF, Chen HY, Wang CP, Cheng YC. (2018, Dec). Pparα deficiency inhibits the proliferation of neuronal and glial precursors in the zebrafish central nervous syste. DEVELOPMENTAL DYNAMICS, 247(12):1264-1275.
24. Chen VC, Yang YH, Kuo TY, Huang KY, Huang YC, Lee Y, McIntyre RS, Huang YS, Hsu CY (2018, Sep). Increased Incidence of Obstructive Sleep Apnea in Hospitalized Children After Enterovirus Infection: A Nationwide Population-based Cohort Study. The Pediatric infectious disease journal, 37(9):872-879.
25. Yeap MC, Chen CC, Liu ZH, Hsieh PC, Lee CC, Liu YT, Yi-Chou Wang A, Huang YC, Wei KC, Wu CT, Tu PH (2018, Sep). Postcranioplasty seizures following decompressive craniectomy and seizure prophylaxis: a retrospective analysis at a single institution. Journal of neurosurgery, 131(3):936-940.
26. Ching CC, Lu CS, Weng YH, Chen YL, Huang YZ, Chen RS, Cheng YC, Huang YC, Liu YC, Lai SC, Lin KJ, Lin YW, Chen YJ, Chen CL, Yeh TH, Wan HL. (2018, Aug). PARK14 (D331Y) PLA2G6 Causes Early-Onset Degeneration of Substantia Nigra Dopaminergic Neurons by Inducing Mitochondrial Dysfunction, ER Stress, Mitophagy Impairment and Transcriptional Dysregulation in a Knockin Mouse Model. . Mol Neurobiol. .
27. Chang CW, Yeh CN, Chung YH, Chen YR, Tien SW, Chen TW, Farn SS, Huang YC, Yu CS. (2018, May). Synthesis and evaluation of ortho-[18F] fluorocelecoxib for COX-2 cholangiocarcinoma imaging. . Drug Des Devel Ther, 24;12:1467-1478.
28. LinYJ, Chen KT, Lee CC, Toh CH, Wu CE, Huang YC, Lu YJ, Chuang CC, Chen PY, Wei KC (2018, Mar). Anterior Skull Base Tumor Resection by Transciliary Supraorbital Keyhole Craniotomy: A Single Institutional Experience. . World Neurosurg..
29. Yeh TH, Liu HF, Li YW, Lu CS, Shih HY, Chiu CC, Lin SJ, Huang YC, Cheng YC. (2018, Mar). C9orf72 is essential for neurodevelopment and motility mediated by Cyclin G1 . Exp Neurol , 6;304: 114-124.
30. Chen CC, Chen SW, Tu PH, Huang YC, Liu ZH, Yi-Chou Wang A, Lee ST, Chen TH, Cheng CT, Wang SY, Chou AH (2018, Feb). Outcomes of chronic subdural hematoma in patients with liver cirrhosis. . J Neurosurg.
31. Chen PC, Huang YC, Chang CN, Chen JL, Hsu CC, Lin WY. (2018, Feb). Changes of cerebrospinal fluid protein concentrations and gait patterns in geriatric normal pressure hydrocephalus patients after ventriculoperitoneal shunting surgery. . Exp. Gerontol., 106:109-115.
32. Huang YC, Farn SS, Chou YC, Yeh CN, Chang CW, Chung YHm Chen TW, Huang WS, Yu CS. (2018, Jan). Synthesis of para-[18F]Fluorofenbufen Octylamide for PET Imaging of Brain Tumors. . J of the Chinese Chemical Society.
專利
Construction and screening of solution-phase derived library of fenbufen and ethacrynic acid, 美國, National Tsing Hua University, Taiwan, Yu Chung-Shan; Su, Yuan-Hsiao; Chiang, Li-Wu; Chen, Chia-Rong; Chen, Shao-Wei; Huang, Chia-Wen; Huang, Ho-Lien; Huang, Yin-Cheng, US 8,093,427 B2, 2012年1月10日
治療癌症的芬布芬衍生物, 台灣, 國立清華大學, 俞鐘山,黃盈誠,黃鶴聯,蘇元孝,林珈融,黃佳雯,陳劭緯,薛敬和,姜豊武, 中華民國專利第I450715號, 2013年1月7日
Method of preparing [123I]iodooctyl fenbufen amide and application thereof, 美國 (Approval of the patent, formal document will be received by 2015, May), National Tsing Hua University, Taiwan, Yu, Chung-Shan; Huang, Ho-Lien; Yeh, Chun-Nan; Lee, Wei-Yuan; Chang, Kang-Wei; Huang, Ying-Cheng; Lin, Kun-Ju; Yang, Ching-Shiuann; Tien, Shu-Fan; Su, Wen-Chin; Chen, Jenn-Tzong; Lin, Wuu-Jyh; Farn, Shiou-Shiow, US 20140079633 A1, 2014年5月20日
Method of preparing ethacrynic amide derivatives useful for positron emission tomog. of a tumor liver or a liver disease, 美國, National Tsing Hua University, Taiwan, Yu, Chung Shan; Yeh, Chun Nan; Chen, Jenn-Tzong; Lin, Wuu-Jyh; Huang, Yin-Cheng; Chiang, Li-Wu; Huang, Hao Lien; Chang, Kang-Wei; Chen, Gon-Shen; Lin, Ken-Hong; Wang, Wei-Ting, US 20130156701 A1, 2013年6月20日
完整個人履歷(學歷、經歷、殊榮、學會或專業認證…等)
Education:
PhD
Sep, 2003~ Jun, 2009
Graduate Institute of Clinical Medical Sciences
Chang Gung University
M.D.
July 1986 ~ June 1993, School of Medicine, Medical College,
Kaoshiung Medical University, Kaoshiung, Taiwan
Resident
June, 1995~ June 1996, Department of Surgery,
Taipei Veterans Hospital
July, 1996~ July, 1997, Department of Surgery,
Chang Gung Memorial Hospital, Linkou
July, 1997~ July, 2001, Department of Neurosurgery,
Chang Gung Memorial Hospital, Linkou
Fellow
Aug, 2000~ Oct, 2000, Department of Neuropahtology,
Western Hospital, Toronto, Canada.
Post-doc
Oct, 2005~ Sep, 2007, Department of Neurosurgery,
Institute of Regeneration Medicine, UCSF, USA
Employment:
July, 2015~Associate professor, department of neurosurgery
Jul, 2011~Assistant professor, department of neurosurgery
Sep, 2001 ~Attending staff, Department of Neurosurgery
Chang Gung Memorial Hospital
4. Jul, 1996~Aug, 2001
Resident, Department of Neurosurgery
Chang Gung Memorial Hospital
5. Jul, 1995~Jul, 1996
Resident, Department of Surgery
Veteran General Hospital, Taipei