黃瓊瑩
基本資料
姓名：
黃瓊瑩
電子信箱：
連絡電話/傳真：
TEL: 03-3281200 ext 7910
服務機構 / 服務單位 / 現任職稱 (可多項填寫)：
長庚醫院/神經外科/博士後研究員
機構地址：
桃園市龜山區復興路五號
個人網站：
研究領域：
分子生物學、神經腫瘤學、奈米醫學、腦部藥物傳遞、生物實驗技術
個人簡歷
主要學歷
高雄醫學大學 藥學系 學士 1988/9至1991/6
高雄醫學大學 基礎醫學研究所藥理學組 碩士 1992/9至1994/6
國立陽明大學 熱帶醫學研究所 博士 1997/9至2005/6
現職及與專長相關之經歷
2006/01 -present 長庚紀念醫院神經外科，博士後研究員
2005/12 浙江大學沃森基因組科學研究院 基因組科學生物訊息研習班
2004/01-2004/05 Department of Animal Health and Biomedical Sciences, School of Veterinary Medicine, University of Wisconsin Madison, Wisconsin, U.S.A.訪問學者
2003/01-2003/02 Department of Genetics, Case Western Reserve University, Ohio, U.S.A.訪問學者
1995/09-1998/08 長庚大學醫學系，專任教學助教
1992/08-1993/08 高雄醫學大學附設中和紀念醫院內分泌科，研究助理
發表論文或著作等
1. Tamang D, Tseng SM, Huang CY, Tsao IY, Chou SZ, Higgs S, Christensen BM, Chen CC. The use of a double subgenomic Sindbis virus expression system to study mosquito gene function: effect of antisense nucleotide number and duration of viral infection on gene silencing efficiency. Insect Molecular Biology. 2004, 13:595-602(SCI; IF2021=3.424; Entomology 16/100)
2. Bartholomay LC, Cho WL, Rocheleau TA, Boyle JP, Beck ET, Fuchs JF, Liss P, Rusch M, Bulter KM, Wu RCC, Lin SP, Kou HY, Tsao IY, Huang CY, Wu TT, Hisao KJ, Tsai SF, Yang UC, Nappi AJ, Perna NT, Chen CC, Christensen BM. Transcriptome analysis of immune-activated hemocytes from Aedes aegypti and Armigeres subalbatus mosquitoes. Infection and Immunity 2004, 72: 4114-4126 (SCI; IF2021=3.616; Infectious disease 62/95)
3. Huang CY, Chou SY, Bartholomay LC, Christensen BM, Chen CC. The use of gene silencing to study the role of dopa decarboxylase in mosquito melanization reactions. Insect Molecular Biology. 2005, 14:237-244 (SCI; IF2021=3.424; Entomology 16/100) (first author)
4. Huang CY, Christensen BM, Chen CC. 2005 Role of dopachrome conversion enzyme in the melanization of filarial worms in mosquitoes. Insect Molecular Biology. 14:675-682 (SCI; IF2021=3.424; Entomology 16/100) (first author)
5. Mayhew GF, Bartholomay LC, Kuo HY, Rocheleau TA, Fuchs JF, Aliota MT, Tsao IY, Huang CY, Liu TT, Hsiao KJ, Tsai SF, Yang UC, Perna NT, Cho WL, Christensen BM, Chen CC. Construction and characterization of an expressed sequenced tag library for the mosquito vector Armigeres subalbatus. BMC Genomics. 2007, 8:4621.( SCI; IF2021=4.558; Genetics & heredity 50/175)
6. Huang BR, Chen PY, Huang CY, Chen JP, Jung SM, Ma YH, Wu T, Wei KC. The Bioavailability of magnetic nanoparticles to the brain. Journal of Magnetism and Magnetic Materials. 2009, 321: 1604–1609 (SCI, EI; IF2021=3.097; Physics, condensed matter 35/69)
7. Wei KC, Huang CY, Chen PY, Feng LY, Wu TE, Tsang NM, Tseng CK, Pai PC Shin JW. Evaluation of CD44 as biomarkers for brain tumor prognosis. Anticancer Research. 2010, Jan;30(1):253-9. (SCI; IF2021=2.435; Oncology 231/318)
8. Liu HL, Hua MY, Chen PY, Chu PC, Pan CH, Yang HW, Huang CY, Wang JJ, Yen TC, Wei KC. Blood–Brain Barrier Disruption by Focused Ultrasound Enhances Delivery of Chemotherapeutic Drugs for Glioblastoma Treatment. Radiology. 2010; 255:415-425. (SCI; IF2021=29.146; Radiology, nuclear medicine & medical imaging 1/136)
9. Chen PY, Liu HL, Hua MY, Yang HW, Huang CY, Chu PC, Pan CH, Hsu PH, Tseng IC, Wang JJ, Yen TC, Ma YH, Wu T, Chen JP, Chuang JI, Shin JW, Wei KC. Novel magnetic/ultrasound focusing system enhances nanoparticle drug delivery for glioma treatment. Neuro-oncology 2010 12:1050-1060 (SCI; IF2019=13.029; Clinical neurology 10/267)
10. Liu HL, Hua MY, Yang HW, Huang CY, Chu PC, Wu JS, Tseng IC, Wang JJ, Yen TC, Chen PY, Wei KC. Magnetic resonance monitoring of focused ultrasound/magnetic nanoparticle targeting delivery of therapeutic agents to the brain. Proc Natl Acad Sci U S A. 2010; 107:15205-15210 (SCI; IF2021= 12.779; Multidisciplinary sciences 8/71)
11. Hua MY, Liu HL, Yang HW, Chen PY, Tsai RY, Huang CY, Tseng IC, Lyu LA, Ma CC, Tang HJ, Yen TC, Wei KC. The effectiveness of a magnetic -nanoparticle-based delivery system for BCNU in the treatment of gliomas. Biomaterials 32(2):516-527, 2011(SCI; IF2021=15.304; Materials science, biomaterials 4/98)
12. Yang HW, Hua MY, Liu HL, Huang CY, Tsai RY, Lu YJ, Chen JY, Tang HJ, Hsien HY, Chang YS, Yen TC, Chen PY, Wei KC. Self-protecting core-shell magnetic nanoparticles for targeted, traceable, long half-life delivery of BCNU to gliomas. Biomaterials 32(27): 6523 -6532, 2011(SCI; IF2021=15.304; Materials science, biomaterials 4/98)
13. Liu HL, Chen PY, Yang HW, Wu JS, Tseng, IC, Ma, YJ, Huang CY, Tsai HC, Chen SM, Lu YJ, Huang, C.Y., Hua, M.Y., Ma, Y.H., Yen, T.C. and Wei KC. In vivo MR quantification of superparamagnetic iron oxide nanoparticle leakage during low-frequency-ultrasound-induced blood-brain barrier opening in swine. Journal of Magnetic Resonance Imaging. 34(6): 1313-1324, 2011. (SCI; IF2021=5.119; Radiology, nuclear medicine & medical imaging 34/136)
14. Ting CY, Fan CH, Liu HL, Huang CY, Hsieh HY, Yen TC, Wei KC, Yeh CK Concurrent blood-brain barrier opening and local drug delivery using drug-carrying microbubbles and focused ultrasound for brain glioma treatment. Biomaterials. 33(2): 704-712, 2012. (SCI; IF2021=15.304; Materials science, biomaterials 4/98)
15. Chen L, Wei KC, Huang ACH, Wang K, Huang CY, Yi D, Tang CY, Galas D Hood L. RNASEQR - A streamlined and accurate RNA-seq sequence analysis program. Nucleic acids research 2011, I-12 (SCI; IF2021=19.160; Biochemistry & molecular biology 8/297 )
16. Lu YJ, Yang HW, Hung SC, Huang CY, Li SM, Ma CC, Chen PY, Tsai HC, Wei KC, Chen JP. Improving thermal stability and efficacy of BCNU in treating glioma cells using PAA-functionalized graphene oxide. International Journal of Nanomedicine. 2012 Mar; 7: 1737-1747. (SCI; IF2021=7.033; Pharmacology & pharmacy 32/279)
17. Chen YC, Liao LC, Lu PL, Lo CL, Tsai HC, Huang CY, Wei KC, Yen TC, Hsiue GH. The accumulation of dual pH and temperature responsive micelles in tumors. Biomaterials. 2012 Jun; 33(18): 4576-4588. (SCI; IF2021=15.304; Materials science, biomaterials 4/98)
18. Wei KC, Tsai HC, Lu YJ, Yang HW, Hua MY, Wu MF, Chen PY, Huang CY, Yen TC, Liu HL. Neuronavigation-guided focused ultrasound-induced blood-brain barrier opening: a preliminary study in swine. American Journal of Neuroradiology. 2013 Jan; 34(1): 115-120. (SCI; IF2021=4.966; Radiology, nuclear medicine & medical imaging 36/136)
19. Hsu PH, Wei KC, Huang CY, Wen CJ, Yen TC, Liu CL, Lin YT, Chen JC, Shen CR, Liu HL. Noninvasive and targeted gene delivery into the brain using microbubble-facilitated focused ultrasound. PLoS One. 2013 Feb; 8(2): e57682. (SCI; IF2021=3.752; Multidisciplinary sciences 29/74)
20. Fan CH, Ting CY, Liu HL, Huang CY, Hsieh HY, Yen TC, Wei KC, Yeh CK. Antiangiogenic- targeting drug-loaded microbubbles combined with focused ultrasound for glioma treatment. Biomaterials. 2013 Mar; 34(8): 2142-2255. SCI; IF2021=15.304; Materials science, biomaterials 4/98)
21. Wei KC, Chu PC, Wang HY, Huang CY, Chen PY, Tsai HC, Lu YJ, Lee PY, Tseng IC, Feng LY, Hsu PW, Yen TC, Liu HL. Focused ultrasound-induced blood-brain barrier opening to enhance temozolomide delivery for glioblastoma treatment: a preclinical study. PLoS One. 2013 Mar; 8(3): e58995. (SCI; IF2021=3.752; Multidisciplinary sciences 29/74)
22. Chen SM, Chen HC, Chen SJ, Huang CY, Chen PY, Wu TW, Feng LY, Tsai HC, Lui TN, Hsueh C, Wei KC. MicroRNA-495 inhibits proliferation of glioblastoma multiforme cells by downregulating cyclin-dependent kinase 6. World Journal of Surgical Oncology. 2013 Apr; 11(1): 87. (SCI; IF2021=3.253; Surgery 108/282)
23. Chu PC, Chai WY, Hsieh HY, Wang JJ, Wey SP, Huang CY, Wei KC, Liu HL. Pharmacodynamic analysis of magnetic resonance imaging-monitored focused ultrasound-induced blood-brain barrier opening for drug delivery to brain tumors. Biomed Research International. 2013 Apr; 2013: 627496. (SCI; IF2021=3.246; Biotechnology & Applied Microbiology 90/159)
24. Yang HW, Liu HL, Li ML, Hsi IW, Fan CT, Huang CY, Lu YJ, Hua MY, Chou HY, Liaw JW, Ma CC, Wei KC. Magnetic gold-nanorod/ PNIPAAmMA nanoparticles for dual magnetic resonance and photoacoustic imaging and targeted photothermal therapy. Biomaterials. 2013 Jul; 34(22): 5651-5660. (SCI; IF2021=15.304; Materials science, biomaterials 4/98)
25. Yang HW, Hua MY, Hwang TL, Lin KJ, Huang CY, Tsai RY, Ma CC, Hsu PH, Wey SP, Hsu PW, Chen PY, Huang YC, Lu YJ, Yen TC, Feng LY, Lin CW, Liu HL*, Wei KC. Non-Invasive Synergistic Treatment of Brain Tumors by Targeted Chemotherapeutic Delivery and Amplified Focused Ultrasound-Hyperthermia Using Magnetic Nanographene Oxide. Advanced Materials. 2013 Jul; 25(26): 3605-3611. (SCI; IF2021=32.086; Chemistry, physical 4/165)
26. Yang HW, Lu YJ, Lin KJ, Hsu SC, Huang CY, She SH, Liu HL, Lin CW, Xiao MC, Wey SP, Chen PY, Yen TC, Wei KC*, Ma CC*. EGRF conjugated PEGylated nanographene oxide for targeted chemotherapy and photothermal therapy. Biomaterials. 2013 Sep; 34(29): 7204-7214. (SCI; IF2021=15.304; Materials science, biomaterials 4/98)
27. Liu HL, CK Jan, Chu PC, Hong JC, Lee PY, Hsu JD, Lin CC, Huang CY, Chen PY, and Wei KC, Design and Experimental Evaluation of a 256-Channel Dual-Frequency Ultrasound Phased-Array System for Transcranial Blood-Brain Barrier Opening and Brain Drug Delivery, IEEE Transactions on Biomedical Engineering, Vol.61, No. 4, pp.1350-1360, 2014 (SCI; IF2019=4.756; Engineering, biomedical 37/98).
28. Yang HW, Huang CY, Lin CW, Liu HL, Huang CW, Liao SS, Chen PY, Hsu PW, Lu YJ, Wei KC, Ma CCM. Gadolinium-functionalized nanographene oxide as a nanocarrier for combined drug and microRNA delivery and magnetic resonance imaging. Biomaterials, 2014 Aug; 35(24): 6534-6542. (2014). (SCI; IF2021=15.304; Materials science, biomaterials 4/98). (Co-first author)
29. Liu HL, Huang CY, Chen JY, Wang HYJ, Chen PY, Wei KC. Pharmacodynamic and therapeutic investigation of focused ultrasound-induced blood-brain barrier opening for enhanced temozolomide delivery in glioma treatment. PLoS One. 2014 Dec; 9(12): e114311. (SCI; IF2021=3.752; Multidisciplinary sciences 29/74)
30. Wang JC*, Karmakar RS, Lu YJ, Huang CY, Wei KC. Characterization of Piezoresistive PEDOT:PSS Pressure Sensors with Inter-Digitated and Cross-Point Electrode Structures. Sensors. 2015 Jan; 15(1): 818-831. (SCI; IF2021=3.847; Instruments & instrumentation 19/64)
31. Chen PY, Hsieh HY, Huang CY, Lin CY, Wei KC, Liu HL. Focused ultrasound-induced blood-brain barrier opening to enhance interleukin-12 delivery for brain tumor immunotherapy: a preclinical feasibility study. Journal of Translational Medicine. 2015 Mar; 13: 93. (SCI; IF2021=8.448; Medicine, research & experimental 25/139)
32. Lin CW, Wei KC, Liao SS, Huang CY, Sun CL, Wu PJ, Lu YJ, Yang HW*, Ma CC. A reusable magnetic graphene oxide-modified biosensor for vascular endothelial growth factor detection in cancer diagnosis. Biosensors & Bioelectronics. 2015 May; 67: 431-437. (SCI; IF2021=12.545; Electrochemistry 3/30)
33. Lin CY, Hsieh HY, Pitt WG, Huang CY, Tseng IC, Yeh CK, Wei KC, Liu HL. Focused ultrasound-induced blood-brain barrier opening for non-viral, non-invasive, and targeted gene delivery. Journal of Controlled Release. 2015 Aug; 212: 1-9. (SCI; IF2021=11.467; Pharmacology & pharmacy 12/279)
34. Yeh WL, Lin HY, Huang CY, Huang BR, Lin C, Lu DY, Wei KC. Migration-prone glioma cells show curcumin resistance associated with enhanced expression of miR-21 and invasion/ anti-apoptosis-related proteins. Oncotarget. 2015 Nov; 6(35): 37770-37781
35. Li SS, Lin CW, Wei KC, Huang CY, Hsu PH, Liu HL, Lu YJ, Lin SC, Yang HW, Ma CC. Non-invasive screening for early Alzheimer's disease diagnosis by a sensitively immunomagnetic biosensor. Scientific Reports. 2016 Apr; 6: 25155. (SCI; IF2021=4.997; Multidisciplinary sciences 19/74)
36. Lin CY, Hsieh HY, Chen CM, Wu SR, Tsai CH, Huang CY, Hua MY, Wei KC, Yeh CK, Liu HL. Non-invasive, Neuron-Specific Gene Therapy by Focused Ultrasound-Induced Blood-Brain Barrier Opening in Parkinson's Disease Mouse Model. Journal of Controlled Release. 2016 Aug; 235: 72-81. ((SCI; IF2021=11.467; Pharmacology & pharmacy 12/279)
37. Wei KC, Lin FW, Huang CY, Ma CC, Chen JY, Feng LY, Yang HW. 1,3-Bis(2-chloroethyl)-1- nitrosourea-loaded bovine serum albumin nanoparticles with dual magnetic resonance– fluorescence imaging for tracking of chemotherapeutic agents. International Journal of Nanomedicine. 2016 Aug; 11: 4065-4075. (SCI; IF2021=7.033; Pharmacology & pharmacy 62/361)
38. Liu HL, Hsu PH, Lin CY, Huang CW, Chai WY, Chu PC, Huang CY, Chen PY, Yang LY, Kuo JS, Wei KC. Focused Ultrasound Enhances Central Nervous System Delivery of Bevacizumab for Malignant Glioma Treatment. Radiology. 2016 Oct; 281(1): 99-108. (SCI; IF2021=29.146; Radiology, nuclear medicine & medical imaging 1/136)
39. Fan CH, Chang EL, Ting CY, Lin YC, Liao EC, Huang CY, Chang YC, Chan HL, Wei KC, Yeh CK. Folate-conjugated gene-carrying microbubbles with focused ultrasound for concurrent blood-brain barrier opening and local gene delivery. Biomaterials. 2016 Nov; 106: 46-57. (SCI; IF2021=15.304; Materials science, biomaterials 4/98)
40. Chang EL, Ting CY, Hsu PH, Lin YC, Liao EC, Huang CY, Chang YC, Chan HL, Chiang CS, Liu HL, Wei KC, Fan CH, Yeh CK. Angiogenesis-targeting microbubbles combined with ultrasound-mediated gene therapy in brain tumors. Journal of Controlled Release. 2017 Jun; 255: 164-175. (SCI; IF2021=11.467; Pharmacology & pharmacy 12/279)
41. Lin FW, Chen PY, Wei KC, Huang CY, Wang CK, Yang HW. Rapid In Situ MRI Traceable Gel-forming Dual-drug Delivery for Synergistic Therapy of Brain Tumor. Theranostics. 2017 Jun; 7(9): 2524-2536. (SCI; IF2021=11.600; Medicine, research & experimental 13/139)
42. Chen PY, Yeh CK, Hsu PH, Lin CY, Huang CY, Wei KC, Liu HL. Drug-carrying microbubbles as a theranostic tool in convection-enhanced delivery for brain tumor therapy. Oncotarget. 2017 Jun; 8(26): 42359-42371.
43. Liu YS, Lin HY, Lai SW, Huang CY, Huang BR, Chen PY, Wei KC, Lu DY. MiR-181b modulates EGFR-dependent VCAM-1 expression and monocyte adhesion in glioblastoma. Oncogene. 2017 Aug; 36(35): 5006-5022. (SCI; IF2021=8.756; Genetics & heredity 16/175)
44. Lin CY, Li RJ, Huang CY, Wei KC, Chen PY. Controlled release of liposome-encapsulated temozolomide for brain tumour treatment by convection-enhanced delivery. Journal of Drug Targeting. 2018 Apr; 26(4): 325-332. (SCI; IF2021=5.016; Pharmacology and pharmacy 76/279)
45. Lin TY, Wei KC, Ju SP, Huang CY, Yang HW. Diagnosis by simplicity: an aptachip for dopamine capture and accurate detection with a dual colorimetric and fluorometric system. Journal of Materials Chemistry B. 2018 May; 6(20): 3387-3394. (SCI; IF2021=7.571; Materials science, biomaterials 14/53)
46. Chen CH, Chen PY, Lin YY, Feng LY, Chen SH, Chen CY, Huang YC, Huang CY, Jung SM, Chen LY, Wei KC. Suppression of tumor growth via IGFBP3 depletion 1 as a potential treatment in glioma. Journal of Neurosurgery. 2019 Jan 1:1-12 (SCI; IF2021=5.526; Surgery 23/213)
47. Pang HH, Huang CY*, Chu YW, Lin CJ, Zhou ZL, Shiue YL, Wei KC, Yang HW. Bioengineering fluorescent virus-like particle/RNAi nanocomplexes act synergistically with temozolomide to eradicate brain tumors. Nanoscale. 2019 11:8102-8109 (SCI; IF2021=8.307, Physics, applied 23/161) (Co-first author)
48. Pang HH, Chen PY, Wei KC, Huang CW, Shiue YL, Huang CY*, Yang HW. Convection-enhanced delivery of a virus-like nanotherapeutic agent with dual-modal imaging for besiegement and eradication of brain tumors. Theranostics. 2019; 9:1752-1763 (SCI; IF2021=11.600; Medicine, research & experimental 13/139) (Co-corresponding author)
49. Lin CJ, Lin CY, Lin YT, Huang CY, Wei KC, Chen JC, Lee-Chen GJ, Liu HL*. Microbubble-facilitated ultrasound pulsation promotes direct α-synuclein gene delivery. Biochemical and Biophysical Research Communications. 2019 Sep; 517(1): 77-83. (SCI; IF2021=3.322; Biophysics 39/72)
50. Lin CY, Tsai CH, Feng LY, Chai WY, Lin CJ, Huang CY, Wei KC, Yeh CK, Chen CM*, Liu HL*. Focused ultrasound-induced blood brain-barrier opening enhanced vascular permeability for GDNF delivery in Huntington's disease mouse model. Brain Stimulation. 2019 Sep-Oct; 12(5): 1143-1150. (SCI; IF2021=9.184; Clinical neurology 17/212)
51. Chen PY, Wu CYJ, Fang JH, Chen HC, Feng LY, Huang CY, Wei KC, Fang JY, Lin CY*. Functional Change of Effector Tumor-Infiltrating CCR5+CD38+HLA-DR+CD8+ T Cells in Glioma Microenvironment. Frontiers in Immunology. 2019 Oct; 10: 2395 (SCI; IF2021=8.787; Immunology 35/162)
52. Wu CY, Chen CH, Lin CY, Feng LY, Lin YC, Wei KC, Huang CY, Fang JY, Chen PY. CCL5 of glioma-associated microglia/macrophages regulates glioma migration and invasion via calcium-dependent matrix metalloproteinase-2. Neuro-Oncology. 2020 Feb; 22(2): 253-266. (SCI; IF2021=13.029; Clinical neurology 8/212)
53. Li NS, Chen YT, Hsu YP, Pang HH, Huang CY, Shiue YL, Wei KC*, Yang HW*. Mobile healthcare system based on the combination of a lateral flow pad and smartphone for rapid detection of uric acid in whole blood. Biosensors & Bioelectronics. 2020 Sep; 164: 112309. (SCI; IF2021=12.545; Electrochemistry 3/30)
54. Pang HH, Ke YC, Li NS, Chen YT, Huang CY, Wei KC, Yang HW. A new lateral flow plasmonic biosensor based on gold-viral biomineralized nanozyme for on-site intracellular glutathione detection to evaluate drug-resistance level. Biosensors & Bioelectronics. 2020 Oct; 165: 112325. (SCI; IF2021=12.545; Electrochemistry 3/30)
55. Hsu WL1, Huang CY1, Hsu YP, Hwang TL, Chang SH, Wang HYJ, Feng LY, Tzou SJ, Wei KC, Yang HW. On-skin glucose-biosensing and on-demand insulin-zinc hexamers delivery using microneedles for syringe-free diabetes management. Chemical Engineering Journal. 2020 Oct; 398: 125536. (SCI; IF2021=16.744; Engineering, chemical 4/143) (co-first author)
56. Chen KT, Chai WY, Lin YJ, Lin CJ, Chen PY, Tsai, HC, Huang CY, Kuo JS, Liu HL, Wei KC. Neuronavigation-guided focused ultrasound for transcranial blood-brain-barrier opening and immunostimulation in brain tumors. Science Advances. 2020, 7: eabd0772. (SCI; IF2021= 14.980, Multidisciplinary sciences, 7/135)
57. Chen CH, Lin YJ, Lin YY, Lin CH, Feng LY, Chang IYF, Wei KC, Huang CY*. Glioblastoma primary cells retain the most copy number alterations that predict poor survival in glioma patients. Frontiers in Oncology. 2021 Apr. 11:1388 (SCI; IF2021= 5.738, Oncology, 78/245) (Corresponding author)
58. Huang CW, Chuang CP, Chen YJ, Wang HY, Lin JJ, Huang CY, Wei KC, Huang FT*. Integrin α2β1-targeting ferritin nanocarrier traverses the blood-brain barrier for effective glioma chemotherapy. Journal of Nanobiotechnology. 2021 Jun; 19: 180 (SCI; IF2021=9.429; Biotechnology & applied microbiology 14/159)
59. Tsai HC, Wei KC, Chen PY, Huang CY, Chen KT, Lin YJ, Cheng HW, Huang CH, Wang HT*. Receptor-Interacting Protein 140 Enhanced Temozolomide-Induced Cellular Apoptosis Through Regulation of E2F1 in Human Glioma Cell Lines. Neuromolecular Medicine. 2022, 24: 113-124 (SCI; IF2021=4.103; Neurosciences 123/275)
60. Chen CH, Wei, KC, Liao, WC, Lin YY, Chen HC, Feng LY, Liu CH, Huang CY, Chen KT, Wu CS, Chang YS, Yu JA Chang IYF. Prognostic value of an APOBEC3 deletion polymorphism for glioma patients in Taiwan. Journal of Neurosurgery. 2022 Sep 23:1-13 (SCI; IF2021=5.526; Surgery 23/213)
61. Lin YJ, Huang CY, Shen YC, Wei KC, Chuang CC, Hsu PW, Huang YC, Hwang TL, Chen PY. A manzamine-derived compound as a potential therapeutic agent for glioma by inducing apoptosis and cell cycle arrest. American Journal of Cancer Research. 2022; 12 (4): 1740-1751 (SCI; IF2021=5.942; Oncology 71/245)
62. Huang CY, Tsai PJ, Wu HW, Chen IT, Wang HYJ. Quantitative analyses and validation of phospholipids and sphingolipids in ischemic rat brains. Metabolites, 2022, 12(11), 1075. (SCI; IF2021=5.581, Biochemistry & Molecular biology 90/297) (First author)
63. Wang HYJ*, Huang CY*, Wei KC, Hung KC. A mass spectrometry imaging and lipidomic investigation reveals aberrant lipid metabolism in the orthotopic mouse glioma. Journal of Lipid Research, 2022: 100304. (SCI; IF2021=6.676, Biochemistry & molecular biology 72/322) (co-first author)
專利
1.華沐怡、楊閎蔚、蔡榮源、魏國珍、陳品元、黃瓊瑩, 用於抑制/治療腫瘤之磁性奈米複合物及其製備方法, 中華民國專利, 專利號碼: I389702, 專利核准日期: 2013/03-2029/11
2.賴朝松、魏國珍、王哲麒、華沐怡、盧郁仁、黃瓊瑩、蘇聖凱, “體內手術用之壓力監測系統,” 中華民國專利, 專利號碼: I536950, 公告日: 2016/06/11, 專利期限: 2012/07/06~2032/07/05
完整個人履歷(學歷、經歷、殊榮、學會或專業認證…等)
主要學歷
高雄醫學大學 藥學系 學士 1988/9至1991/6
高雄醫學大學 基礎醫學研究所藥理學組 碩士 1992/9至1994/6
國立陽明大學 熱帶醫學研究所 博士 1997/9至2005/6
現職及與專長相關之經歷
2006/1/1-present 長庚紀念醫院神經外科，博士後研究員
2005/12 浙江大學沃森基因組科學研究院 基因組科學生物訊息研習班
2004/01-2004/05 Department of Animal Health and Biomedical Sciences, School of Veterinary Medicine, University of Wisconsin Madison, Wisconsin, U.S.A.訪問學者
2003/01-2003/02 Department of Genetics, Case Western Reserve University, Ohio, U.S.A.訪問學者
1995/09-1998/08 長庚大學醫學系，專任教學助教
1992/08-1993/08 高雄醫學大學附設中和紀念醫院內分泌科，研究助理
獲獎紀錄
94年國立陽明大學優秀博士論文獎
94年台灣寄生蟲會范秉真教授寄生蟲學研究論文獎
第11屆台塑關係企業應用技術研討會研發論文競賽學校組優良獎