Carothers Research Group
RNA synthetic biology and metabolic engineering
The Carothers Research Group integrates RNA aptamer device design, dynamic control system modeling, and CRISPR-Cas network engineering for applications in synthetic biology. Our main goals are to understand biological design principles and engineer metabolic systems to produce industrially- and medically-important chemicals and materials.
James is the Dan Evans Career Development Associate Professor of Chemical Engineering, Adjunct Associate Professor of Bioengineering, and Member of the Molecular Engineering & Sciences Institute (MolES) and Center for Synthetic Biology (CSB) at the University of Washington. James was a founding council member of the Engineering Biology Research Consortium (EBRC).
Previously, James was a postdoctoral fellow and research scientist with Jay D. Keasling at UC Berkeley and the DOE Joint BioEnergy Institute. James was a graduate student at Harvard, where he earned a Ph.D. with Jack W. Szostak. James has a B.S. in Molecular Biophysics and Biochemistry from Yale. He has received the University of Washington Presidential Innovation Award and the Alfred P. Sloan Research Fellowship and work in the laboratory is currently supported by grants from the DOE, NSF and private industry.
Outside the lab, he was a fellow of the Silicon Valley Startup Leadership Program (SLP), and enjoys Seattle's museums, backpacking, snowboarding, mountain biking, and spending time with his family.