BPC-157 Peptide: What It Is and What the Record Shows

BPC-157 is a peptide of 15 amino acids with the sequence Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val. The records also call it Bepecin and PL-14736. Curo's recovery and regenerative research catalog lists a BPC-157 5mg vial.

What is BPC-157?

BPC stands for Body Protection Compound. A 1993 overview described a gastric juice peptide named BPC and a 15 amino acid fragment of it, BPC 157, that the authors thought was essential for its activity. A 2011 study of rat tendon cells describes BPC-157 as a partial sequence of a compound "discovered in and isolated from human gastric juice". Sources: 1993 overview of BPC and BPC 157, PMID 8298609 and 2011 rat tendon-cell study, PMID 21030672.

FDA's briefing document for its July 2026 advisory committee, dated May 11, 2026, says: "BPC-157 is also known as Bepecin or PL-14736, which is a peptide that is reported to be comprised of 15 amino acids." Source: FDA briefing document, BPC-157-related bulk drug substances.

Which identifiers belong to BPC-157?

• PubChem compound identifier (CID) 9941957.

• Molecular formula C62H98N16O22 and molecular weight 1419.5 g/mol.

• CAS number 137525-51-0 for the free base.

• FDA unique ingredient identifier (UNII) 8ED8NXK95P for the free base and PAR2FC72XP for the acetate salt.

• Other names in the records: PL-10, PLD-116 and PL-14736.

Sources: PubChem BPC-157 record, CID 9941957, FDA UNII record 8ED8NXK95P and the identifier table in the FDA briefing document.

These identifiers describe the reference compound. They do not describe what is in a particular vial. The FDA UNII page states: "UNII availability does not imply any regulatory review or approval."

Is BPC-157 one substance?

The name BPC-157 covers more than one form. FDA's briefing document says BPC-157 "is a common name and not a United States Adopted Name (USAN)" and that "FDA has encountered multiple salts, and derivatives, including different active moieties, sold commercially under the same common name." The document lists BPC-157 (free base) and BPC-157 acetate with different UNII and CAS numbers and calls them different bulk drug substances. Source: FDA briefing document, section II.A.

The primary-source ledger for this site is a Google Doc: Open the BPC-157 source ledger.

What has been studied?

Most published work uses rats, other animals or cultured cells. A 2025 systematic review searched the literature through June 3, 2024 and included 36 studies, 35 of them preclinical and one clinical. Source: 2025 systematic review in the HSS Journal, PMID 40756949. The BPC-157 research page lists the studies by model, the small human reports and the registry records.

Is BPC-157 an approved drug?

FDA's briefing document dated May 11, 2026 states that there is "no applicable United States Pharmacopeia (USP) or National Formulary (NF) drug substance monograph for BPC-157 (free base) or its acetate form, and neither is a component of an FDA-approved drug." The BPC-157 FDA status page gives that record with the other FDA dates and the WADA listing.

Is BPC-157 the same as the BPC-157 and TB-500 combination?

No. BPC-157 is one peptide. TB-500 is a different substance, and FDA's meeting page lists the two as separate entries. The combination has its own research record, which the Wolverine peptide site covers.

Where do researchers find BPC-157 material and lot documents?

Lot reports are grouped by lot number in Curo's lot certificate library. The BPC-157 for sale page explains how to read a listing against the identifiers above.

BPC-157 questions

What does BPC-157 stand for?

BPC stands for Body Protection Compound, and BPC 157 is the name the 1993 authors gave to the 15 amino acid fragment. Source: 1993 overview, PMID 8298609.

Is BPC-157 the same as PL-14736?

The records use both names for one peptide. FDA's briefing document says BPC-157 "is also known as Bepecin or PL-14736", and PubChem lists PL-14736 as a synonym of CID 9941957. Sources: FDA briefing document and PubChem BPC-157 record, CID 9941957.

Is there evidence for BPC-157 in people?

A 2025 narrative review states that "human data are extremely limited." The BPC-157 research page lists the three small human reports and the registry records. Source: 2025 narrative review, PMID 40789979.