Unique from other brain disorders, traumatic brain injury (TBI) generally results from a discrete biomechanical event that induces rapid head movement. The large size and high organization of the human brain makes it particularly vulnerable to traumatic injury from rotational accelerations that can cause dynamic deformation of the brain tissue. Therefore, replicating the injury biomechanics of human TBI in animal models presents a substantial challenge, particularly with regard to addressing brain size and injury parameters. Here we present the historical development and use of a porcine model of head rotational acceleration. By scaling up the rotational forces to account for difference in brain mass between swine and humans, this model has been shown to produce the same tissue deformations and identical neuropathologies found in human TBI. The parameters of scaled rapid angular accelerations applied for the model reproduce inertial forces generated when the human head suddenly accelerates or decelerates in falls, collisions, or blunt impacts. The model uses custom-built linkage assemblies and a powerful linear actuator designed to produce purely impulsive non-impact head rotation in different angular planes at controlled rotational acceleration levels. Through a range of head rotational kinematics, this model can produce functional and neuropathological changes across the spectrum from concussion to severe TBI. Notably, however, the model is very difficult to employ, requiring a highly skilled team for medical management, biomechanics, neurological recovery, and specialized outcome measures including neuromonitoring, neurophysiology, neuroimaging, and neuropathology. Nonetheless, while challenging, this clinically relevant model has proven valuable for identifying mechanisms of acute and progressive neuropathologies as well as for the evaluation of noninvasive diagnostic techniques and potential neuroprotective treatments following TBI.
She was born and raised in Phoenix, Arizona and had previously worked as a model for American Apparel. She released "Experience", her first non-album single independently in 2014.[2] She additionally worked as a backup dancer on The Yeezus Tour for American rapper Kanye West, where he discovered her music and signed her to his GOOD Music label "immediately".[3]
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Hill began modelling at the age of 16 after being discovered by a wedding photographer.[12] She moved to Los Angeles after high school to pursue a modelling career, which led to her becoming the face for American Apparel.[11] She got into music when she met a director named Stephen Garnett, who later directed the video for her first non-album single release, Experience.[11][13] Regarding her modelling career, Hill stated that she never felt passionate about it. In an interview with NY Mag, she was quoted as saying, "It wasn't something I really wanted to do; it was something that was there, so I went after it."[12]
Hello Fall 2016! Time sure has flown! In 2016 NiK Kacy Footwear had the opportunity to participate in a series of amazing fashion shows (which you can check out more on our blog page.) We even went international at Toronto Fashion Week for SuperButch in May! Thanks to amazing organizers like Dinah Thorpe, Heather Blom, Jack Jackson and many others, we got to show off our collection on a Canadian runway! Here are some pics with some of our favorite designers Kirrin Finch's Kelly and Laura Moffat and Thuy Nguyen of Thuy Custom Clothier. Our Fortune collection in a circle worn by our models, some on stage photos and finally all our models getting pumped for the runway!
In September, we had the honor of being part of DapperQ's iD Queer Style Fashion Show, kicking off NY Fashion Week, co-presenting with Sharpe Suiting our custom designs and giving the audience a taste of NiK Kacy's next collection, Destiny, a series of formal shoes, boots, and high heels. Here's a photo of our friend/model, Mike Bazer who flew in all the way from Chile once again to walk for us. (We
Here is most of our crew of models, tailors, friends with Leon of Sharpe Suiting and NiK Kacy post show. Can you tell we were super high of the energy of the night? (Our models for the night: Marcia Alvarado, Tiq Milan, Landon Cider, Mike Bazer, Kiralee Hiyashi, Jolaina Peltier, Aviya Eschenazi, Sannie Pedersen).
The check boxes on the map are the locations where model output statistics forecasts are produced. For the vast majority of sites, these locations will be at airports. View all MOS forecasts from the short-range GFS model (called MAV), extended-range GFS model (called MEX) and NAM (called MET). Or get MOS guidance by list for Delaware, Maryland, New Jersey, Pennsylvania, Virginia or West Virginia.
Furthermore, we analysed the intracellular metabolite fractions of the Caco-2 cells to determine the induced effects as a result of the co-culture regimes involving LGG and B. caccae (Fig. 4c). Analogous to the transcriptional response, the intracellular metabolite fractions of the Caco-2 cells were significantly altered in response to the consortium co-culture as compared with the cells co-cultured solely with LGG (Fig. 3c; Supplementary Table 7). Our results demonstrate that the HuMiX model is capable of capturing transcriptional and metabolic responses of the human epithelial cells in response to changes in the composition of the co-cultured microorganisms.
P.S., M.E., F.Z. and P.W. conceptualized the HuMiX model. P.S., J.V.F., M.S.D., K.G., A.F., M.N., M.E., C.S.-D., F.Z. and P.W. developed the experimental plan. P.S. and M.E. prototyped the device. P.S., J.V.F., M.N., K.G. and A.F. conducted the co-culture experiments. C.J. conducted metabolite analyses. P.S., J.V.F., E.G. and P.W. analysed the data. P.S., J.V.F. and P.W. wrote the manuscript. All authors commented on and approved the final version of the manuscript.
Societally, diversity is expanding in many ways, and a growing number of models who identify as mixed are pushing back against being labeled as just one ethnicity or the other. Cleveland herself is African American, Irish, Cherokee, English, Scottish and German.
Born and raised in Phoenix, Arizona, Hill began modeling at the age of 16 after being discovered by a wedding photographer. Moved to LA, she worked as a model for American Apparel. Kacy is now a singer-songwriter, currently signed to Kanye West's GOOD Music.
According to Kacy Hill, music kind of just fell into her lap. While working as an American Apparel model, she stumbled into songwriting when a photographer on one of her shoots asked her to join him in the studio. Together they wrote and shot the video for "Experience," which caught the attention of Kanye West while she was working on his Yeezus tour as a background model. She returned home with a deal with G.O.O.D. Music, and today she released her debut EP Bloo, and you can cop it here.
Pop musician and singer-songwriter Conan Gray will perform at 8 p.m. Oct. 1 at the IU Auditorium on the North American leg of his Superache Tour. Singer-songwriter, producer and former model Kacy Hill will perform alongside Gray at the concert.
Kacy Hill has signed to G.O.O.D. Music, the label founded by Kanye West in 2004. Previously, Hill worked as a model for American Apparel and a backup dancer for Kanye on his Yeezus tour. The signing was initially announced by Def Jam via Twitter.
Functional Data Analysis is often used in the study of data that exists over a continuum, such as time. There are two datasets that will be considered here. For the first study we have a dataset on the efficacy of a lobectomy in reduction or elimination of epileptic seizures in patients. After an initial analysis of the dataset from a multinomial model perspective, we found that there were outliers in our dataset. From there, we considered a Multinomial Mixture Model to aid in the detection of outliers. In our second dataset we are considering a social robotics dataset where the purpose is to aid in the integration of students from diverse backgrounds into US school systems. We use Univariate Functional Data Analysis on our dataset before moving on to consider Multivariate Functional Data Analysis with the addition of Seemingly Unrelated Regression to our analysis and estimation of our Bayesian Estimates.
Just curious -- how did you find her? I did the usual things, googled variations of "who is this American Apparel model?", ran various images through google image search, hoping they'd turn up elsewhere. But no luck.
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Check out Kacy Lane posing naked on the wreckage of a home; her natural physique contrasts starkly with the ruined setting, making it appear that she is extremely delicate and susceptible. This adult model from Latvia, who is now 22 years old, began taking nude photographs when she was only 19 years old, so she is not new to displaying her assets.However, she should not be confused with Kacy Lane, an American actress who has appeared in pornographic films. The fact that this Kacy is flaunting a large hole in her behind suggests that she has ambitions of working in the adult film industry. Believe us, you won't want to pass up the opportunity to check out these smokin' photos! be457b7860
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