Workshop

 on

Computational Approaches for Blood Flow in Arterial Networks - CABFAN 2024

IIT Kanpur

20th-23rd March 2024

Sponsored by: National Supercomputing Mission (DST)

Workshop Scope and Relevance

There has been tremendous progress in CFD simulations in patient-specific geometries over the past two decades due to an enormous increase in computing power. Simultaneously, the modelling approaches of blood as a fluid have also evolved in the continuum and mesoscale limits. This workshop will teach different aspects of the continuum approach through theoretical and hands-on sessions. The workshop will also introduce some elements of mesoscale modelling of blood. It will encompass various tools, backgrounds and methods of continuum modelling using CFD. Through detailed hands-on sessions, the participants will also be exposed to solving related problems using commonly used CFD tools. Firstly, the details and background of CFD methods will be explained. Next, the complete process of starting with actual CT-scan data and building patient-specific geometry for CFD simulations will be covered. A detailed exposure to the solution of such problems using CFD, by setting up boundary conditions and governing equations in CFD packages, will be provided by lectures and hands-on sessions, apart from continuum and CFD, mesoscale advancements, especially those of Dissipative particle dynamics (DPD) model of RBCs would also be covered in detail. All the advancements in RBC and blood rheology will also be shown. It is expected that any student with an essential engineering/science background attending the workshop would be able to perform simulations of blood flow in patient-specific geometries, starting from CT-scan data. They would also have adequate impressions of various aspects of blood rheology and mesoscale techniques towards modelling such flows. They would also have some idea to select the correct blood model for any given application. This workshop is expected to be helpful for skill enhancement in this emerging field, where medical professionals and engineers can collaborate to solve blood flow-related problems in a patient-specific manner.


CT-Scan Machine at LPS institute of cardiology & Cardiac Surgery  and Real Human circulatory system obtained from LPS institute of cardiology & Cardiac Surgery 

The arterial geometry was reconstructed separately for the head/neck and the rest of the body using CT image data from two subjects. Source: Xiao et al.

Registration Closed

Workshop Plan 

The workshop will be spread over four days, consisting of lectures coupled with hands-on sessions whose contents are directly related to the lectures. Thus, this will closely follow the active learning philosophy, where the theory is closely linked with practical sessions. The material will be spread over seven different topics. The students will first learn about CFD fundamentals and the usage of these techniques in biomedical applications. Next, they will learn to build the patient-specific geometry for CFD of blood flow, starting from CT scan files. Following this, they would learn about setting up the equations for CFD simulations, coupled with hands-on sessions that will talk about setting up using solvers and obtaining the final solution (with some post-processing). Hands-on sessions will focus on more straightforward examples so students can grasp this topic well. Next, they will be introduced to Openfoam simulations of patient-specific geometries, where some simpler but still patient-specific problems will be handled. Independent lectures would tell the participants about medical imaging and full-body simulations.


Next, there will be sessions on three related aspects, which complete the understanding. One is about parallel programming aspects of HPC, which form the backbone of simulations in modern HPC clusters. Next is a lecture on various blood rheology models suitable for different applications. Finally, some mesoscale simulations will be introduced, focusing on RBC modelling. These will also be coupled with hands-on sessions for a holistic understanding.


Course Coordinators

Dr. Indranil Saha Dalal

Professor, Department of Chemical Engineering

Indian Institute of Technology. Kanpur

Kanpur 208016 UP India

Email - indrasd@iitk.ac.in

Dr. K. Muralidhar

Professor, Department of Mechanical Engineering

Indian Institute of Technology. Kanpur

Kanpur 208016 UP India

Email - kmurli@iitk.ac.in

  Student Coordinator

Rishi Kumar

PhD Scholar, Department of Chemical Engineering

Indian Institute of Technology. Kanpur

Kanpur 208016 UP India

Email - rishik21@iitk.ac.in

Contact: +91 8279785682