you can give the path to a local NR database in a location file. The Galaxy Blast wrappers will look into such files and will offer this option to the users. Please have a look at the documentation: _blast#installation

In bioinformatics, BLAST (basic local alignment search tool)[3] is an algorithm and program for comparing primary biological sequence information, such as the amino-acid sequences of proteins or the nucleotides of DNA and/or RNA sequences. A BLAST search enables a researcher to compare a subject protein or nucleotide sequence (called a query) with a library or database of sequences, and identify database sequences that resemble the query sequence above a certain threshold. For example, following the discovery of a previously unknown gene in the mouse, a scientist will typically perform a BLAST search of the human genome to see if humans carry a similar gene; BLAST will identify sequences in the human genome that resemble the mouse gene based on similarity of sequence.




Blast Download Database