Biomaterials, biomimetic nanomedicine and theranostic applications
University of Granada
The BIOMIMED-Lab is dedicated to the development of nanomaterials and biomaterials for biomedical applications, with a strong focus on nanomedicine, nanotoxicology, and biomimetic systems. The group develops advanced platforms for targeted cancer therapy and diagnosis, including cell membrane-coated nanoparticles and three-dimensional scaffolds for tissue engineering. In parallel, it investigates the fundamental mechanisms of bionanointeractions in complex biological environments, such as biomolecular corona formation and nanoparticle behaviour at the cellular level, aiming to bridge basic research with translational biomedical applications.
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The emerging technology of cell membrane coating has become a novel concept for designing NPs, and it has been leveraged to significantly enhance the functionality of nanoparticulate platforms. In this lab, our goal is to design cell membrane coating nanosystem as a potential tool for cancer treatment and understand the benefits and drawbacks of this type of stealth coating by using well-established and reliable physicochemical characterization techniques.
In our laboratory, we specialize in nanomedicine research, with a specific focus on the study of nanobiointeractions. We explore the application of nanotechnologies for the development of innovative approaches in the diagnosis and treatment of diseases, placing particular emphasis on understanding the intricate interactions at the nanoscale between designed materials and biological systems. Our objective is to contribute to the advancement of science and medicine by gaining a detailed understanding of nanoscale interactions, thereby providing a solid foundation for the design of more effective and precise therapies and diagnostics.
Dedicated to cutting-edge research, our focus extends to the exploration of 3D scaffolds for theranostics. Here, in collaboration with colleagues we actively develop and investigate innovative three-dimensional structures such as microgel platforms and magnetic hydrogels designed for theranostic applications and tissue regeneration.
Within the realm of nanomedicine, our research is dedicated to understanding the processes involved in the transport of nanomaterials through biological barriers. This involves a comprehensive exploration of the dynamic interplay between different nanomaterials and models of biological barriers including the blood-brain barrier and the intestinal barrier, seeking to understand the factors influencing their transport efficiency and potential applications.
Values and Research Philosophy
We believe in a way of doing science grounded in care, ethics, and shared learning.
As PI, I conceive the lab as a space for both intellectual and personal growth, where the training and development of students and early-career researchers are central. I understand scientific supervision as an ethical responsibility that involves supporting learning processes, fostering autonomy, respecting individual rhythms, and promoting a collaborative, inclusive, and respectful working environment.
We are committed to rigorous and socially responsible research, where scientific excellence is measured not only by publications or quantitative indicators, but also by the ability to generate responsible knowledge, foster healthy human relationships, and create meaningful opportunities for the people who are part of the group.