Division of Mechanical Science and Engineering, Graduate School of Natural Science and Technology, Kanazawa University

Bioengineering Laboratory


Research subjects

The mission of this laboratory is to create novel and effective methodologies of treatment, prevention, and diagnosis for osteoporosis from the aspect of bioengineering. For the treatment, tissue-engineered bones with highly-mechanocompatible with bone tissue are studied utilizing techniques of tissue-engineering. For the prevention, we focus on electromyostimulation on as a promising non-pharmacological intervention, feasible for elderly people, to prevent osteoporosis. For the diagnosis, we are developing an optical bone densitometer utilizing infrared laser diodes, which smaller, safer, and easier to operate than the conventional X-ray device. To these ends, cell culture, animal experiments, and computer simulations are performed in our laboratory.

Education policy

Acquiring broad knowledge is required to accomplish a bioengineering research. Knowledge of biology and medicine are important in applications of the research to clinical and engineering fields. Several research groups are organized in the laboratory and each group presents the progress of research project in a lab meeting weekly. Small meetings with the professor are also held at any time and current problems are deeply discussed. Spontaneous actions are required for all students based on thier research plan, managing time and relationships with other lab members.

Daily life in our laboratory

All information about our laboratory such as lab meeting schedule, experimental protocols, and graduation/master theses are accessible in our private laboratory web site. All students use their own laptop computers in the laboratory, and access to Internet through the university Wi-Fi network. Workstation PCs are also available in our laboratory for various simulation, CAD, and image processing. To deal with animals and cells, the special knowledge and experimental skill are required for all the students.

Master theses in last 3 years

Development of optical bone densitometer

Study on non-linear osteoblastic response to physical stimulation

Evaluation of the mechanical properties of tissue-engineered bone under impact loading

Study on osteogenic effect of electrical muscle stimulation

Osteogenic effect of electromagnetic filed stimulation on an OVX rat

Improvement of mechanical properties of a tissue-engineered bone constructed with a calcinedbovine trabecular bone scaffold using electromagnetic field stimulation

Development of an optical device for monitoring of calcification in a tissue-engineered bone

Osteogenic effect of electrical muscle stimulation with random pulse train waveform

Study on osteogenic effect of electrical muscle stimulation

Study on promotion effect of electromagnetic filed with random pulse train on osteoblasticcalcification in vitro

Message from the professor

Technological innovations are often created in the border areas of established academic or engineering fields. Bioengineering is in the border area including mechanical engineering, medicine, biology, and material engineering and so on, in which our creativity is stimulated by the variety of concepts. Environmental diversity promotes our adaptability to the rapid-changing global society, recommending us to study broad knowledges, especially abroad.

Laboratory mail address: shigeo@se.kanazawa-u.ac.jp