Past lab members
Nathalia Lopes - visiting PhD student
Nathalia investigated the hypothesis that pathological epithelial-mesenchymal plasticity represents reactivation of a developmental process that does not occur in normal adult tissue.
Fay Pickering - LIDo DTP rotation PhD student
Fay studied modes of cell migration in development, health and disease. Epithelial-to-mesenchymal transition (EMT), in which epithelial cells acquire a migratory mesenchymal phenotype, occurs in development, in cancer, and in adult tissue regeneration. This process is heterogenous, and results in distinct and often interchangeable modes of migration including recognised mesenchymal and amoeboid states. Fay’s aimed to quantify migration in 3D models, beginning with migration of oral squamous cell carcinoma cells, with a view to using biophysical simulation models to elucidate general rules governing single and collective cell-migration in health, development and disease settings.
Fay graduated from University College London with a BSc in Biomedical Science in 2018. She is now pursuing a career in the medical communications industry.
Avik Sabui - MSc student
Project title: Targeting developmental epithelial-mesenchymal plasticity for cancer therapy, whilst sparing its regenerative counterpart.
Grace Gilmour - intercalating BSc student
Project title: Investigating a role for secreted signalling factors in determining cancer stem cell identity.
Olivia Knowles - intercalating BSc student and AFRUK summer student
Project title: Identification of a novel cancer stem cell sub-population in melanoma pathological specimens.
Merry Marcella - MSc student
Project title: Investigating the role of cancer stem cells in oral squamous cell carcinoma metastasis through the development of a 3D metastasis-on-a-chip microfluidic model.
Stephanie Lunt - AFRUK summer student
Project title: Characterization of cancer stem cell sub-populations in melanoma.