Brugada Electrocardiographic Indices Registry (BEIR)

Welcome to the Brugada Electrocardiographic Indices Registry (BEIR)

This project started as a single center study by Dr. Gary Tse and his team members who are based in Hong Kong, China. With the kind support of open-minded investigators from many countries, it promptly expanded to include different centers with expertise in managing Brugada patients. The aim of this project is to use different electrocardiographic indices for risk stratification in patients with Brugada ECG patterns.

What is the Brugada Syndrome?

Brugada Syndrome is a genetic cardiac ion channelopathy with chracteristic ECG patterns, predisposing to the development of syncopal symptoms, spontaneous ventricular tachy-arrhythmias and sudden cardiac death.

What is unique about our project?

We differ from other registries in four major respects:

  1. The investigators are taking an all inclusive stance, and welcome contributions from any interested investigators with relevant data to join our project. For example, we have researchers from all over the globe coming from centres of varying sizes.

  2. We particularly encourage new and junior researchers to join our project.

  3. We have recruited investigators from across the disciplines, such as pre-clinical electrophysiology, data science, clinical cardiology and electrophysiology, and epidemiology, to facilitate collaboration and cooperation.

  4. The goal is to utilize complex and higher dimensional analyses to facilitate risk prediction.

Who are the BEIR investigators?

Brazil Investigators

Dr. Leonardo Roever, MHS, PhD

Department of Clinical Research,

Federal University of Uberlândia, Uberlândia, MG, Brazil.

Cambodia Investigators

Dr. Yorn Uy, MD

Cardiac Electrophysiologist

Khmer Soviet Friendship Hospital

Phnom Penh, Cambodia

Canada Investigators

Dr. Adrian Baranchuk, MD, FACC, FRCPC

Professor of Medicine

Cardiac Electrophysiology and Pacing

Kingston General Hospital, Queen’s University

Kingston, Ontario, Canada

Dr. Benedict M Glover, MD, MB BCh BAO, MRCP

Associate Professor, Department of Medicine, University of Toronto

Ontario, Canada

Mr. Sohaib Haseeb, BSc (Hons.)

Medical Student

School of Health Sciences, Queen’s University

Kingston, Ontario, Canada

China Investigators

Dr. Jeffrey Chan, MD

Cardiac Electrophysiology Unit, Cardiovascular Analytics Group

Hong Kong, China-UK Collaboration

Dr. Dong Chang, MD, PhD

Professor and Director of Cardiac Electrophysiology Laboratory

Xiamen Cardiovascular Hospital, Xiamen, People’s Republic of China

Dr. Cheng Chen

Cardiology Resident

Department of Cardiology, The First Affiliated Hospital of Dalian Medical University, Dalian, People’s Republic of China

Dr. Yunfei Gu, MD

Consultant Cardiologist

Luoyang Central Hospital Affiliated to Zhengzhou University, Zhengzhou, People’s Republic of China

Dr. Dan Hu, MD, PhD, FACC, FAHA, FHRS

Professor

Department of Cardiology & Cardiovascular Research Institute, Renmin Hospital of Wuhan University, 238 Jiefang Road, Wuhan, 430060, People’s Republic of China.

Dr. Zhengrong Huang, MD, PhD

Professor

Department of Cardiology, The First Hospital of Xiamen Affiliated to Fujian Medical University, Xiamen, People’s Republic of China

Sharen Lee

Cardiac Electrophysiology Unit, Cardiovascular Analytics Group

Hong Kong, China-UK Collaboration

Dr. Guoliang Li, MD PhD

Chief Resident in Cardiology

Arrhythmia Unit, Department of Cardiovascular Medicine, First Affiliated Hospital of Xi’an Jiaotong University, No. 277 Yanta West Road, Xi’an 710061, People’s Republic of China

Dr. Xintao Li, MD

Consultant Cardiologist

The First People's Hospital of Changzhou, Changzhou, Jiangsu, People’s Republic of China. 213003

Dr. Fang Zhou Liu, MD, PhD

Consultant Cardiac Electrophysiologist

Guangdong Cardiovascular Institute, Guangdong

People’s Republic of China

Dr. Tong Liu, MD, PhD

Professor of Cardiology

Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular disease,

Department of Cardiology, Tianjin Institute of Cardiology, The Second Hospital of Tianjin Medical University,

Tianjin 300211, People’s Republic of China


Dr. Gary Tse, BA (Hons.), MBBS, MA, MPH, MHM, PhD, FESC, FACC, FSCAI, FHRS, FRCP (Glasg, Edin, Lond), FRCPCH, FFPH

Cardiac Electrophysiology Unit, Cardiovascular Analytics Group, Hong Kong, China-UK Collaboration

Distinguished Professor, Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular disease, Tianjin Institute of Cardiology, The Second Hospital of Tianjin Medical University

Honorary Professor, Xiamen Cardiovascular Hospital of Xiamen University

Guest Professorship in Cardiovascular Medicine, The First Affiliated Hospital of Dalian Medical University

People’s Republic of China

Dr. Qunshan Wang, MD, PhD

Professor

Shanghai Jiaotong University, Xinhua Hospital

People’s Republic of China

Dr. Qingpeng Zhang, PhD

Assistant Professor

School of Data Science, City University of Hong Kong,

Hong Kong, People’s Republic of China

Dr. Shaoying Zeng, MD

Professor and Consultant Paediatric Cardiologist

Guangdong Cardiovascular Institute,

Guangdong, People’s Republic of China

Dr. Jiandong Zhou

School of Data Science, City University of Hong Kong,

Hong Kong, People’s Republic of China

Colombia Investigators

Dr. Andres Felipe Miranda Arboleda

Universidad de Antioquia

Antioquia, Colombia

Germany Investigators

Dr. Eric Schulze-Bahr, MD

Professor

Department of Cardiovascular Medicine,

Institute for Genetics of Heart Diseases (IfGH),

University Hospital Münster, Germany

Dr. Sven Zumhagen, MD

Department of Cardiovascular Medicine,

Institute for Genetics of Heart Diseases (IfGH),

University Hospital Münster, Germany

Greece Investigators

Dr. George Bazoukis, MSc, MD

Second Department of Cardiology,

Laboratory of Cardiac Electrophysiology,

“Evangelismos” General Hospital of Athens,

Athens, Greece

Dr. Konstantinos Letsas, MD, FESC, FEHRA

Consultant Cardiologist

Second Department of Cardiology,

Laboratory of Cardiac Electrophysiology,

“Evangelismos” General Hospital of Athens,

Athens, Greece

Dr. Michael Spartalis, MD, FESC, FEHRA, FACC, CCDS, CEPS-A

Consultant Cardiologist

3rd Department of Cardiology, National and Kapodistrian University of Athens Medical School

Athens, Greece

India Investigators

Dr. Mukund Prabhu, MD, DM

Assistant Professor

Amrita Institute of Medical Sciences,

Ponekkara, Cochin

Mangalore, India

Dr. Maneesh Rai, MD, DM

Assistant Professor

Department of Cardiology

Kasturba Medical College,

Mangalore, India

Dr. Jayaprakash Shenthar, MD, PhD

Professor

Electrophysiology Unit Sri Jayadeva Institute of Cardiovascular Sciences and Research B G Road, 9th Block, Jayanagar, Bangalore - 560069 India

Dr Rajan Vashisht, MBBS, MD

Clinical interests: CCU (bedside echocardiography, TPI, IABP, central lines, ionotropes,Intubation, arterial monitoring), STEMI and NSTEMI risk stratification


Japan Investigators

Dr. Kengo Kusano, MD

Director,

Division of Arrhythmia and Electrophysiology,

Department of Cardiovascular Medicine,

National Cerebral and Cardiovascular Center,

Osaka, Japan

Dr. Takeshi Aiba, MD

Chief Physician,

Division of Arrhythmia and Electrophysiology,

Department of Cardiovascular Medicine,

National Cerebral and Cardiovascular Center,

Osaka, Japan

Dr. Tsukasa Kamakura, MD

Division of Arrhythmia and Electrophysiology,

Department of Cardiovascular Medicine,

National Cerebral and Cardiovascular Center,

Osaka, Japan

Mexico Investigators

Dr. Víctor Javier Ceseña Báez, MD

Fellow of Cardiology,

Hospital Christus Muguerza Alta Especialidad,

México

Dr. Manlio F. Márquez Murillo

Instituto Nacional de Cardiología “Ignacio Chávez”

Mexico City, Mexico

Dr. Jorge Francisco Herrera Orozco

Instituto Nacional de Cardiología “Ignacio Chávez”

Mexico City, Mexico

Dr. Ramon Alexander Hernandez Dominguez

Instituto Nacional de Cardiología “Ignacio Chávez”

Mexico City, Mexico

Dr. Bernardo Wise, MD

Associate Professor and Cardiac Electrophyisiologist

Christus Muguerza AE Hospital

Monterrey, Mexico

Nevetherlands Investigators

Dr. Natasja M.S. de Groot, MD, PhD

Professor of Cardiology

Cardiologist/Electrophysiologist, Chief of Translational Electrophysiology Unit

Erasmus MC, Rotterdam, Netherlands

Poland Investigators

Dr. Marek Jastrzebski, MD, PhD

First Department of Cardiology and Electrocardiology, Jagiellonia University, Collegium Medicum

Kraków, Poland

Dr. Pawel Matusik, MD, PhD

Institute of Cardiology, Jagiellonian University Medical College and the John Paul II Hospital,

Kraków, Poland

Paweł T. Matusik, MD, PhD, FEHRA, specialist cardiologist, works at the Institute of Cardiology, Jagiellonian University Medical College and at the Department of Electrocardiology, at the John Paul II Hospital in Kraków. His research interests primarily include electrocardiology, cardiovascular implantable electronic devices, mechanisms and biomarkers of cardiovascular diseases (especially cardiac arrhythmias), translational medicine with applications in cardiovascular medicine, cardiac imaging and rare cardiovascular diseases and disorders. He served as reviewer or expert for leading cardiology Journals, including European Heart Journal, Journal of the American College of Cardiology and PLOS Medicine as well as for national and foreign Institutions. He gained valuable clinical and research experience during his visits and trainings at the Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK, at the Cardiovascular Division in the Department of Medicine at Washington University School of Medicine in Saint Louis, Missouri, USA, and at Barnes Jewish Hospital, Saint Louis, Missouri, USA. He has received various awards and distinctions, including 1st place in the best student of the Republic of Poland contest (the Student Nobel Prize 2011), a distinction of honour and medal from the Polish Academy of Sciences, Faculty of Medical Sciences (the Doctor Wacław Mayzl Medical Laurel), and the Ministry of Science and Higher Education scholarship for outstanding achievements (2013/2014) and for prominent young scientists (2020). In 2021 he received the International Society of Electrocardiology Bayés ECG Award for his outstanding achievements in electrocardiology (the International Congress on Electrocardiology – joint meeting of the 21st Congress of the International Society for Holter and Noninvasive Electrocardiology and the 48th Congress of the International Society of Electrocardiology). Moreover, he has obtained scholarships from the Foundation for Polish Science. For some more details please see: Cardiovascular Research (2019) 115, e77–e79.

Russia Investigators

Dr. Elena Zaklyazminskaya, MD, PhD

Professor and Head of Medical Genetics Laboratory

Petrovsky Russian Research Centre of Surgery 2,

Abricosovsky per., 119991 Moscow, Russia

Saudi Arabia Investigators

Dr. Enes Elvin Gul, MD, FESC, FEHRA

Department of Cardiology,

Istanbul Medipol University, Istanbul, Turkey

Switzerland Investigators

Dr. Giulio Conte, MD, PhD

Senior Electrophysiologist - Division of Cardiology, Fondazione

Cardiocentro Ticino, Lugano, Switzerland

Privat Dozent - Università della Svizzera Italiana, Lugano, Switzerland

Clinical Scientist – Centre for Computational Medicine in Cardiology (CCMC),

Università della Svizzera Italiana, Lugano, Switzerland

Thailand Investigators

Dr. Janejira Swasdimanont, MD

Sakolnakorn Hospital,

Sakon Nakhon, Thailand

Dr. Janejira Swasdimanont, MD

Sakolnakorn Hospital,

Sakon Nakhon, Thailand

Turkey Investigators

Dr. Göksel Çinier, MD

Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Center,

Istanbul, Turkey

Dr. Ozcan Ozeke, MD

Consultant Cardiologist

Department of Cardiology, Ankara City Hospital, Ankara, Turkey

Dr. Levent Pay, MD

Cardiologist

Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Surgery Hospital

Turkey

Dr. Kıvanç Yalın, MD, FEHRA

Associate Professor

Department of Cardiology,

Faculty of Medicine

Istanbul University-Cerrahpaşa, Cerrahpaşa

Turkey

United Kingdom Investigators

Dr. Sandeep Hothi, MB, BChir, MA , PhD, MRCP (UK), FACC, FESC

Consultant Cardiologist,

New Cross Hospital,

Wolverhampton, United Kingdom

Dr. Kamalan Jeevaratnam, DAHP, DVM, MMedSc (Mal), PhD (Cambridge), MRCVS (UK)

Head of Department of Pre-clinical Sciences,

Faculty of Health and Medical Sciences,

University of Surrey

Guildford, United Kingdom

Mr. Keith Sai Kit Leung, BSc (Hons.)

Medical Student

Aston University Medical School

Birmingham, United Kingdom

Dr. Ka Hou Christien Li, MBBS

University of Newcastle Medical School

Newcastle, United Kingdom

Dr. Vassilios S Vassiliou, MBBS, MA, PhD, MRCP (UK), FHEA, FRCP (Edin), FSCMR, FESC, FACC

Clinical Senior Lecturer (Associate Professor)

University of East Anglia Medical School

Norwich, United Kingdom

United States Investigators

Dr. Rahul Gupta, MD

Lehigh Valley Health Network

Allentown, United States

Dr. Nainesh Patel, MD

Lehigh Valley Health Network

Allentown, United States

Dr. Gan-Xin Yan, MD, PhD

Professor

Director, Basic Cardiovascular Research Lab, Lankenau Institute for Medical Research

Professor of Medicine, Sidney Kimmel College of Medicine, Thomas Jefferson University, Philadelphia

Professor, Lankenau Institute for Medical Research

Professor of Medicine, Xi’an Jiaotong University, China

Dr. Sri Sundaram, MD

Attending Cardiac Electrophysiologist

South Denver Heart Center

Colorado, United States

Vietnam Investigators

Dr. Phong Dinh Phan, MD

Consultant Cardiologist

Bach Mai Hospital, Hanoi

Vietnam