Neurofibromatosis Type 1 is a disorder that causes tumors to grow uncontrollably on nerve tissues. Curcumin is a polyphenol, a chemical that contains multiples of phenol structural units. Polyphenols in curcumin have antioxidant effects and have been proven to disrupt the growth of cancer tumors and inhibit the growth of new tumors, as well as help with neurodegenerative diseases. Studies demonstrate the beneficial effect of curcumin on neurofibromatosis type 1. Extra virgin olive oil is another common food that is high in polyphenols, so this experiment tests to see if extra virgin olive oil will have beneficial effects on neurofibromatosis type 1, using curcumin as a baseline effect. Working extra virgin olive oil into daily meals, allows more polyphenols into the system, which could help patients suffering from neurofibromatosis type 1. Curcumin or olive oil was introduced into the media of wild and transgenic mutant flies, which groom significantly more. The number of times the flies groomed within three minutes determined if the polyphenols had a beneficial effect on the neurofibromatosis type 1 condition of the mutant flies. Curcumin and olive oil were found to have significant results in lowering the amount of times the mutant flies groom themselves, on average the mutant flies groomed 18.5 times in three minutes, this got lowered to 8.1 and 8.1 times after the introduction of curcumin and olive oil. This means that if a neurofibromatosis type 1 patient consumes more curcumin or olive oil, the polyphenols may improve the condition.