Passiflora incarnata, also known as passionflower, has been growing more popular in the homeopathic market, however due to few clinical trials and research, its efficacy or negative side effects are not known. The FDA withdrew passionflower approval in 1978 when manufacturers could not provide evidence of effectiveness or safety. Some of the acclaimed remedies passionflower provides includes treatment for anxiety, insomnia, and can be used as an antioxidant, however some of the reported side effects are dizziness, drowsiness, and abnormal heart rate. The purpose of this project is to give drosophila larva various concentrations of passionflower, calculated based off of human dosages, to see how it affects their heart rate. Larva were administered 0.00371% passionflower, equivalent to 1.5mL for humans per day, 0.0111% passionflower, equivalent to 3.0mL for humans per day, and 3.71%, which is ImL for larva. The concentrations were put in an apple juice agar along with 30 larva, which were then kept in a drosophila incubator for 72 hours as they are exposed to the passionflower, Control agar with larva were conducted as well to establish a baseline heart rate. After 3 days, the larva were removed from the petri dishes, and around 10 larva were left for each trial because some of them turned into pupa during the trial. Heart rates were measured under a microscope; the cardiac tube was recorded beating using a phone for 15 seconds then multiplied by four to get beats per minute. The average heart rate was 254 beats per minute, the 0.00371% passionflower concentration heart rate was 313 beats per minute, the 0.0111% passionflower concentration heart rate was 3236 beats per minute, and the 3.71% passionflowe concentration heart rate was 358 beats per minute. Through ANOVA testing, the p values of the concentrations when comparing it to the control were all under 0.005, making it statistically significant. In addition, the Scheffe and Bonferroni and Holm test results show that there is a significant difference for each trial as the concentration increases since the p value is under 0.005, which means as the passionflower dosage increases so does the heart rate. Overall, the passionflower did cause the heart rate of larva to increase, and as the concentration increased, it caused a faster heart rate. Future studies recommended in correspondence to this study includes what chemical component of passionflower causes an increase of heart rate, as well as comparing the heart rates from passionflower to heart rates from other homeopathic remedies.