With the misuse of antibiotics, it's possible that over the course of our generation other methods for reducing bacterial count or killing bacteria will possibly become essential to mankind's survival. Almost all bacteria have sensory systems that use to recognize the external environment and react to that stimulus. This process is called chemotaxis and bacteria chemotaxis is defined as the movement of bacteria towards a desired location die to chemical stimulus. In general most bacteria are stimulated to move towards areas that contain the greatest concentration of their most desired nutrients. My project attempted to solve this problem. Methods/ Materials

To model a patient's circulatory system I created a medical device using a peristaltic pump, plastic tubing and a plastic sphere. The peristaltic pump modeled the patient's heartbeat; the tubing represented the external system that would ideally circulate the blood fluid that contained the bacteria of the patient, and the plastic sphere (which I called the "Secular Zone") that held the bacteria's amiable chemicals. In my project I used Escherichia coli and its preferred

chemoattractant, galactose-stored inside the plastic sphere- as the basis for my research. I used changes of turbidity (measured with a spectrophotometer) inside the "Secular Zone" as an indication of bacterial movement. Results: My paired T-test compared two sets of experimental data, the control where the "Secular Zone" contained no galactose and one where the "Secular Zone" contained concentrated galactose. The results failed to reject my null hypothesis, meaning that movement of the bacteria was insignificant. Conclusions: While the data suggests the opposite, I still believe that this idea is possible. Problems could have occurred in the flow rate of the "blood" fluid running through the "Secular Zone". Future studies that need to be done are as following: One, how long does it take for bacteria to move across a given distance? This would indicated how long to run the apparatus and also determine the flow rate of the apparatus. Two, does this method work with bacteria that exhibit no chemotactic behavior? Finally, does increasing the concentration of the chemoattractant increase bacteria's movement/ attraction to the Secular Zone? Summary In this experiment I tested whether a bacteria's attraction to chemicals be manipulated to reduce bacterial count inside the body?