Tell your doctor right away if you have any serious side effects, including: easily broken bones, pain/swelling of the joint/muscle/tendon, mental/mood changes (such as depression), numb/tingling skin, swelling hands/ankle/feet, shortness of breath, unusual vaginal discharge/bleeding/burning/itching/odor, pain/redness/swelling of arms or legs, vision changes, signs of liver disease (such as nausea/vomiting that doesn't stop, stomach/abdominal pain, yellowing eyes/skin, dark urine).

Because estrogen is known to have a positive effect on mood, it is reasonable to assume that these hormonal therapies that suppress estrogen activity might have the opposite effect. A recent article reviews the side effects commonly reported in women treated with these hormonal treatments, including hot flashes and mood changes. This article discusses a case of a 56-year-old woman with no prior psychiatric history who develops severe mood changes after treatment with anastrozole. The symptoms of depression resolve after discontinuation of treatment.

Arimidex Depression News

DOWNLOAD 🔥 https://bltlly.com/2y1JRf 🔥

Exactly how frequently depression occurs in women treated with these hormonal therapies has not been well-studied. Clinically depression is observed in some breast cancer patients receiving hormonal therapies. Large clinical trials have yielded generally positive results regarding the risk of depression in women treated with tamoxifen. In the Study of Tamoxifen and Raloxifene (STAR), women at high risk for breast cancer received tamoxifen (n = 973) or raloxifene (n = 1010). Depressive symptoms initially increased after the start of therapy, followed by a partial return to baseline levels. The change was small (e.g., about 1.5 points in CES-D scores).

The data suggest that mood changes are not commonly associated with hormonal therapies for breast cancer. This is reassuring; however, we do know that depression is relatively common in women diagnosed with breast cancer. Whether the depression stems from the effects of hormonal modulation or other factors, for instance, the burden of having a life-threatening illness, we must recognize that this population of women is at high risk for psychological distress and depression and should be routinely assessed.

While some articles have advocated the avoidance of all SSRI antidepressants, depression is common among women being treated for breast cancer and may be more common in those receiving tamoxifen. Depression should not be ignored in this situation; a conservative approach to its management would emphasize the careful section of co-administered to avoid significant interactions.

The possibility that SSRIs might, by inhibiting CYP2D6, slow the metabolism of tamoxifen and reduce its effectiveness is a concern given that as many as one-fourth of breast cancer patients experience clinical depression and may be treated with SSRIs. In addition, SSRIs are sometimes used to treat hot flashes caused by hormone therapy.

Michelle says:

 Hey gang! I'm so glad i found this! I had double mastectomies and chemo for a DCIS that escaped the duct (dense breasts didn't show cancer at my annual for YEARS). Anyway, my oncotype was 29 so they put me on Arimidex. NO. Joint pain, muscle spasms, severe depression (I've never been depressed, I go more towards worried anxious crazy lady), and mental/dementia-like fog. I stopped and refused to get on anything else for 6 months. My gut tells me to treat it naturally b/c that's who I am. Then doc convinced me to try Tamoxifen. It sat on my counter for weeks then I tried it. 2 days in, I had horrible headaches and insomnia. Btw I'm already in menopause b/c of chemo at 45 so the hot flashes were already there. Anywhoo, after doing my research, I read that 5mg works the same as 20 for DCIS patients. I know mine was invasive but who care it's either 5mg or nothing. So far, the 5mg is much better. Still some sleep stuff and frequent urination, but SO much better. How is there not a better way to prevent by now? This stuff is so toxic!! Love to all of you and man what a journey.

Amanda Krrstedt says:

 Hi everyone.Im so happy that Im mot alone in this and also sad to read that so many suffer. I was diagnosen with Her2 positive breastcancer nov 2019 and was surgery first, then taking out eggs(IVF) and then started chemo and then radiation in 2020. Ive been on tamoxifen meditation (once a day) and Zoladex injections (once a month) since Jan 2020 and july 2020.Its been really horrible with hot flashes, sleepless nights, anger, irritation, sadness, anxiety, depression, panic attacks, weight gain, hard to concentrate etc. And I also feel that after i was treated I was working and studing and was stressig alot. And now it Feels like It just hut my again, The tiredness, The fatigue, brainfog. But it Feels like people around me think im crazy and dont understand.My energy is so low.Ive been thinking if I will be able to make it 5-10 years with these medications. I was thinking of aiming towqrds 5 years. But The weight gain is making me frustrated. But im trying to love and accept this version of me roght now, trying to find a Spiritual path in all of this, doing alot of meditation and yoga to still my mind and it is helping.If there is anyone that wants to talk more about this I would be happy to do that, to be able to help eachother.Please send to my email:[email protected]Big hug to you all.

Andrea says:

 I have just the same problem! 6 months of Nolvadex and I'm thinking about to quit. You can e mail me? My bones hurts me, two weeks of depression, nights sweats, brain fog and leukopenia.

Ann Marie Saccente says:

 Recent diagnosis of state 2 invasive lobular, lumpectomy in Aug 2023, 6 days of radiation and now they want me to take arimidex. I have severe arthritis, right, shoulder, hip and knee total replacements in 10 years. Need the other shoulder replacement next year. Im totally against estrogen completely being depleted from my body. I'm already suffering my joint pain, had horribel flashes during menopause. Im 72 yrs of age. I'm so anxious about this pill, i've had it for a month and can't even look at the bottle. Reading your stories, mine cancer and treatment is nothing.... And I know the quality of my life will change the day I swallow this pill. Not feeling positive .... Ann Marie.

LNV says:

 Hi, 34 years old. Last year, at 33, I found a small lump in my right breast. I had stage 1, grade 3, invasive carcinoma, N-0; I found it very early, it was small 1.7. I did a nipple sparing unilateral mastectomy, with direct implant. No radiation was required, and chemo was optional because my score was in the middle; chemo only was 1.2% beneficial for me, because of young age, so FOR ME, the side effects of chemo would have been worst than my cancer treatment per se. Anyways, I started tamoxifen prior my surgery last year, and have been in tamoxifen over a year. Because I'm in my fertility years, the docs told me I had to stay without trying to have babies, and with my tamoxifen at least the first two years (until 03/2024), then I have to clean my system , have a baby, and continue my remaining 5 year treatment with tamoxifen. I don't know which side effects are normal and due to tamoxifen, and which symptoms are related to the psychological effects of having/surviving breast cancer. Our bodies definitely change, so is human that we feel some how depress. But godddddddddd, I'm definitely more emotional with this pill. And the mood swings are a real thing. Obviously the night sweats are too, but for me, their not the worst side effects. The emotional rollercoaster, the fatigue and the depression is. Also, thinning of hair and loss of lashes. Thank god my libido is intact though. I told my oncologist those symptoms, the response was so unsatisfying... " therapy will help, and doing at least 4 days of exercise to alleviate the side effects of the pill". No shit, I told him...hahah . I do exercise, but I have fatigue so its not helping, and obviously the therapy will heal the emotional factors, but then again, I don't want to still talk about the C word. No everyone understands what we have gone through, and every cancer is different. So I don't want a stranger telling me how I'm supposed to feel about something that maybe she/he doesn't have idea. Anyways... just wishing that I can deal with the side effect for one more year. And stop, and be able to have a baby. Anyone here that have stop the tamoxifen to have babies?

Valerie Elliott says:

 I went through menopause many years ago. My only problem wax hot flashes - no other symptoms. I started Tamoxifen a little over two months ago and do not like the way I feel. Extreme hot flashes, body aches, depression, nausea and headaches. I will try to continue on the Tamoxifen but dont think I will do it much longer if all of these side effects persist. Menopause was never like this!

HEATHER MIXON says:

 Small lump found in mammogram. Never knew it was there. Size of a staple, also found a microscopic place in one lymph node. I've had both removed and 6 weeks of radiation. It's been a year now. I've been struggling with so many side effects with the tamoxifen. I'm 49 as of March 5th. The discomfort in my vaginal area I can't take. I've been a good sport about the hot flashes and night sweat, depression, lack sleep but this vaginal stuff is a whole new level. I've reached out to different doctors on my team and I honestly get no relief. I feel like I'm just not sick enough for anyone to really hear me. As of today I've not been on the tamoxifen 8 days.and I feel much better. This week will be my 5th time to stop. This time I stopped it on my own do to the vaginal discomfort. I just feel like I'm young to take it and feel so bad and I'm to take my chances. I do have a since of peace about it. Sending the power of understanding to your family members and doctors along with mine. God Bless

Jennifer says:

 Alex,I was also diagnosed with DCIS in 2019. I am also BRAC negative. When it was found, I went for two consultations for opinions as this was new to me. I'll never forget that my doctor said it was the "best worst news" I'd ever get. I was given the same choices. But they were just that, choices. Both breast surgeons gave me the option of elective surgery with reconstruction or a lumpectomy followed by radiation and Tamoxifen. I opted for the lumpectomy also because I was not ready for such a drastic surgery such as a mastectomy. I had my lumpectomy and my sentinel lymph node removed. I did 25 rounds of radiation and I have now been on tamoxifen for 3 years. (2 more to go) I looked at it this way...Anything that will reduce my risk of reoccurrence was something I was/am willing to do. I began with 20 mg of tamoxifen, then went to 10mg. I'm now on 5 mg. I will admit that the radiation will leave you exhausted and burnt to a crisp, but you can do it. I napped every single day because I had to. The biggest issues I have with tamoxifen are the mood swings and the fatigue. I had hot flashes and night sweats in the beginning years, but they have gotten better. We are all different so we will all tolerate the meds differently. What I think of as no big deal may be a "hell no" for you. My point: give it all a shot. You can always say it's not for you but just try. Any prevention that we can give ourselves is another day we sleep easier. (unless you have night sweats!) : ) I just wanted to know for myself that I did all I could for myself. Something is better than nothing, I say. The rest is up to the fates. Good luck with everything! be457b7860

Eventide Anthology X Crack Straightinstmankl

biwi ki adla badli(sex stories in urdu font) hit

pes 2013 soundtrack playlist 19

Toonpur Ka Superrhero Movie Download 720p Hd defflag

Hello Microsoft Band. Goodbye Fitbit and Pebble.