Welcome to my web page. I am Dr. Apurba Paul, a Postdoctoral Research Associate at the Department of Electrical Engineering, University of Notre Dame, working with Prof. Gregory Timp.
I have done my Ph.D. from the Indian Institute of Science, Bangalore under the supervision of Prof Vasant Natarajan. My Ph.D. research was to study the malaria-infected red blood cells using optical tweezers.
Light gradient forces, produced by a time-multiplexed optical standing wave, are used to assemble voxels consisting of nanoparticles into 3D structures on a hydrogel scaffold. Hundreds of nanoparticles can be manipulated into a complex heterogeneous voxel this way, and then the process can be repeated by stitching together voxels to form a metamaterial of any size, shape, and constituency
When a single denatured protein passes through a sub-nanometer diameter nanopore, added by an electric field, it changes the electrolytic current through the pore. Each nucleotide produces its characteristic current through the pore which can be read back using high bandwidth amplifier. Nanopore sequencing has the potential for very long reads, reducing the computational burden posed by alignment.