Dr. Ambuja Navalkar, Ph.D.
Dr. Ambuja Navalkar, Ph.D.
DST-INSPIRE FACULTY (Principal Investigator)
National Centre for Cell Science, Pune, India.
Biochemistry, Biophysics and Oncology
About
My expertise lies in the domains of biochemistry, biophysics, and cancer biology. We are interested in understanding how biomolecular interactions can alter functional behavior in healthy versus diseased conditions. We explore the structure-function-regulation relationship in higher-order assemblies, such as aggregates and condensates. This research advances fundamental biology by uncovering how dynamic biomolecular assemblies regulate cellular function, with direct relevance to disease mechanisms such as cancer and neurodegeneration, while guiding rigorous validation and future discovery.
Research Experience
DST-INSPIRE Faculty
National Centre for Cell Science, Pune, India (2024-Ongoing)
Research: Nuclear biomolecular condensates in oncology
Postdoctoral Research Associate
Supervisor: Prof. Tanja Mittag
Structural Biology, St. Jude Children's Research Hospital, USA (2021-2024)
Research: Myc phase separation in transcriptional condensates
Institute Postdoctoral Fellow
Department of Bioscience and Bioengineering,
Indian Institute of Technology Bombay (IIT Bombay), India (2020- 2021)
Research: Phase separation and amyloid formation of p53
Ph.D. (Biophysics and Cell Biology)
Supervisor: Prof. Samir Maji
Department of Bioscience and Bioengineering,
Indian Institute of Technology Bombay (IIT Bombay), India (2015-2020)
Thesis: p53 amyloid formation: Implications in cancer pathogenesis
Background
Master of Science, Biotechnology
Maharaja Sayajirao University of Baroda, Vadodara, India.
Bachelor of Science, Biotechnology
Ruia College, Department of Biotechnology, University of Mumbai, Mumbai, India.
News
Appointed Guest Editor for Springer Nature Discover Life (2025)
Special Issue: Biomolecular Condensates in Physiology and Disease (Special Issue Link)
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