The 6th Symposium on Biophysics Postgraduate Research in Hong Kong
第六屆香港生物物理研究生學術年會
Jan 6th 2024, Hong Kong Baptist University
Introduction
The 6th Symposium on Biophysics Postgraduate Research in Hong Kong aims to provide a platform of interactions for researchers in the area of biophysics from all UGC funded universities. By bringing together researchers from different institutions, this symposium aim to facilitate the sharing of cutting-edge research and ideas, and foster new collaborations that will drive the field forward. This series of symposiums has been held successfully five times at different universities, including CUHK (2014), HKBU (2016), CityU (2017), HKUST (2018), and CUHK(2019), but was unfortunately interrupted due to the pandemic. The organizing committee decided to resume the symposium to promote biophysics postgraduate research in Hong Kong.
This 6th symposium will be held at Hong Kong Baptist University on Jan 6th 2024. The Chief Scientist Yuji Sugita from RIKEN Japan will deliver the keynote talk. The symposium also includes invited talks, oral presentations and a poster session. No registration fee is required, but all the participants of interest are required to register in advance. The deadline for registration is Dec 15th 2023. Students are highly encouraged to give oral or poster presentations.
This symposium has been supported by Research Grants Council Postgraduate Students Conference/Seminar Grants.
Keynote speaker
Yuji Sugita
RIKEN Cluster for Pioneering Research, Japan
RIKEN Center for Biosystems Dynamics Research, Japan
RIKEN Center for Computational Science, Japan
Talk Title: Protein functions in crowded cellular environments
Abstract: Inside of the cell is highly crowded with proteins, RNAs, their complexes, and various metabolites. How proteins can maintain conformational stability and properly function in crowded cellular environments is a fundamental question in molecular and cellular biology. To answer the question using computer simulations, Extensive molecular dynamics (MD) simulations with multi-scale molecular models that include atomistic, coarse-grained (CG), and hybrid QM/MM models are useful. For this purpose, our group has developed multi-scale MD software, GENESIS, and optimized it to supercomputers like Fugaku.
After introducing our computational methods and software developments, I will introduce several application studies related to crowded cellular environments. In each simulation, we utilized the most suitable molecular models (either atomistic, CG, or QM/MM) and carried out extensive simulations using supercomputers like K computer, Fugaku, or Anton2. These simulations highlight the importance of conformational flexibilities of proteins and non-specific molecular interactions in biological functions in cellular environments.
Invited speakers
Zhi Qi
Peking University
Talk title: Deciphering the molecular mechanism of DNA-protein interactive co-condensation
Wei Han
Hong Kong Baptist University
Talk title: Bridging Atomic Details and Overall Kinetics: A Multiscale Computational Approach to Understand Peptide Self-Assembly
Yu Li
The Chinese University of Hong Kong
Talk title: RNA structure prediction with deep learning
Haibin Su
The Hong Kong University of Science and Technology
Talk title: Dynamic Expedition of Leading Mutations in SARS-CoV-2 Spike Glycoproteins
Qianyuan Tang
Hong Kong Baptist University
Talk title: Unravelling Protein Dynamics through Analysis of AlphaFold Prediction Error
Lizhe Zhu
The Chinese University of Hong Kong, Shenzhen
Talk title: Fine-tuning activation specificity of G-protein-coupled receptors via automated path searching
Xiangze Zeng
Hong Kong Baptist University
Talk title: From the Single-Chain Behavior to Phase Behavior of Intrinsically Disordered Proteins
Schedule
Date: Jan 6th 2024
This is a one-day symposium including talks and poster presentations. Please see the detailed program below.
Program_book_V6.0.pdfVenue
Venue:
Room 905, Sir Run Run Shaw Building, Ho Sin Hang Campus
Hong Kong Baptist University, 224 Waterloo Road, Kowloon Tong, Hong Kong
Please see the following direction to the conference room.
Registration
Please submit the following google form for registration. The symposium accept poster presentations and contributed talks. Please note that most talks are by invitation. A small number of selected talks from registered participants will be included in the meeting program subject to the availability of time slots.
Organizing committee
Prof. Yi Wang, The Chinese University of Hong Kong
Prof. Jun Fan, City University of Hong Kong
Prof. Ying Lung Steve Tse, The Chinese University of Hong Kong
Prof. Haibin Su, The Hong Kong University of Science and Technology
Dr. Xiangze Zeng, Hong Kong Baptist University
Student helpers
Fangke Chen
Wenwen Leng
Yuxiang Zheng
Zecheng Zhang
Contact us
If you have any enquiries regarding this symposium, please feel free to contact Dr. Xiangze Zeng (Email: xiangzezeng AT hkbu.edu.hk).