Advanced Quantum Optical Imaging and Sensing Surpassing Classical Limits
Advancements in quantum optics enable imaging and sensing protocols that surpass classical constraints. This work presents three major achievements in quantum-enhanced metrology, demonstrating how spatial and temporal photon correlations achieve unprecedented performance in biological imaging and remote sensing.
First, we introduce a quantum phase imaging technique exploiting sub-shot-noise spatial correlations from Spontaneous Parametric Down-Conversion (SPDC). By integrating these correlations with non-interferometric methods, we overcame the trade-off between noise reduction and spatial resolution. This enabled the first demonstration of a quantum advantage in wide-field imaging of biological cells, providing high-contrast phase information below the shot-noise limit [1].
In super-resolution microscopy, we developed a non-invasive fluorescence microscopy technique based on pixel-level photon statistics [2]. Our method enhances classical frameworks like Super-resolution Optical Fluctuation Imaging (SOFI) and is fully compatible with Structured Illumination Microscopy (SIM). This synergy boosts resolution further, pushing sub-diffraction boundaries without increasing phototoxicity [2].
Finally, we address quantum advantages in Time-of-Flight (ToF) ranging. Using a multiple-hypothesis testing model, we verified superior precision in quantum-enhanced distance measurements [3]. Crucially, we explore covert sensing, showing that detecting a target while remaining undetected is uniquely possible through low-photon-number quantum correlations. This provides a novel justification for quantum LIDAR and secure, non-invasive detection [4].
These results represent a significant step toward integrating quantum states into next-generation optical instruments.
[1] A. Paniate, G. Ortolano, S. Soman, et al. Optica 13, 375-385 (2026)
[2] F. Picariello, E. Losero, S. Ditalia Tchernij, et al. Optica 12, 490-497 (2025).
[3] G. Ortolano, I. Ruo-Berchera, Phys. Rev. Research 7, L022059 (2025).
[4] G. Ortolano, I. Ruo-Berchera, L. Banchi, Phys. Rev. Lett. 136, 060801 (2026)