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"Nothing in life is to be feared; it is only to be understood. Now is the time to understand more, so that we may fear less" - Marie Curie
Welcome to my corner of the web!
Welcome to my corner of the web!
I'm Raphael Onuku, a passionate Medicinal Chemist and PhD researcher at the University of Michigan, Ann Arbor. My academic and scientific journey has taken me from the University of Nigeria to Taipei Medical University in Taiwan, where I was honored with the MOE Taiwan Government Scholarship, and now to the forefront of multidisciplinary research in drug discovery.
I'm Raphael Onuku, a passionate Medicinal Chemist and PhD researcher at the University of Michigan, Ann Arbor. My academic and scientific journey has taken me from the University of Nigeria to Taipei Medical University in Taiwan, where I was honored with the MOE Taiwan Government Scholarship, and now to the forefront of multidisciplinary research in drug discovery.
Driven by a deep curiosity about the molecular basis of disease, my work lies at the intersection of computational chemistry, peptide science, cancer, and infectious disease research. I am particularly focused on the design and development of next-generation anti-infective agents, integrating in silico strategies with experimental synthesis to accelerate discovery.
Driven by a deep curiosity about the molecular basis of disease, my work lies at the intersection of computational chemistry, peptide science, cancer, and infectious disease research. I am particularly focused on the design and development of next-generation anti-infective agents, integrating in silico strategies with experimental synthesis to accelerate discovery.
My expertise spans:
My expertise spans:
De novo ligand design: Crafting potential inhibitors for target enzymes.
De novo ligand design: Crafting potential inhibitors for target enzymes.
Structure-based molecular docking and virtual screening: Exploring large chemical libraries to identify high-potential ligands.
Structure-based molecular docking and virtual screening: Exploring large chemical libraries to identify high-potential ligands.
Molecular dynamics simulations: Capturing the nuanced behavior of biomolecular systems in silico.
Molecular dynamics simulations: Capturing the nuanced behavior of biomolecular systems in silico.
Solid-phase peptide synthesis (SPPS): Synthesizing and optimizing macrocyclic and linear peptides for biological evaluation.
Solid-phase peptide synthesis (SPPS): Synthesizing and optimizing macrocyclic and linear peptides for biological evaluation.
Peptidomimetic design and stability profiling: Enhancing the therapeutic potential of peptides through structural innovation.
Peptidomimetic design and stability profiling: Enhancing the therapeutic potential of peptides through structural innovation.
My mission is clear: to design and decipher the intricacies of small active molecules that can evolve into groundbreaking drugs. By leveraging cutting-edge computational tools and hands-on synthesis, I aim to address the pressing challenges of cancer, antimicrobial resistance, and neglected tropical diseases.
My mission is clear: to design and decipher the intricacies of small active molecules that can evolve into groundbreaking drugs. By leveraging cutting-edge computational tools and hands-on synthesis, I aim to address the pressing challenges of cancer, antimicrobial resistance, and neglected tropical diseases.
As I continue advancing in both research and translational impact, I’m always open to collaboration with visionary scientists, industry innovators, and global health partners. If you are interested in computational drug design, peptide-based therapeutics, or multidisciplinary strategies in anti-infective discovery, I welcome you to connect.
As I continue advancing in both research and translational impact, I’m always open to collaboration with visionary scientists, industry innovators, and global health partners. If you are interested in computational drug design, peptide-based therapeutics, or multidisciplinary strategies in anti-infective discovery, I welcome you to connect.
Let’s shape the future of medicine—together!
Let’s shape the future of medicine—together!
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