Overview of our Integrated Systems Biology Approach
We are working towards molecular-based disease stratification.
Our general approach involves correlating clinical, molecular, and histopathologic phenotyping, along with validation in model systems.
December 08, 2016
Investigation of Kidney Biomarkers To Track Lupus Progression and Signs of Complications
We recently collaborated with Emily Somers, Ph.D., Sc.M., an associate professor of internal medicine (rheumatology), environmental health sciences and obstetrics and gynecology at U-M and a member of the U-M Institute for Healthcare Policy and Innovation, to help identify biomarkers that could lead to early detection of kidney involvement in lupus patients. We presented our findings at the American Society of Nephrology’s Kidney Week 2016 meeting, showing that levels of epidermal growth factor in the urine of lupus patients provided an improved ability to distinguish those with kidney involvement from those without.