Reinventing drug discovery through chemical biology

Tentative Schedule

9:00 - 10:00 Registration

10:00 - 10:10 Welcome

10:10 - 11:00 Dusty Maly, Ph.D., Professor of Chemistry, University of Washington

Modulating Phosphotransferase-Independent Kinase Functions from a Distance

11:00 - 11:30 Matthew Soellner, Ph.D., Research Assistant Professor of Internal Medicine, University of Michigan

Selective Proteolysis to Study the Global Conformation and Regulatory Mechanisms of c-Src Kinase

11:30 - 12:00 Amanda Garner, Ph.D., Assistant Professor of Medicinal Chemistry, University of Michigan

Identification of Kinase-Targeted Drug Combinations using Chemoproteomics

12:00 - 1:30 Lunch and Poster Session; Chemistry Atrium

1:30 - 1:45 Alexander Vizurraga, Ph.D. Candidate, Department of Pharmacology, University of Michigan

Discovery of First-in-Class Small Molecule Adhesion GPCR Modulators

1:45 - 2:00 Jonah Vilsek, Ph.D., Post Doctoral Fellow of Chemistry, University of Michigan

Accelerating Drug Discovery Through 'in silico' Lead Optimization with Multisite λ-Dynamics

2:00 - 2:30 Nouri Neamati, Ph.D., John G. Searle Professor of Medicinal Chemistry, University of Michigan

Targeting Protein Disulfide Isomerase in Cancer

2:30 - 3:00 Jolanta Grembecka, Ph.D., Associate Professor of Pathology, University of Michigan

Development of New Targeted Therapies for Leukemia

3:00 - 3:50 Daniel Nomura, Ph.D., Associate Professor of Chemistry, Molecular & Cell Biology, and Nutritional

Sciences & Toxicology, University of California - Berkeley

Reimagining Druggability using Chemoproteomic Platforms

Pre-registration by May 12th is required to receive the catered lunch.