2023 Midwest Computational Biology Workshop at TTIC

Tuesday, September 12, 2023

Toyota Technological Institute at Chicago

5th floor - Main Lecture Room

6045 S. Kenwood Ave, Chicago, IL 60637

The 2023 Midwest Computational Biology Workshop is scheduled for September 12, 2023, at the Toyota Technological Institute at Chicago and will focus on recent advancements in modeling the immune system. The goal of the workshop is to establish a collaborative forum for researchers specializing in the integration of computational and immunological research disciplines. The morning sessions will center on the analysis of B-cell repertoires, emphasizing the role of recent computational algorithms in enhancing our understanding of antibody functions and responses. In the afternoon, the discussion will pivot to the interplay between machine-learning techniques and high-throughput technologies. Our goal is to cultivate a holistic perspective, encouraging the synthesis of computational techniques with immunological research to foster a deeper understanding of the immune system through quantitative and computational lenses. This workshop has been graciously supported by the 2023 TTI-Chicago Summer Workshop Program. 

Registration

Registration is free but limited by seating capacity. Please register using this form.

Navigating the UChicago campus

TTIC is located on the south-east corner of the University of Chicago campus. The best way to get to here from Knapp or other biomedical buildings is to walk south to 60th St, and then walk east until you reach Kenwood Ave.  TTIC is on the corner of Kenwood and 61st. (Other routes via Google map).

Parking

There is free parking in two commuter parking lots, about 7-10 min walk away, at 60th St and Stony Island Ave and 63rd St and S Kenwood Ave. 

There is also free, but limited, street parking on many streets near TTIC (just beware of "permit parking" and "street cleaning" signs!). For example, parking can be found on 61st Street (between Woodlawn Ave and Blackstone Ave) and on Dorchester Street (between 60th and 61st Streets).

Workshop Schedule

Tuesday, September 12

8:30-8:55: Continental breakfast at TTIC

8:55-12:15: Computational Insights into B-Cell and Antibody Repertoires

8:55-9:00: Introductory Remarks, Aly Khan, University of Chicago

9:00-9:45: Kenneth Hoehn, Dartmouth. Phylogenetic analysis of B cell migration, differentiation, and evolution over time

9:45-10:30: Leah Weber, El-Kebir Lab, University of Illinois Urbana-Champaign. Tree Inference of B cell Clonal Lineages

10:30-10:45: Snacks and Coffee Break

10:45-11:30: Marcos Vieira, Cobey Lab, University of Chicago. Germline-encoded specificities and the predictability of the B cell response

11:30-12:15: Patrick Koenig, 23andMe. Enriching antibody sequence data with structural information

12:15-1:25: Lunch at TTIC

1:25-5:00: Computation and Experiment: Modeling the Immune System

1:25-1:30: Introductory Remarks, Derek Reiman, Toyota Technological Insitute at Chicago

1:30-2:15: Yuri Pritykin, Princeton University. Regulatory genomics of T cells in cancer and infection

2:15-3:00: Hatice Osmanbeyoglu, University of Pittsburgh. Computational methods for delineating cell context-specific regulatory programs

3:00-3:45: Savas Tay, University of Chicago. Proximity sequencing for simultaneous measurement of proteins, protein complexes and mRNA in single cells

3:45-4:00: Snacks and Coffee Break

4:00-4:45: Jie Zhou, University of Chicago. Identify and Target Proteolytic Neoepitope in Cancer

4:45-5:00: Wrap up at TTIC 

Organizers:

Previous meeting:

2019 Midwest Comp Bio Workshop: https://sites.google.com/ttic.edu/compbioworkshop2019