This mural is a play on the words 'Don't Drink and Drive' since derive and drive sound similar. Taking a derivative is called differentiating. You should not take the derivative of a drink with respect to t. If you do, you will make all kinds of errors, such as E=mc^3 instead of ^2, V=I-R instead of I*R, n1sin(theta2)=n2cos(theta1) instead of n1sin(theta1)=n2sin(theta2), E=K-U instead of K+U, K=1/3mv^3 instead of 1/2mv^2, or F=sqrt(ma) instead of just ma. These errors will cause major problems in your attempts to solve physics questions!